rbbp6
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  • Official Full Name
  • retinoblastoma binding protein 6
  • Background
  • The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
  • Synonyms
  • RBBP6; retinoblastoma binding protein 6; E3 ubiquitin-protein ligase RBBP6; P2P R; PACT; proliferation potential related protein; SNAMA; protein P2P-R; RB-binding Q-protein 1; retinoblastoma-binding Q protein 1; proliferation potential-related protein; p5
Cat.#:RBBP6-2200HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RBBP6, GST-tagged
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Cat.#:RBBP6-23HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human RBBP6 protein, GST-tagged
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Cat.#:RBBP6-1160ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RBBP6
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Cat.#:RBBP6-7794ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RBBP6
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Cat.#:RBBP6-1480HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RBBP6 cell lysate
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Protein Function

RBBP6 has several biochemical functions, for example, ligase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBBP6 itself. We selected most functions RBBP6 had, and list some proteins which have the same functions with RBBP6. You can find most of the proteins on our site.
Function
Related Protein
Function ligase activity
Related Protein ARIH1; LIG4; PDZRN3; MARCH2; CMTM2A; RNF123; UBE2F; TRIM37; UBE3C; RNF115
Function poly(A) RNA binding
Related Protein PPIB; NCBP1; SLC16A3; SF3B4; TAF15; SRP19; DCD; UBFD1; POP7; CCT6A
Function protein binding
Related Protein MAP3K4; NUP35; RIMS2; HLA-DRB3; FOXP3; IKZF1; RIOK3; EFS; ARHGEF10; ACVR1L
Function ubiquitin protein ligase activity
Related Protein RNF217; FLJ11011L; UBE2U; SIAH1A; HUWE1; CDC34A; MARCH8; UBE2G1; MSL2A; UBR3
Function ubiquitin-protein transferase activity
Related Protein IRAK1; TRAF4B; TRIM36; UBE3A; BRAP; FBXW11; HECW1B; RNF146; TRIM13; MARCH5
Function zinc ion binding
Related Protein WBP7; TAF3; LHX3; NR6A1; MLL1; MMP16; TRIM55B; RC3H2; MMP17; RASGRP1

Interacting Protein

RBBP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBBP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBBP6.
SRSF7; TFCP2; POLR2D; KHDRBS3; PIAS1; ZFYVE9; HP; PLG; APOH; ASGR1; TPT1; GLUL; CAPZA2; VAV2; GRB2; UBE2I; SMN1; pgi