polr3a
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  • Official Full Name
  • polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
  • Background
  • The protein encoded by this gene is the catalytic component of RNA polymerase III, which synthesizes small RNAs. The encoded protein also acts as a sensor to detect foreign DNA and trigger an innate immune response.
  • Synonyms
  • POLR3A; polymerase (RNA) III (DNA directed) polypeptide A, 155kDa; DNA-directed RNA polymerase III subunit RPC1; hRPC155; RPC1; RPC155; RNA polymerase III subunit C1; RNA polymerase III subunit C160; RNA polymerase III 155 kDa subunit; RNA polymerase III
Cat.#:POLR3A-1639CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken POLR3A
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Cat.#:POLR3A-8286ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish POLR3A
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Involved Pathway

POLR3A involved in several pathways and played different roles in them. We selected most pathways POLR3A participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR3A were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
ITPA; PDE9A; POLR3G; NT5C; POLD1; AK4; PDE1B; PKLR; ADSSL; PAPSS2B
Pyrimidine metabolism
ENTPD1; UPP1; POLE; POLA1; POLR2H; DPYDB; POLR3GL; POLR1B; CMPK; NT5M
Metabolic pathways
POLR3C; GALNT6; ALAS1; ackA; B3GNT2B; POLR2GL; CYP19A1; PIGH; COMTA; MT-ND1
RNA polymerase
POLR1C; POLR2GL; POLR2H; POLR2B; POLR2D; TWISTNB; POLR3D; POLR3B; POLR2C; POLR2L
Cytosolic DNA-sensing pathway
IFN-a; TBK1; TMEM173; POLR2H; IFNB1; IFNA1; IFNA4; POLR2F; Ifna11; OSTN

Protein Function

POLR3A has several biochemical functions, for example, DNA binding, DNA-directed RNA polymerase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR3A itself. We selected most functions POLR3A had, and list some proteins which have the same functions with POLR3A. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein POU5F3; UHRF2; NUCB1; TFB1M; EBF4; NFE2L2A; TRAF4; FANCI; TRIM30A; CDC5L
Function DNA-directed RNA polymerase activity
Related Protein PRIM2; POLR3G; RPAP1; POLR1C; POLR2M; POLR2I; POLR2B; MED20; POLR3A; MED21
Function metal ion binding
Related Protein AOC1; ARFGAP3; ZFP513; GART; ZNF488; RARGB; ITGB7; ZNF207A; TERT; NSF