Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

PDE1A

  • Official Full Name

    PDE1A phosphodiesterase 1A, calmodulin-dependent

  • Overview

    Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic;nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime;monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent;PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 (PubMed 11342109);;Fidock et al., 2002 (PubMed 11747989)).
  • Synonyms

    PDE1A; phosphodiesterase 1A, calmodulin-dependent; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1A; hCam-1; cam-PDE 1A; 61 kDa Cam-PDE; phosphodiesterase-1A; calmodulin-dependent phosphodiesterase; 3,5 cyclic nucleotide phosphodiesterase; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; HCAM1; HSPDE1A; MGC26303;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Flag
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDE1A-29692TH Recombinant Human PDE1A N/A
Human PDE1A-333H Recombinant Human PDE1A Mammalian Cell His
Human PDE1A-471H Recombinant Human PDE1A, His-tagged, Active Sf9 Insect Cell His
Human PDE1A-3353HCL Recombinant Human PDE1A 293 Cell Lysate HEK293 N/A
Human PDE1A-1630H Recombinant Human PDE1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PDE1A-300H Recombinant Human PDE1A Protein, His-tagged E.coli His Gly2~Asp318
Human PDE1A-1630H-B Recombinant Human PDE1A Protein Pre-coupled Magnetic Beads HEK293
Human PDE1A-1787H Recombinant Human PDE1A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDE1A-779HFL Recombinant Full Length Human PDE1A Protein, C-Flag-tagged Mammalian cells Flag
Mouse Pde1a-4742M Recombinant Mouse Pde1a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque PDE1A-3345R Recombinant Rhesus monkey PDE1A Protein, His-tagged Mammalian Cell His
Rhesus Macaque PDE1A-3163R Recombinant Rhesus Macaque PDE1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PDE1A-3163R-B Recombinant Rhesus Macaque PDE1A Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PDE1A Related Articles

PDE1A involved in several pathways and played different roles in them. We selected most pathways PDE1A participated on our site, such as Purine metabolism, Calcium signaling pathway, Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismATIC;NT5C2A;HPRT1;PDE6C;CANT1A;ENTPD8;POLR3K;POLR3D;ADAL
Calcium signaling pathwayGRIN2A;P2RX8;PRKCG;P2RX7;PPP3CB;TNNC1B;PLCB4;HTR5A;CHRM5B
Olfactory transductionOLFR1038-PS;OR4C12;OR51B4;OLFR1440;OR51B2;SLC24A4;CAMK2D;OR4D2;OLFR147
Taste transductionTAS1R1;GNB1;TAS2R113;GNAT3;TAS2R13;GNAS;TAS2R125;TAS2R20;ASIC2
Renin secretionCALM3;CLCA3;AGTR1B;ORAI1;GNAI1;PDE3B;PRKG2;CLCA2;CALM4

PDE1A has several biochemical functions, for example, calmodulin binding, calmodulin-dependent cyclic-nucleotide phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE1A itself. We selected most functions PDE1A had, and list some proteins which have the same functions with PDE1A. You can find most of the proteins on our site.

Function Related Protein
calmodulin bindingPPP3R1;PDE1A;MYH7;CAMK2B1;DAPK2;SCN5A;MYH10;MAP2;ENKUR
calmodulin-dependent cyclic-nucleotide phosphodiesterase activityPDE1B;PDE1C;PDE1A;USB1;TDP2B
metal ion bindingPPM1BB;CYP2K22;ZKSCAN14;PRLR;TSNAX;ZNF740;CPSF3;ZNF830;HINFP

PDE1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE1A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE1A.

YWHAZ

Matsumoto, C; Ito, M; et al. Genes that characterize T-3-predominant Graves' thyroid tissues. EUROPEAN JOURNAL OF ENDOCRINOLOGY 168:137-144(2013).
Santone, R; Giorgi, M; et al. Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina. JOURNAL OF NEUROSCIENCE RESEARCH 84:1020-1026(2006).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PDE1A Products

Required fields are marked with *

My Review for All PDE1A Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends