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RBBP6

  • Official Full Name

    retinoblastoma binding protein 6

  • Overview

    The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
  • Synonyms

    RBBP6; retinoblastoma binding protein 6; E3 ubiquitin-protein ligase RBBP6; P2P R; PACT; proliferation potential related protein; SNAMA; protein P2P-R; RB-binding Q-protein 1; retinoblastoma-binding Q protein 1; proliferation potential-related protein; p5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RBBP6-2200H Recombinant Human RBBP6, GST-tagged E.coli GST N-term-118aa
Human RBBP6-23H Recombinant Human RBBP6 protein, GST-tagged Wheat Germ GST 1 a.a. - 118 a.a.
Human RBBP6-1480HCL Recombinant Human RBBP6 cell lysate N/A
Zebrafish RBBP6-1160Z Recombinant Zebrafish RBBP6 Mammalian Cell His
Zebrafish RBBP6-7794Z Recombinant Zebrafish RBBP6 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RBBP6 involved in several pathways and played different roles in them. We selected most pathways RBBP6 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RBBP6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

RBBP6 has several biochemical functions, for example, ligase activity, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBBP6 itself. We selected most functions RBBP6 had, and list some proteins which have the same functions with RBBP6. You can find most of the proteins on our site.

Function Related Protein
ligase activityHECW1;MARCH10;RNF40;UBE3A;UBE2G1A;UBE2NB;RNF144AA;COP1;GLULC
poly(A) RNA bindingHSP90AA1;NOP14;HNRNPR;RPL32;IMMT;EIF4G2;CKAP4;TIAL1;TDRD9
protein bindingUNC13D;GP1BA;CUBN;CD58;PPP4R4;BAZ2A;YWHAH;SCMH1;FNBP4
ubiquitin protein ligase activityHECTD3;ZNRF2;C18orf25;CDC34B;FBXO30;RNF149;TMEM189;HECTD2;ITCHA
ubiquitin-protein transferase activityUBE2O;TRIM69;TNFAIP3;UBE2G1;TSPAN17;LNX2B;BIRC7;FBXO3;UHRF2
zinc ion bindingCPD;ZNF207;AKT1S1;ZDHHC21;ADAMTS3;GATA1A;POLR2L;NR6A1B;ADAMDEC1

RBBP6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBBP6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBBP6.

SRSF7; TFCP2; POLR2D; KHDRBS3; PIAS1; ZFYVE9; HP; PLG; APOH; ASGR1; TPT1; GLUL; CAPZA2; VAV2; GRB2; UBE2I; SMN1; pgi

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