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Pigf

  • Official Full Name

    phosphatidylinositol glycan anchor biosynthesis, class F

  • Overview

    This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms

    PIGF; phosphatidylinositol glycan anchor biosynthesis, class F; phosphatidylinositol glycan, class F; phosphatidylinositol-glycan biosynthesis class F protein; PIG-F; GPI11 homolog; MGC32646; MGC33136;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • Fc
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human VEGFA&PIGF-28H Active Recombinant human VEGF/PlGF E.coli N/A
Human PIGF-464H Recombinant Human PIGF Mammalian Cell His
Human PIGF-456H Recombinant Human PIGF HEK293 N/A
Human PIGF-1123H Active Recombinant Human PIGF Protein, Fc-tagged HEK293 Fc
Human PIGF-3854H Recombinant Human PIGF Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PIGF-3854H-B Recombinant Human PIGF Protein Pre-coupled Magnetic Beads HEK293
Mouse Pigf-330M Recombinant Mouse Pigf E.coli N/A
Mus musculus (Mouse) RFL30949MF Recombinant Full Length Mouse Phosphatidylinositol-Glycan Biosynthesis Class F Protein(Pigf) Protein, His-Tagged E.coli expression system His Full Length (1-219)
Zebrafish PIGF-11676Z Recombinant Zebrafish PIGF Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Pigf Related Articles

Pigf involved in several pathways and played different roles in them. We selected most pathways Pigf participated on our site, such as Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pigf were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycosylphosphatidylinositol(GPI)-anchor biosynthesisGPLD1;PIGYL;PIGS;PIGA;PIGN;PIGK;PIGQ;DPM2;PIGH
Metabolic pathwaysMECR;LASS2;ALOX12E;RPE;INPP5A;NT5C1B-RDH14;ST3GAL3B;KHK;SQLEA

Pigf has several biochemical functions, for example, ethanolaminephosphotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pigf itself. We selected most functions Pigf had, and list some proteins which have the same functions with Pigf. You can find most of the proteins on our site.

Function Related Protein
ethanolaminephosphotransferase activityEPT1;PIGF;CEPT1

Pigf has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pigf here. Most of them are supplied by our site. Hope this information will be useful for your research of Pigf.

Penson, RT; Moore, KM; et al. A phase II study of ramucirumab (IMC-1121B) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma. GYNECOLOGIC ONCOLOGY 134:478-485(2014).
Deissler, HL; Lang, GK; et al. Capacity of aflibercept to counteract VEGF-stimulated abnormal behavior of retinal microvascular endothelial cells. EXPERIMENTAL EYE RESEARCH 122:20-31(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
What are the clinical applications of PIGF protein? 10/26/2021

PIGF protein has various clinical applications in the fields of oncology, cardiology, and obstetrics.

How is PIGF protein used in oncology? 10/03/2018

In oncology, PIGF protein is used as a biomarker for certain types of cancer, aiding in diagnosis and prognosis.

What are the methods used to measure PIGF protein levels in clinical settings? 08/02/2018

Enzyme-linked immunosorbent assay (ELISA) and other immunoassay techniques are commonly used to measure PIGF protein levels.

How are abnormal PIGF protein levels linked to cancer progression? 06/24/2017

Increased PIGF protein levels are often associated with tumor growth, invasion, and metastasis in various types of cancer.

How is PIGF protein involved in the pathophysiology of preeclampsia? 01/28/2016

PIGF protein levels are reduced in women with preeclampsia, and its dysregulation is associated with the development of the condition.

Customer Reviews (3)

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Reviews
12/17/2022

    Its impressive purity and functional properties make it an ideal choice for my research, ensuring precise and accurate results.

    08/18/2021

      Their expertise and responsiveness exemplify their dedication to assisting customers, offering solutions and guidance whenever challenges arise.

      08/27/2017

        The combination of the protein's exceptional characteristics and the manufacturer's outstanding technical assistance equips me with the necessary resources to overcome potential hurdles and achieve groundbreaking results.

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