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POMT1

  • Official Full Name

    protein-O-mannosyltransferase 1

  • Synonyms

    RT; LGMD2K; MDDGA1; MDDGB1; MDDGC1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POMT1-1856H Recombinant Human POMT1, GST-tagged E.coli GST 285-595aa
Human POMT1-3762H Recombinant Human POMT1 Protein (Pro318-His513), N-His tagged E.coli N-His Pro318-His513
Mouse Pomt1-8035M Recombinant Mouse Pomt1 protein, His & T7-tagged E.coli His/T7 Pro318~His513 (Accession # Q8R2R1)
Rat POMT1-4576R Recombinant Rat POMT1 Protein Mammalian Cell His
Rat POMT1-4236R-B Recombinant Rat POMT1 Protein Pre-coupled Magnetic Beads HEK293
Rat POMT1-4236R Recombinant Rat POMT1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish POMT1-4448Z Recombinant Zebrafish POMT1 Mammalian Cell His
Chicken POMT1-2388C Recombinant Chicken POMT1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • POMT1 Related Articles

POMT1 involved in several pathways and played different roles in them. We selected most pathways POMT1 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Other types of O-glycan biosynthesisCHST10;MFNG;C3orf64;MGAT5B;B3GALTLB;POMT1;OGT;ST3GAL3B;FUT7

POMT1 has several biochemical functions, for example, contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activity, mannosyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POMT1 itself. We selected most functions POMT1 had, and list some proteins which have the same functions with POMT1. You can find most of the proteins on our site.

Function Related Protein
contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activityPOMT2;POMT1;SDF2L1
mannosyltransferase activityGTDC2;PIGZ;POMGNT2;DPY19L4;PIGV;ALG1;POMT1;B3GNT8;B3GNTL1
metal ion bindingOAS2;INPP5B;TUT1;ATF7B;NFS1;C6AST4;ZNF554;GFI1AA;SDHC

POMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POMT1.

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Endo, T; et al. Glycobiology of alpha-dystroglycan and muscular dystrophy. JOURNAL OF BIOCHEMISTRY 157:1-12(2015).
Haberlova, J; Mitrovic, Z; et al. Psycho-organic symptoms as early manifestation of adult onset POMT1-related limb girdle muscular dystrophy. NEUROMUSCULAR DISORDERS 24:990-992(2014).
  • Q&As
  • Reviews

Q&As (7)

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How do genetic variations in POMT1 affect muscle function and development? 10/15/2022

Genetic defects in POMT1 can lead to impaired muscle development and function, contributing to muscular dystrophies.

What potential therapeutic applications arise from targeting POMT1 in muscular dystrophies? 08/28/2022

Targeting POMT1 in therapy could provide new treatments for various forms of muscular dystrophy.

What is the impact of altered POMT1 activity on neuromuscular diseases? 08/02/2021

Altered POMT1 activity impacts the stability and function of muscle proteins, exacerbating neuromuscular diseases.

What role does POMT1 play in cell membrane integrity? 03/15/2021

POMT1 plays a role in maintaining cell membrane integrity, crucial for muscle and nerve cells.

How does POMT1 interact with other enzymes in the glycosylation pathway? 10/23/2020

POMT1 works with other glycosylation enzymes, playing a critical role in protein modification processes.

What is the primary role of POMT1 in protein glycosylation? 02/15/2018

POMT1 is involved in the O-mannosylation of proteins, an important type of glycosylation for protein function.

How does POMT1 contribute to muscular dystrophy disorders? 04/03/2017

Mutations in POMT1 are linked to certain types of muscular dystrophies, affecting muscle structure and function.

Customer Reviews (3)

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Reviews
02/25/2022

    Timely results. Accelerates our research timelines.

    11/18/2019

      Exceptional accuracy. Key to successful research.

      10/08/2017

        Reliable data source. A vital research asset.

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