PPP1R2
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Official Full Name
protein phosphatase 1, regulatory (inhibitor) subunit 2
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Overview
Protein phosphatase inhibitor 2 is an enzyme that in humans is encoded by the PPP1R2 gene. -
Synonyms
PPP1R2; protein phosphatase 1, regulatory (inhibitor) subunit 2; protein phosphatase inhibitor 2; IPP2; phosphatase inhibitor 2; phosphoprotein phosphatase; IPP-2; MGC87148;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | PPP1R2-29472TH | Recombinant Human PPP1R2 | Wheat Germ | N/A | 205 amino acids | |
Human | PPP1R2-2438H | Recombinant human PPP1R2, His-tagged | E.coli | His | ||
Human | PPP1R2-1908H | Recombinant Human PPP1R2, GST-tagged | E.coli | GST | 1-205AA | |
Human | PPP1R2-31217TH | Recombinant Human PPP1R2 | Wheat Germ | N/A | 100 amino acids | |
Human | PPP1R2-2937HCL | Recombinant Human PPP1R2 293 Cell Lysate | HEK293 | N/A | ||
Human | PPP1R2-391HF | Recombinant Full Length Human PPP1R2 Protein | In Vitro Cell Free System | 205 amino acids | ||
Human | PPP1R2-3291H | Recombinant Human PPP1R2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Mouse | PPP1R2-13231M | Recombinant Mouse PPP1R2 Protein | Mammalian Cell | His | ||
Mouse | PPP1R2-7016M-B | Recombinant Mouse PPP1R2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Ppp1r2-5071M | Recombinant Mouse Ppp1r2 Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | PPP1R2-7016M | Recombinant Mouse PPP1R2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | PPP1R2-4622R | Recombinant Rat PPP1R2 Protein | Mammalian Cell | His | ||
Rat | PPP1R2-4281R | Recombinant Rat PPP1R2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | PPP1R2-4281R-B | Recombinant Rat PPP1R2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | PPP1R2-3567R | Recombinant Rhesus monkey PPP1R2 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | PPP1R2-3385R | Recombinant Rhesus Macaque PPP1R2 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | PPP1R2-3385R-B | Recombinant Rhesus Macaque PPP1R2 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | PPP1R2-11693Z | Recombinant Zebrafish PPP1R2 | Mammalian Cell | His | ||
Chicken | PPP1R2-2967C | Recombinant Chicken PPP1R2 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- PPP1R2 Related Articles
PPP1R2 involved in several pathways and played different roles in them. We selected most pathways PPP1R2 participated on our site, such as Androgen biosynthesis, Metabolism, Metabolism of lipids and lipoproteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Androgen biosynthesis | CGA;POMCB;PPP1R2;CYP17A1 |
Metabolism | MED9;SAT1B;ACOT11A;SACM1LA;MED15;MED22;SLC25A20;PDZD11;CHST14 |
Metabolism of lipids and lipoproteins | PMVK;CPT2;CYP2AD3;ANKRD1;FAM213B;CDS1;CYP8B2;CERS4A;CERS3B |
Metabolism of steroid hormones and vitamin D | CYP2R1;CYP24A1;GC;STARD5;PPP1R2;CYP27B1;AKR1B15;HSD17B11 |
Steroid hormone biosynthesis | HSD3B1;HSD11B1;HSD17B12B;HSD17B12A;HSD3B4;H2-KE6;UGT2B7;UGT1A7;UGT1AB |
PPP1R2 has several biochemical functions, for example, 3-oxo-5-alpha-steroid 4-dehydrogenase activity, oxidoreductase activity, acting on the CH-CH group of donors. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R2 itself. We selected most functions PPP1R2 had, and list some proteins which have the same functions with PPP1R2. You can find most of the proteins on our site.
Function | Related Protein |
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3-oxo-5-alpha-steroid 4-dehydrogenase activity | SRD5A2A;SRD5A2B;PPP1R2;SRD5A1;SRD5A2;SRD5A3 |
oxidoreductase activity, acting on the CH-CH group of donors | COX15;SRD5A3;TECR;SRD5A2B;TM7SF2;TECRL2B;DPYDB;LBR;GCDHB |
PPP1R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R2.
PPP1CC; GSK3B; PPP1CA; LMTK2; TINF2; MYC; PPP1CB; Ppp1r10; Cep72; PPP1CC
- Q&As
- Reviews
Q&As (6)
Ask a questionIt has a complex relationship with other proteins. For example, it interacts with PPP1, regulating its activity. In addition, PPP1R2 also interacts with other proteins and participates in a variety of biological processes.
Treatment strategies for PPP1R2 include inhibition of its expression, modulation of its activity, or the use of gene therapy. For example, some studies have shown that the use of small molecule inhibitors against PPP1R2 can inhibit its activity and thus treat some PPP1R2-related diseases. In addition, it is also possible to treat related diseases by regulating the expression level of PPP1R2.
Studies have shown that the expression level of PPP1R2 is associated with a variety of diseases. For example, in some tumors, the expression level of PPP1R2 is upregulated, which may promote the proliferation and metastasis of tumor cells. In some neurodegenerative diseases, PPP1R2 expression levels may be down-regulated, leading to dysregulation of intracellular phosphorylation balance, which in turn leads to neuronal death.
There are still some limitations in the current research on PPP1R2, such as the lack of in-depth research on its specific mechanism of action and function, and the incomplete understanding of its relationship with diseases. In addition, since PPP1R2 is a multifunctional protein, regulating it may also have some side effects.
PPP1R2 plays an important regulatory role in cells. It binds to PPP1 and regulates the phosphorylation level of intracellular proteins by inhibiting or activating the activity of PPP1. This regulatory effect has important implications for many biological processes such as cell cycle, gene expression, and signal transduction.
Recent studies have found that PPP1R2 is also involved in intracellular signaling processes. These processes have an important impact on cell growth, differentiation and migration, and also provide new ideas for the treatment of some PPP1R2-related diseases.
Customer Reviews (3)
Write a reviewStrong anti-pollution ability, safe to use.
PPP1R2 has a wide range of applications and can be applied to various types of experiments.
The quality of the products is stable, which greatly improves the efficiency of our scientific research.
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