ppip5k1
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  • Official Full Name
  • diphosphoinositol pentakisphosphate kinase 1
  • Background
  • This gene encodes a dual functional inositol kinase. The encoded enzyme converts inositol hexakisphosphate to diphosphoinositol pentakisphosphate and diphosphoinositol pentakisphosphate to bis-diphosphoinositol tetrakisphosphate. This protein may be important for intracellular signaling pathways. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 15.
  • Synonyms
  • PPIP5K1; diphosphoinositol pentakisphosphate kinase 1; HISPPD2A, histidine acid phosphatase domain containing 2A; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1; IPS1; KIAA0377; VIP1; IP6K; Histidine acid phosphatase domain-containing protein 2A; hsVIP1; Inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinase 1; Inositol pyrophosphate synthase 1; InsP6 and PP IP5 kinase 1; IP6 kinase; PP IP5 kinase 1; VIP1 homolog; insP6 and PP-IP5 kinase 1; histidine acid phosphatase domain containing 2A; HISPPD2A
Cat.#:PPIP5K1-13788HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIP5K1, His-tagged
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Cat.#:PPIP5K1-13192MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPIP5K1 Protein
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Cat.#:PPIP5K1-793HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPIP5K1 cell lysate
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Involved Pathway

PPIP5K1 involved in several pathways and played different roles in them. We selected most pathways PPIP5K1 participated on our site, such as Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIP5K1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phosphatidylinositol signaling system
PLCG2; PLCB4; MTMR3; PIP5K1A; ITPK1A; PTENA; ITPR1; CALML5; CALM3A; PIP5K1B

Protein Function

PPIP5K1 has several biochemical functions, for example, ATP binding, acid phosphatase activity, diphosphoinositol-pentakisphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIP5K1 itself. We selected most functions PPIP5K1 had, and list some proteins which have the same functions with PPIP5K1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ABCA7; DDX39AA; DNA2; ATP13A5; UBE2G1A; RARS; DGKE; BMPR1A; ACLY; DDR2
Function acid phosphatase activity
Related Protein ACP5B; PAPL; MINPP1A; PXYLP1; PPIP5K1; ACP5A; ACP5; ACP2; PPIP5K2; MINPP1
Function diphosphoinositol-pentakisphosphate kinase activity
Related Protein PPIP5K1; PPIP5K2
Function inositol hexakisphosphate 1-kinase activity
Related Protein IP6K2; PPIP5K2; IP6K1; IP6K3; PPIP5K1
Function inositol hexakisphosphate 3-kinase activity
Related Protein PPIP5K1; IP6K3; PPIP5K2; IP6K1; IP6K2
Function inositol hexakisphosphate 5-kinase activity
Related Protein IP6K2; PPIP5K2; IP6K1; IP6K3; PPIP5K1
Function inositol-1,3,4,5,6-pentakisphosphate kinase activity
Related Protein PPIP5K1

PPIP5K1 Related Articles

Williams, SP; Gillaspy, GE; et al. Biosynthesis and possible functions of inositol pyrophosphates in plants. FRONTIERS IN PLANT SCIENCE 6:-(2015).
Desai, M; Rangarajan, P; et al. Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants. PLANT JOURNAL 80:642-653(2014).