Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Polb

  • Official Full Name

    polymerase (DNA directed), beta

  • Overview

    The protein encoded by this gene is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. The encoded protein, acting as a monomer, is normally found in the cytoplasm, but it translocates to the nucleus upon DNA damage. Several transcript variants of this gene exist, but the full-length nature of only one has been described to date. [provided by RefSeq, Sep 2011]
  • Synonyms

    POLB; polymerase (DNA directed), beta; DNA polymerase beta; DNA pol beta; mutant DNA polymerase beta; DNA polymerase beta subunit;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • Mammalian Cell
  • C
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POLB-620H Recombinant Human Polymerase (DNA Directed), Beta E.coli N/A
Human POLB-621H Recombinant Human POLB protein N/A
Human POLB-1014H Recombinant Human POLB, His-tagged E. coli His
Human POLB-1521H Recombinant Human POLB protein E.coli N/A
Human POLB-524H Recombinant Human POLB protein E.coli N/A
Human POLB-1388HCL Recombinant Human POLB cell lysate N/A
Human POLB-2141H Recombinant Human POLB Protein (Ser2-Glu335), C-His tagged E.coli C-His Ser2-Glu335
Mouse POLB-13067M Recombinant Mouse POLB Protein Mammalian Cell His
Mouse POLB-6903M Recombinant Mouse POLB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse POLB-6903M-B Recombinant Mouse POLB Protein Pre-coupled Magnetic Beads HEK293
Rat Polb-766R Recombinant Rat Polymerase (DNA Directed), Beta E.coli N/A
Rat POLB-4561R Recombinant Rat POLB Protein Mammalian Cell His
Rat POLB-4221R Recombinant Rat POLB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat POLB-4221R-B Recombinant Rat POLB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque POLB-3503R Recombinant Rhesus monkey POLB Protein, His-tagged Mammalian Cell His
Rhesus Macaque POLB-3321R Recombinant Rhesus Macaque POLB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque POLB-3321R-B Recombinant Rhesus Macaque POLB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish POLB-1166Z Recombinant Zebrafish POLB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

Polb involved in several pathways and played different roles in them. We selected most pathways Polb participated on our site, such as Base excision repair, HTLV-I infection, Viral carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Polb were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Base excision repairPARP4;xthA;LIG3;POLE4;UNG;POLD2;HMGB1A;NEIL2;mutY
HTLV-I infectionPOLE;HLA-DQB1;HLA-B;SFPI1;TCF3;RELA;PRKACB;FZD8;WNT2B
Viral carcinogenesisGRB2;NFKB1;C3;HIST2H2BB;GTF2H4;CDC42;PIK3CG;HNRNPK;GTF2H1

Polb has several biochemical functions, for example, DNA-directed DNA polymerase activity, damaged DNA binding, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Polb itself. We selected most functions Polb had, and list some proteins which have the same functions with Polb. You can find most of the proteins on our site.

Function Related Protein
DNA-directed DNA polymerase activityPOLK;POLE3;POLL;PRIMPOL;POLA1;PAPD7;POLH;POLN;POLE4
damaged DNA bindingXRCC5;APTX;REV1;EP300;POLB;DCLRE1C;RPS3;RAD23AB;ERCC4
enzyme bindingHDAC2;SUDS3;DNM2;SNX12;DAOA;DHCR24;CYP2E1;POR;HSPA1A
lyase activityCRY5;AMD2;POLB;ALDOCB;TSEN34;CBSA;CAR13;Car4;GUCY2F
metal ion bindingNUDT14;MBTD1;DOM3Z;EXTL3;ZBTB18;IRF2BPL;PHF20B;ZNF526;GTF2E1
microtubule bindingGAPDH;MAP1LC3B;LRPPRC;NDEL1A;UXT;RPS3;ZFP207;KIF19;KIF1C
protein bindingZFP36;CTBP2;SCAF8;TSKS;IMPDH2;NCAPD2;KCTD13;MFF;HIST2H3C2

Polb has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Polb here. Most of them are supplied by our site. Hope this information will be useful for your research of Polb.

TPP2; XRCC1; TAF1D; SRPK2; KAT7; TLE1; ssdna_dadts; Ktn1; XRCC3; Junb

  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (1)

Write a review
Reviews
09/07/2023

    Efficacy: The enzyme is still active and I am currently using it in some DNA repair assays. It works very well for single nucleotide insertions in gapped DNA which is mostly what I have been using it for recently.
    Quality: Very happy with the quality and longevity. I think the enzyme is ~1yr old with frequent usage and it is still working fine.
    Overall Experience: Very happy. When we need more polB/hUNG, and potentially others, we will purchase from you again.

    Ask a Question for All Polb Products

    Required fields are marked with *

    My Review for All Polb Products

    Required fields are marked with *

    logo

    FOLLOW US

    Terms and Conditions        Privacy Policy

    Copyright © 2024 Creative BioMart. All Rights Reserved.

    Contact Us

    • /

    Stay Updated on the Latest Bioscience Trends