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POM121

Official Full Name

POM121 membrane glycoprotein
Overview

The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the FG-repeat-containing nucleoporins. The protein encoded by this gene is an integral membrane protein that localizes to the central spoke ring complex and participates in anchoring the nuclear pore complex to the nuclear envelope. Alternatively spliced variants that encode different protein isoforms have been described but the full-length nature of only one has been determined.
Synonyms

POM121; POM121 membrane glycoprotein; POM121 membrane glycoprotein (rat); nuclear envelope pore membrane protein POM 121; DKFZP586G1822; DKFZP586P2220; KIAA0618; POM121A; MGC3792; Nuclear envelope pore membrane protein POM 121A; Nuclear pore membrane protein 121 kDa; Nucleoporin Nup121; NUP121; P145; Pore membrane protein of 121 kDa; OTTHUMP00000160223; OTTHUMP00000160224; OTTHUMP00000211425;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Rat	POM121-4574R	Recombinant Rat POM121 Protein	Mammalian Cell	His	Inquiry
Rat	POM121-4234R	Recombinant Rat POM121 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	POM121-4234R-B	Recombinant Rat POM121 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

POM121 Related Articles

POM121 involved in several pathways and played different roles in them. We selected most pathways POM121 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with POM121 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

POM121 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by POM121 itself. We selected most functions POM121 had, and list some proteins which have the same functions with POM121. You can find most of the proteins on our site.

Function	Related Protein

POM121 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POM121 here. Most of them are supplied by our site. Hope this information will be useful for your research of POM121.

Harel, A; Orjalo, AV; et al. Removal of a single pore subcomplex results in vertebrate nuclei devoid of nuclear pores. MOLECULAR CELL 11:853-864(2003).

Coy, JF; Wiemann, S; et al. Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. GENE 290:73-94(2002).