POU2F1
-
Official Full Name
POU class 2 homeobox 1
-
Overview
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 (PubMed 8314572)). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT. -
Synonyms
POU2F1; POU class 2 homeobox 1; OTF1, POU domain class 2, transcription factor 1; POU domain, class 2, transcription factor 1; OCT1; NF-A1; OTF-1; oct-1; octamer-binding protein 1; Octamer-binding transcription factor-1; octamer-binding transcription factor 1; OTF1; oct-1B; FLJ42836;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- His|GST
- His|T7
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- POU2F1 Related Articles
- POU2F1 Related Research Area
POU2F1 involved in several pathways and played different roles in them. We selected most pathways POU2F1 participated on our site, such as ATF-2 transcription factor network, Calcineurin-regulated NFAT-dependent transcription in lymphocytes, Calcium signaling in the CD4+ TCR pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with POU2F1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| ATF-2 transcription factor network | HRK;DUSP1;DUSP5;KAT5;JDP2;MAPK14;JUNB;DUSP10;JUN |
| Calcineurin-regulated NFAT-dependent transcription in lymphocytes | EGR3;EGR2;EGR4;CDK4;IRF4;IKZF1;BATF3;EGR1;JUNB |
| Calcium signaling in the CD4+ TCR pathway | FKBP1A;BATF3;CSF2;CHP;JUNB;RCAN1;AKAP5;POU2F1;RCAN2 |
| FOXA1 transcription factor network | AP1B1;TFF1;NR2F2;POU2F1;FOXA1;NFIA;CEBPB;DSCAM;NFIC |
| Gene Expression | HNRNPL2;CCAR1;ZNF256;NR1D2;CPSF4;LRPPRC;FAM98B;ZNF680;NRBF2 |
| Glucocorticoid receptor regulatory network | KRT14;NR1I3;CSN2;SMARCA4;POU2F1;KRT17;SMARCC2;BGLAP;EGR1 |
| RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription | GATAD2A;CBX3A;SNAPC4;CBX3;PTRFB;CRCP;SNAPC5;BRF2;NFIC |
| RNA Polymerase III Abortive And Retractive Initiation | GTF3C5;NFIC;SNAPC4;ZNF143;CRCP;GTF3C4;NFIA;NFIX;GTF3C3 |
POU2F1 has several biochemical functions, for example, chromatin binding, protein binding, receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POU2F1 itself. We selected most functions POU2F1 had, and list some proteins which have the same functions with POU2F1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| chromatin binding | HDGFRP2;OVOL2;CHD7;FOXC1A;KIAA0101;NKX2;TFAM;CHAF1A;HINFP |
| protein binding | TREML1;SPOPL;HIST1H4B;ROCK1;S1PR3;PHOSPHO2-KLHL23;FAM124A;RPS25;DRD2 |
| receptor binding | HRG;ADM;SSFA2;FRK;SLC9A3R2;NTF3;TRDN;GDNF;UTS2 |
| sequence-specific DNA binding | MEF2A;RXRAB;RAG1;HOXB6;HOXB6A;IRX6A;ZNF35;PPARDB;BARHL1A |
| transcription factor activity, sequence-specific DNA binding | ELF2A;THRB;ESR2B;GM239;CNOT7;HIF1AB;SOX7;GATA3;POUV |
| transcription regulatory region sequence-specific DNA binding | SUV39H1;FOXN1;NFE2;KCNA3;SOX4;NFE2L3;BAHD1;BTBD8;POU5F1 |
POU2F1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU2F1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU2F1.
SP1; SP4; POGZ; PLK3; TEAD1; rta_ebvb9
- Q&As
- Reviews
Ask a Question for All POU2F1 Products
Required fields are marked with *
My Review for All POU2F1 Products
Required fields are marked with *
