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PPT2

Official Full Name

palmitoyl-protein thioesterase 2
Overview

This gene encodes a member of the palmitoyl-protein thioesterase family. The encoded glycosylated lysosomal protein has palmitoyl-CoA hydrolase activity in vitro, but does not hydrolyze palmitate from cysteine residues in proteins. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream EGFL8 (EGF-like-domain, multiple 8) gene.
Synonyms

PPT2; palmitoyl-protein thioesterase 2; lysosomal thioesterase PPT2; C6orf8; Palmitoyl protein hydrolase 2; Palmitoyl protein thioesterase 2; PPT 2; S thioesterase G14; VE statin2; VE-statin2; S-thioesterase G14; palmitoyl-protein hydrolase 2; G14; PPT-2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Oryza sativa subsp. japonica (Rice)
Rat
Zebrafish

Source

E.coli
E.coli expression system
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPT2-1930H	Recombinant Human PPT2, His-tagged	E.coli	His	1-302aa	$319 / 25ug
Human	PPT2-2905HCL	Recombinant Human PPT2 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	PPT2-13282M	Recombinant Mouse PPT2 Protein	Mammalian Cell	His		Inquiry
Mouse	PPT2-7051M	Recombinant Mouse PPT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PPT2-7051M-B	Recombinant Mouse PPT2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	PPT2-4648R	Recombinant Rat PPT2 Protein	Mammalian Cell	His		Inquiry
Rat	PPT2-4307R-B	Recombinant Rat PPT2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	PPT2-4307R	Recombinant Rat PPT2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Oryza sativa subsp. japonica (Rice)	RFL33947OF	Recombinant Full Length Oryza Sativa Subsp. Japonica Phosphoenolpyruvate/Phosphate Translocator 2, Chloroplastic(Ppt2) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (52-407)	Inquiry
Zebrafish	PPT2-6077Z	Recombinant Zebrafish PPT2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PPT2 involved in several pathways and played different roles in them. We selected most pathways PPT2 participated on our site, such as Fatty acid elongation, Metabolic pathways, Fatty acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Fatty acid elongation	ELOVL7;ACOT2;PTPLAD1;ELOVL5;ELOVL1;ELOVL4A;HSD17B12A;ELOVL4B;HADH
Metabolic pathways	ATP5D;UGT1A2;DCXR;UGT8A;GCDHB;GMPPB;CYP27B1;URAD;RFK
Fatty acid metabolism	ACSL1;EHHADH;ACAA1A;ACAT1;ACADM;PECR;ACOX3;PPT1;TECRB
Lysosome	ACP5A;CLTCB;LAPTM5;IDUA;ATP6V0A1;CTSH;SMPD1;AP1S3;AP3B1

PPT2 has several biochemical functions, for example, palmitoyl hydrolase activity, palmitoyl-(protein) hydrolase activity, thiolester hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPT2 itself. We selected most functions PPT2 had, and list some proteins which have the same functions with PPT2. You can find most of the proteins on our site.

Function	Related Protein
palmitoyl hydrolase activity
palmitoyl-(protein) hydrolase activity	LYPLAL1;LYPLA1;LYPLA2;PPT1;PPT2
thiolester hydrolase activity	ALDH6A1;Acnat1;ACNAT2;PPT2;UFSP1;UFSP2;ACOT5

PPT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPT2.