psma1
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  • Official Full Name
  • proteasome (prosome, macropain) subunit, alpha type, 1
  • Background
  • The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
  • Synonyms
  • PSMA1; proteasome (prosome, macropain) subunit, alpha type, 1; proteasome subunit alpha type-1; HC2; MGC1667; MGC14542; MGC14575; MGC14751; MGC21459; MGC22853; MGC23915; NU; PROS30; 30 kDa prosomal protein; HC 2; Macropain subunit C2; Macropain subunit nu; Multicatalytic endopeptidase complex subunit C2; PROS 30; PROS-30; Proteasome (prosome macropain) subunit alpha type 1; Proteasome alpha 1 subunit; Proteasome component C2; Proteasome nu chain; Proteasome subunit alpha type 1; Proteasome subunit alpha type I; Proteasome subunit nu; Protein P30 33K; PSA1_HUMAN; PSC 2; PSC2; PSMA 1; protein P30-33K; OTTHUMP00000231103; OTTHUMP00000237995; OTTHUMP00000237996; proteasome
Cat.#:PSMA1-2652STag:His-sumostar
Source (Host):YeastSpecies:Staphylococcus Aureus
Product nameRecombinant Staphylococcus Aureus PSMA1 Protein (1-21 aa), His-sumostar-tagged
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Cat.#:PSMA1-2009HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA1, GST-tagged
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Cat.#:PSMA1-30393THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA1
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Cat.#:PSMA1-30394THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA1, His-tagged
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Cat.#:PSMA1-661HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA1 Protein, His-tagged
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Cat.#:PSMA1-6883HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Proteasome (prosome, macropain) Subunit, Alpha Type, 1, His-tagged
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Cat.#:PSMA1-839HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PSMA1, T7-tagged
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Cat.#:PSMA1-4762RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PSMA1 Protein
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Cat.#:PSMA1-817CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PSMA1 Protein, His-tagged
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Cat.#:PSMA1-3647RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PSMA1 Protein, His-tagged
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Cat.#:PSMA1-6577CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PSMA1
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Cat.#:PSMA1-879ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PSMA1
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Cat.#:PSMA1-2780HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PSMA1 293 Cell Lysate
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Involved Pathway

PSMA1 involved in several pathways and played different roles in them. We selected most pathways PSMA1 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Proteasome
PSMA4; PSMD12; PSMD11B; PSMB11; PSME2; PSMD8; PSMB9A; PSMC1A; PSMA6; PSMB6

Protein Function

PSMA1 has several biochemical functions, for example, RNA binding, endopeptidase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMA1 itself. We selected most functions PSMA1 had, and list some proteins which have the same functions with PSMA1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA binding
Related Protein RCL1; ILF3; U2AF2B; ENDOU2; EIF3B; IMPDH1; YY1; PTBP1; NOL9; HUG
Function endopeptidase activity
Related Protein PSMB8F; ADAMTS3; HTRA3; ELANE; KLK1B11; ADAM10; KLK1B22; CTSH; RHBDD1; PSMA7
Function protein binding
Related Protein KAT8; ASPA; ELANE; ZMYM2; REEP1; RERE; RRAS2; KIAA1524; HELLS; KPNA6
Function threonine-type endopeptidase activity
Related Protein PSMA6B; PSMA4; PSMA3; PSMB9A; PSMA8; PSMA2; PSMB8F; PSMB5; PSMB11; PSMA5

Interacting Protein

PSMA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMA1.
PSMA7; PSMA3; PSMA2