PPID
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Official Full Name
Peptidylprolyl Isomerase D
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Overview
The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein has been shown to possess PPIase activity and, similar to other family members, can bind to the immunosuppressant cyclosporin A. -
Synonyms
PPID; CYPD; CYP-40; peptidyl-prolyl cis-trans isomerase D; OTTHUMP00000220869; peptidylprolyl isomerase D; PPIase D; Rotamase D; cyclophilin-40; cyclophilin D; cyclophilin 40; EC 5.2.1.8; peptidylprolyl isomerase D (cyclophilin D); cyclophilin-related protein; MGC33096; 40 kDa peptidyl-prolyl cis-trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS) (Acyrthosiphon pisum symbiotic bacterium)
- Escherichia coli (strain K12)
- Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
- Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)
- Human
- Mouse
- Pseudomonas aeruginosa
- Rat
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Mammalian Cell
- C
- His
- His (Fc)
- Avi
- His|T7
- Myc
- DDK
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
PPID involved in several pathways and played different roles in them. We selected most pathways PPID participated on our site, such as C-MYB transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPID were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| C-MYB transcription factor network | PRTN3;CEBPB;CEBPA;CBX4;GATA1;CDK6;MYF6;SKI;PTCRA |
PPID has several biochemical functions, for example, Hsp70 protein binding, Hsp90 protein binding, cyclosporin A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPID itself. We selected most functions PPID had, and list some proteins which have the same functions with PPID. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| Hsp70 protein binding | ST13;STIP1;GPR37;CDK1;FAM119A;DNAJC2;ERN1;L7RN6;METTL21A |
| Hsp90 protein binding | STUB1;UNC45A;NASP;USP19;ERBB2;ERN1;AHR;PACRG;RPS3 |
| cyclosporin A binding | PPIG;PPIE;PPIC;PPIH;PPIF;PPID |
| estrogen receptor binding | PADI2;WIPI1;LEF1;MED1;TMEM38A;PRMT2;PPARGC1B;NKX3;DDX5 |
| heat shock protein binding | FKBP5;DMPK;HDAC2;HSPA6;KCNJ11;IRAK1;BAK1;PPP5C;DNAJA2 |
| peptidyl-prolyl cis-trans isomerase activity | PPIFB;PPP2R4;PIN4;FKBP10B;PPID;RANBP2;PPIL6;PPIL4;FKBP1AA |
| protein binding | FRS2;PLSCR4;NFKB1;ACACB;SFPI1;PPIL1;MAPK8;IKBKG;RPS7 |
| transcription factor binding | KAT6B;PAXBP1;TRIM6;KAT8;DAXX;PRKDC;MED6;FIGLA;KDM1A |
PPID has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPID here. Most of them are supplied by our site. Hope this information will be useful for your research of PPID.
XRCC6; RPS3; GNB2L1; ILF2; MYB; KAT7; PLK1
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