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PDGFC

  • Official Full Name

    platelet derived growth factor C

  • Overview

    The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    PDGFC; platelet derived growth factor C; platelet-derived growth factor C; fallotein; SCDGF; PDGF-C; VEGF-E; spinal cord-derived growth factor; secretory growth factor-like protein; AI647969; 1110064L01Rik;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • E. coli
  • E.coli
  • HEK293
  • Human Cell
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • Yeast
  • Fc
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Met|His
  • N/A
  • N
  • hFc
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDGFC-208H Active Recombinant Human PDGFC, His-tagged E.coli His
Human PDGFC-699H Active Recombinant Human PDGFC Protein, Met & His-tagged E.coli Met/His Val235-Gly345
Human PDGFC-888H Recombinant Human PDGFC Mammalian Cell His
Human PDGFC-441H Recombinant Human Platelet Derived Growth Factor C E.coli N/A
Human PDGFC-206H Active Recombinant Human PDGFC protein(Val235-Gly345), hFc-tagged HEK293 N-hFc Val235-Gly345
Human PDGFC-7280H Recombinant Human PDGFC protein, His-tagged Insect Cells His Val235-Gly345
Human PDGFC-429HCL Recombinant Human PDGFC cell lysate Insect Cell N/A
Human PDGFC-2872HCL Recombinant Human PDGFC cell lysate Human Cell N/A
Human PDGFC-517H Recombinant Human PDGFC Protein, His-tagged Yeast His Val235-Gly345
Human PDGFC-096H Active Recombinant Human PDGFC Protein E. coli
Human PDGFC-3821H-B Recombinant Human PDGFC Protein Pre-coupled Magnetic Beads HEK293
Human PDGFC-167P Active Recombinant Human PDGFCC Protein HEK293
Human PDGFC-5000H Recombinant Human PDGFC Protein (Val235-Gly345), N-His tagged E.coli N-His Val235-Gly345
Human PDGFC-3821H Recombinant Human PDGFC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pdgfc-873M Active Recombinant Mouse Pdgfc protein(Val235-Gly345), hFc-tagged HEK293 N-hFc Val235-Gly345
Mouse Pdgfc-8158M Recombinant Mouse Pdgfc protein, His & T7-tagged E.coli His/T7 Glu23~Gly345 (Accession# Q8CI19)
Mouse PDGFC-1836MCL Recombinant Mouse PDGFC cell lysate Human Cell N/A
Mouse Pdgfc-1073M Recombinant Mouse Pdgfc protein(Val235-Gly345), His-tagged Yeast N-His Val235-Gly345
Mouse PDGFC-518M Recombinant Mouse Pdgfc Protein, His-tagged Yeast His Val235-Gly345
Rat PDGFC-4338R Recombinant Rat PDGFC Protein Mammalian Cell His
Rat PDGFC-3998R Recombinant Rat PDGFC Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PDGFC-3998R-B Recombinant Rat PDGFC Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PDGFC-1174C Active Recombinant Cynomolgus PDGFC Protein, Fc-tagged HEK293 Fc
Chicken PDGFC-6286C Recombinant Chicken PDGFC Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PDGFC involved in several pathways and played different roles in them. We selected most pathways PDGFC participated on our site, such as Ras signaling pathway, Rap signaling pathway, Cytokine-cytokine receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDGFC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwayRAP1A;PAK7;GNB3;RAB5B;PAK3;PLA2G12A;TEK;BCL2L1;GNG3
Rap signaling pathwayHRAS;RAP1B;MAPK11;LPAR3;ITGB2L;MAPK3;RAC1;PFN3;PDGFRB
Cytokine-cytokine receptor interactionVEGFB;NGFR;TNFB;IL20RA;IL17A;GM2002;IL19;KITA;CCL19B
Phospholipase D signaling pathwayPIK3R2;FYN;Pdgfa&Pdgfb;PLCB3;MAP2K1;AGTR1B;PLCG2;AKT1;GRM6
PIK-Akt signaling pathwayGh;FGF22;PIK3CB;FGF14;MAP2K2;TNR;YWHAE;IFNA17;GYS2
Focal adhesionPRKCG;COL27A1A;RHOA;PIK3CG;VAV3B;PPP1R12C;COL2A1B;SRC;ACTN2B
Gap junctionADRB3B;GNA15.4;PRKCA;MAP3K2;Pdgfa&Pdgfb;ADRB3A;PDGFA;RAF1B;GNA11
Regulation of actin cytoskeletonINS;PIKFYVE;GNG12A;PIK3R2;FGD;BDKRB2;MSN;PIK3CD;ITGA10
Prostate cancerGSK3B;MAP2K1;PIK3R3;NDRG1;CREB3L3;PIK3R1;HRAS;SOS1;TP53
MelanomaAKT2;MAPK3;FGF14;MAP2K1;PIK3R2;PIK3R5;PDGFRB;PDGFRA;FGF22
Choline metabolism in cancerMAPK8;PLD1;PDGFB;DGKE;PLD2;WASF2;PPAP2B;RAC3;PDGFRA

PDGFC has several biochemical functions, for example, growth factor activity, platelet-derived growth factor receptor binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFC itself. We selected most functions PDGFC had, and list some proteins which have the same functions with PDGFC. You can find most of the proteins on our site.

Function Related Protein
growth factor activityIL34;MSTN;FGF9;IGF2;EREG;IL11;CSF1;NDR1;VHL
platelet-derived growth factor receptor bindingFIGF;ITGB3;PDGFAA;PDGFRB;VEGFA;LYN;Pdgfa&Pdgfb;PDGFB;PDGFRA
protein bindingRBP5;USH1C;ZNF423;PLIN3;DYRK1A;THRB;EIF4E;MAPK9;ZC3H11A
protein homodimerization activityID1;BCL2;CUBN;MYOM3;GNPTG;DMBX1;UGT1A2;BMPR1A;TMEM192

PDGFC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFC here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFC.

PDGFRA

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