ptbp2
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  • Official Full Name
  • polypyrimidine tract binding protein 2
  • Background
  • The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract binding protein but it is expressed primarily in the brain.
  • Synonyms
  • PTBP2; polypyrimidine tract binding protein 2; polypyrimidine tract-binding protein 2; brPTB; nPTB; PTB; PTBLP; PTB-like protein; splicing regulator; neurally-enriched homolog of PTB; neural polypyrimidine tract binding protein; neural polypyrimidine trac
Cat.#:PTBP2-83HTag:His
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human PTBP2 protein, His-tagged
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Cat.#:PTBP2-13621MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PTBP2 Protein
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Cat.#:PTBP2-4796RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PTBP2 Protein
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Cat.#:PTBP2-2727HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PTBP2 293 Cell Lysate
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Involved Pathway

PTBP2 involved in several pathways and played different roles in them. We selected most pathways PTBP2 participated on our site, such as mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTBP2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
mRNA processing
HNRNPL; MCTS2; DDX20; SFPQ; SRPK2; NONO; DDX39; SNURF; SF3B4; ZFP346

Protein Function

PTBP2 has several biochemical functions, for example, mRNA binding, nucleotide binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTBP2 itself. We selected most functions PTBP2 had, and list some proteins which have the same functions with PTBP2. You can find most of the proteins on our site.
Function
Related Protein
Function mRNA binding
Related Protein RBFOX1; MRPS7; LIN28A; ITM2B; ELAVL1; DXO; RBM38; TRA2B; EIF4A1; FMR1
Function nucleotide binding
Related Protein KIF3CB; LRGUK; ADCY1A; CSTF2T; PEO1; PDXK; ARL3L1; ARF3A; HNRNPR; ARL8BA
Function poly(A) RNA binding
Related Protein DDX5; MRPS21; CPEB2; NOP58; RPN1; DARS; MRPS24; EIF4ENIF1; TSFM; MRPL28

Interacting Protein

PTBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTBP2.
RBM10; QKI; TOM1; KHDRBS3; HNRNPC; SNRPA; MATR3; PCBP3; KHDRBS1; GOLGA2; CALCOCO2; HNRNPD; ELAVL1; HNRNPAB; RBM4; EIF5A2; PUF60