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PTPRQ

Official Full Name

protein tyrosine phosphatase, receptor type, Q
Overview

This locus encodes a member of the type III receptor-like protein-tyrosine phosphatase family. The encoded protein;catalyzes the dephosphorylation of phosphotyrosine and phosphatidylinositol and plays roles in cellular proliferation;and differentiation. Mutations at this locus are associated with hearing loss.
Synonyms

PTPRQ; protein tyrosine phosphatase, receptor type, Q; deafness, autosomal recessive 84 , DFNB84; phosphotidylinositol phosphatase PTPRQ; Protein tyrosine phosphatase RQ; PTPGMC1; PTP-RQ; R-PTP-Q; receptor-type tyrosine-protein phosphatase Q; protein-tyrosine phosphatase, receptor-type, expressed by glomerular mesangial cells; DFNB84;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
His|T7

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PTPRQ-8107H	Recombinant Human PTPRQ protein, His & T7-tagged	E.coli	His/T7	Glu36~Thr294 (Accession # Q9UMZ3)	Inquiry
Mouse	PTPRQ-13705M	Recombinant Mouse PTPRQ Protein	Mammalian Cell	His		Inquiry
Mouse	PTPRQ-7290M-B	Recombinant Mouse PTPRQ Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	PTPRQ-7290M	Recombinant Mouse PTPRQ Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PTPRQ-4843R	Recombinant Rat PTPRQ Protein	Mammalian Cell	His		Inquiry
Rat	PTPRQ-4502R-B	Recombinant Rat PTPRQ Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	PTPRQ-4502R	Recombinant Rat PTPRQ Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PTPRQ involved in several pathways and played different roles in them. We selected most pathways PTPRQ participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPRQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

PTPRQ has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity, IDP phosphatase activity, JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPRQ itself. We selected most functions PTPRQ had, and list some proteins which have the same functions with PTPRQ. You can find most of the proteins on our site.

Function	Related Protein
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	SACM1L;PTPRQ;CTDSPL2A;SACM1LB;SGPP2;SACM1LA;TENC1;CTDSPL2B;NT5DC3
IDP phosphatase activity	TENC1;CTDSPL2A;SGPP2;CTDSPL2B;SACM1L;SACM1LA;PTPRQ;PXYLP1;NT5DC3
JUN kinase phosphatase activity	CTDSPL2A;PTPRQ;NT5DC3;CTDSPL2B;SACM1LB;SACM1L;DUSP19;PXYLP1;TENC1
MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP2;DUSP8A;DUSP7;DUSP10;NT5DC3;SACM1L;SACM1LB;DUSP9;CTDSPL2A
NADP phosphatase activity	TENC1;CTDSPL2B;SGPP2;SACM1LB;NT5DC3;PTPRQ;PXYLP1;SACM1LA;CTDSPL2A
hydrolase activity	ATP1A3A;MEP1A.1;SSH2B;NUDT3B;NCEH1A;CNOT6L;PXYLP1;HRASLS;MMP25
inositol bisphosphate phosphatase activity	TENC1;PTPRQ;CTDSPL2A;PXYLP1;NT5DC3;CTDSPL2B;INPP5K;SACM1LB;SACM1L
inositol phosphate phosphatase activity	CTDSPL2A;CTDSPL2B;SGPP2;SACM1LA;TENC1;SACM1L;NT5DC3;PTPRQ;PXYLP1
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	SACM1LA;SACM1LB;TENC1;PXYLP1;NT5DC3;CTDSPL2B;ITPK1;SGPP2;CTDSPL2A
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	PTPRQ;CTDSPL2B;SACM1L;NT5DC3;SACM1LA;PXYLP1;SACM1LB;SGPP2;TENC1
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	TENC1;NT5DC3;PXYLP1;SACM1L;SACM1LB;SGPP2;ITPK1;SACM1LA;CTDSPL2B
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	PTPRQ;TENC1;SACM1LA;SACM1LB;CTDSPL2A;NT5DC3;SACM1L;ITPK1;SGPP2
inositol-1,3,4-trisphosphate 1-phosphatase activity	INPP1;SGPP2;SACM1L;TENC1;PXYLP1;CTDSPL2B;CTDSPL2A;SACM1LB;NT5DC3
inositol-1,3,4-trisphosphate 4-phosphatase activity	NT5DC3;PTPRQ;SGPP2;SACM1LA;CTDSPL2B;TENC1;CTDSPL2A;SACM1LB;SACM1L
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	SGPP2;CTDSPL2B;PXYLP1;SACM1LA;CTDSPL2A;NT5DC3;PTPRQ;SACM1LB;TENC1
inositol-3,4-bisphosphate 4-phosphatase activity	TENC1;CTDSPL2A;PXYLP1;NT5DC3;SACM1L;SACM1LB;PTPRQ;SGPP2;SACM1LA
inositol-4,5-bisphosphate 5-phosphatase activity	TENC1;PTPRQ;NT5DC3;SGPP2;PXYLP1;SACM1LA;CTDSPL2B;CTDSPL2A;SACM1LB
phosphatase activity	PTP4A2A;PHOSPHO1;PTP4A2B;DUSP23B;PTPN20;ACPP;PPP1CC;SACM1LA;DUSP19A
phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	SACM1LA;CTDSPL2B;SACM1LB;CTDSPL2A;NT5DC3;SACM1L;TENC1;PTPRQ;SGPP2
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	PXYLP1;MTMR1B;MTMR3;SACM1L;MTMR1;SACM1LB;TENC1;MTMR2;SACM1LA
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	NT5DC3;FIG4;SACM1LA;PXYLP1;TENC1;PTPRQ;CTDSPL2A;SGPP2;PIKFYVE
phosphatidylinositol-4-phosphate phosphatase activity	SGPP2;CTDSPL2B;SACM1LB;PTPRQ;TENC1;SACM1L;FIG4;PXYLP1;NT5DC3
phosphohistidine phosphatase activity	CTDSPL2B;SACM1LB;CTDSPL2A;PXYLP1;PTPRQ;MINPP1;SACM1LA;SACM1L;PHPT1
phosphoprotein phosphatase activity	SSH2;CDC14A;TENC1;PPP3CB;CDC14AA;PPP2CA;ACP2;PTPN11B;PTPN23A
protein tyrosine phosphatase activity	LRP8;PTPRM;PTPRNA;DUSP6;PTPN4B;PGP;CDC25A;DUSP12;KIAA1274
protein tyrosine/serine/threonine phosphatase activity	DUSP13;DUSP8A;MTMR2;DUSP3B;DUSP3;SACM1LA;PTP4A2B;CDC14B;DUSP12
protein tyrosine/threonine phosphatase activity	SGPP2;DUSP4;DUSP19;TENC1;SACM1LB;CTDSPL2A;SACM1LA;DUSP1;DUSP2
transmembrane receptor protein phosphatase activity	NT5DC3;SACM1L;CTDSPL2B;PXYLP1;SACM1LB;TENC1;PTPRQ;SACM1LA;CTDSPL2A

PTPRQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPRQ here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPRQ.