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Porcn

Official Full Name

porcupine homolog (Drosophila)

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

HEK293
Insect Cell
Mammalian Cell

Tag

C
Flag
GFP
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PORCN-492HCL	Recombinant Human PORCN lysate	HEK293	N/A		Inquiry
Human	PORCN-0911H	Recombinant Human PORCN Protein (M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V), GFP-Flag tagged	Insect Cell	GFP-Flag	M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V	Inquiry
Human	PORCN-07H	Recombinant Human PORCN-TEV-GFP Protein (M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V), C-Flag-tagged	Insect Cell	C-Flag	M1-G461 end, remove 219-228aa, C187A, A194S, K231G, R232T, K233M, A234V	Inquiry
Mouse	PORCN-13131M	Recombinant Mouse PORCN Protein	Mammalian Cell	His		Inquiry
Mouse	PORCN-6947M	Recombinant Mouse PORCN Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PORCN-6947M-B	Recombinant Mouse PORCN Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PORCN-6768Z	Recombinant Zebrafish PORCN	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Porcn Related Articles

Porcn involved in several pathways and played different roles in them. We selected most pathways Porcn participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Porcn were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Wnt signaling pathway	PPP3CCA;WNT5B;INVS;SIAH1;FOSL1;WNT8A;NKD2B;FZD9B;NFATC2

Porcn has several biochemical functions, for example, Wnt-protein binding, palmitoleoyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Porcn itself. We selected most functions Porcn had, and list some proteins which have the same functions with Porcn. You can find most of the proteins on our site.

Function	Related Protein
Wnt-protein binding	EVLA;ROR1;FZD8B;SETD6;FZD9B;WLS;LRP2A;SFRP1A;FZD5
palmitoleoyltransferase activity

Porcn has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Porcn here. Most of them are supplied by our site. Hope this information will be useful for your research of Porcn.

Bankhead, EJ; Colasanto, MP; et al. Multiple Requirements of the Focal Dermal Hypoplasia Gene Porcupine during Ocular Morphogenesis. AMERICAN JOURNAL OF PATHOLOGY 185:197-213(2015).

Miranda, M; Galli, LM; et al. Identification of the WNT1 residues required for palmitoylation by Porcupine. FEBS LETTERS 588:4815-4824(2014).