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PPP1R15A

  • Official Full Name

    protein phosphatase 1, regulatory subunit 15A

  • Overview

    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation.
  • Synonyms

    PPP1R15A; protein phosphatase 1, regulatory subunit 15A; protein phosphatase 1, regulatory (inhibitor) subunit 15A; protein phosphatase 1 regulatory subunit 15A; GADD34; growth arrest and DNA damage inducible 34; growth arrest and DNA-damage-inducible 34;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Yeast
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP1R15A-15H Recombinant Human PPP1R15A Protein, GST-tagged Wheat Germ GST
Human PPP1R15A-2943H Recombinant Human PPP1R15A protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PPP1R15A-2943HCL Recombinant Human PPP1R15A 293 Cell Lysate HEK293 N/A
Human PPP1R15A-1943H Recombinant Human PPP1R15A Protein (40-674 aa), His-tagged Yeast His 40-674 aa
Human PPP1R15A-4491H Recombinant Human PPP1R15A protein, His-tagged E.coli His 40-674aa
Human PPP1R15A-2441HFL Recombinant Full Length Human PPP1R15A protein, Flag-tagged Mamanlian cells Flag
Mouse Ppp1r15a-397M Recombinant Mouse Ppp1r15a Protein, His-tagged E.coli His Pro433~Thr636
Mouse Ppp1r15a-5064M Recombinant Mouse Ppp1r15a Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PPP1R15A-4619R Recombinant Rat PPP1R15A Protein Mammalian Cell His
Rat Ppp1r15a-398R Recombinant Rat Ppp1r15a Protein, His-tagged E.coli His Glu335~Gly578
Rat PPP1R15A-4278R-B Recombinant Rat PPP1R15A Protein Pre-coupled Magnetic Beads HEK293
Rat PPP1R15A-4278R Recombinant Rat PPP1R15A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PPP1R15A-5291Z Recombinant Zebrafish PPP1R15A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPP1R15A Related Articles

PPP1R15A involved in several pathways and played different roles in them. We selected most pathways PPP1R15A participated on our site, such as Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R15A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Protein processing in endoplasmic reticulumATF4;LMAN2;SSR4;BAG1;DNAJA2;UBE2D1;UBE4B;DERL1;HSPA6

PPP1R15A has several biochemical functions, for example, protein binding, protein kinase binding, protein phosphatase 1 binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R15A itself. We selected most functions PPP1R15A had, and list some proteins which have the same functions with PPP1R15A. You can find most of the proteins on our site.

Function Related Protein
protein bindingMUL1;CCDC28B;SLC22A6;ADPRH;GJA1;SNX5;MAX;JAG1;PPARGC1A
protein kinase bindingCNPPD1;BCAR1;PTPRJ;CD226;MAP2K6;CDKN2A;GOLGA2;CCNL1A;DNM1
protein phosphatase 1 bindingPHACTR1;PPP1R11;TCTEX1D4;PHACTR3;PHACTR3B;PHACTR4;SH3RF2;LILRB1;PAWR
protein phosphatase type 1 activator activityPPP1R15A;PHACTR4;PHACTR4B
protein phosphatase type 1 regulator activityPPP1R15A;UBXN2A;PPP1R16A;PPP1R7;NSFL1C;PHACTR4B;UBXN2B;KCNS1;PHACTR3

PPP1R15A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R15A here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R15A.

CTBP2; PPP1R1A; Dlg4; microcystin-lr; MYC; POU3F3; BCAR1; PPP1CA; trpE; q81l21_bacan; secA2; q81w74_bacan; ZNF512B

Ohri, SS; Mullins, A; et al. Inhibition of GADD34, the Stress-Inducible Regulatory Subunit of the Endoplasmic Reticulum Stress Response, Does Not Enhance Functional Recovery after Spinal Cord Injury. PLOS ONE 9:-(2014).
Yong, KJ; Milenic, DE; et al. Impact of alpha-Targeted Radiation Therapy on Gene Expression in a Pre-Clinical Model for Disseminated Peritoneal Disease when Combined with Paclitaxel. PLOS ONE 9:-(2014).
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