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RBBP7

  • Official Full Name

    retinoblastoma binding protein 7

  • Overview

    This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
  • Synonyms

    RBBP7; retinoblastoma binding protein 7; RbAp46; histone-binding protein RBBP7; RBBP-7; retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; retinoblastoma-binding protein RbAp46; histone acetyltransferase type B subunit 2; nucleosome-remodeling factor subunit RBAP46; G1/S transition control protein-binding protein RbAp46;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RBBP7-29048TH Recombinant Human RBBP7 Wheat Germ N/A 425 amino acids
Human RBBP7-2489HCL Recombinant Human RBBP7 293 Cell Lysate HEK293 N/A
Human RBBP7-5864H Recombinant Human RBBP7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RBBP7-428HF Recombinant Full Length Human RBBP7 Protein In Vitro Cell Free System 425 amino acids
Human RBBP7-1863H Recombinant Human RBBP7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human RBBP7-1010H Recombinant Human RBBP7 Protein (1-425 aa), His-SUMO-tagged E.coli His/SUMO 1-425 aa
Human RBBP7-1890HFL Recombinant Full Length Human RBBP7 Protein, C-Flag-tagged Mammalian cells Flag
Human RBBP7-1863H-B Recombinant Human RBBP7 Protein Pre-coupled Magnetic Beads HEK293
Mouse RBBP7-13978M Recombinant Mouse RBBP7 Protein Mammalian Cell His
Mouse RBBP7-7459M Recombinant Mouse RBBP7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RBBP7-7459M-B Recombinant Mouse RBBP7 Protein Pre-coupled Magnetic Beads HEK293
Mouse Rbbp7-5402M Recombinant Mouse Rbbp7 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat RBBP7-4950R Recombinant Rat RBBP7 Protein Mammalian Cell His
Rat RBBP7-4609R Recombinant Rat RBBP7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RBBP7-4609R-B Recombinant Rat RBBP7 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey RBBP7-845C Recombinant Cynomolgus RBBP7 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey RBBP7-588C-B Recombinant Cynomolgus Monkey RBBP7 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey RBBP7-588C Recombinant Cynomolgus Monkey RBBP7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RBBP7-3804R Recombinant Rhesus monkey RBBP7 Protein, His-tagged Mammalian Cell His
Rhesus Macaque RBBP7-3621R Recombinant Rhesus Macaque RBBP7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RBBP7-3621R-B Recombinant Rhesus Macaque RBBP7 Protein Pre-coupled Magnetic Beads HEK293
Chicken RBBP7-6236C Recombinant Chicken RBBP7 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RBBP7 Related Articles
  • RBBP7 Related Research Area

RBBP7 involved in several pathways and played different roles in them. We selected most pathways RBBP7 participated on our site, such as Cell Cycle, Cellular Senescence, Cellular responses to stress, which may be useful for your reference. Also, other proteins which involved in the same pathway with RBBP7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleSYCP2;DPF1;YWHABL;TGFB3;MCM3L;CENPC1;BARD1;CDC14A;RBX1
Cellular SenescenceBMI1A;E2F2;KDM6B;HIST1H1A;Txn1;TXN;EED;IGFBP7;HTATIP
Cellular responses to stressDPF1;EHMT2;HSBP1A;DNAJB6;IGFBP7;BMI1B;ATG9B;TXN2;RING1
Chromatin modifying enzymesSAP18;PBRM1L;TADA2A;MBD3A;EPC1;JHDM1D;ZZZ3;KDM2B;KAT8
Chromatin organizationCHD4;MSL2A;PADI1;KDM6B;WDR77;KDM2A;EP400;VPS72;PHF2
Chromosome MaintenanceCENPL;CENPH;CENPO;PANE1;APITD1;NPM1;RUVBL2;OIP5;DNA2
Deposition of new CENPA-containing nucleosomes at the centromereCENPL;CENPC1;CENPW;HJURP;CENPO;NPM1;APITD1;OIP5;RBBP7
EGFR1 Signaling PathwayAPPL2;CRKL;RBB4L;PITPNA;ERRFI1;RALBA;WNK1;PTK6;RGS5B

RBBP7 has several biochemical functions, for example, RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBBP7 itself. We selected most functions RBBP7 had, and list some proteins which have the same functions with RBBP7. You can find most of the proteins on our site.

Function Related Protein
RNA bindingRBMY1B;FXR2;PUS10;PAPOLG;RBM8A;DAZ4;RBFOX1L;HSP90B1;PTBP1
protein bindingROCK2A;AUNIP;HBXIP;NCALD;NDUFS1;ALS2;TMEM119;SF3B2;DOCK10

RBBP7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBBP7 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBBP7.

HDAC1; DHX30; CDK2AP1; Mta2; NR2E3; HIST2H4B

Tetu, B; Popa, I; et al. Immunohistochemical analysis of possible chemoresistance markers identified by micro-arrays on serous ovarian carcinomas. MODERN PATHOLOGY 21:1002-1010(2008).
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