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RBFOX1

  • Official Full Name

    RNA binding protein, fox-1 homolog (C. elegans) 1

  • Overview

    Fox1, also commonly referred to as Ataxin-2-binding protein 1, is an RNA binding protein involved in the regulation of tissue-specific alternative splicing. This protein contains a highly conserved RRM (RNA recognition motif) and associates with 5'-UGCAUGU-3' elements. This protein has been demonstrated to regulate alternative splicing of tissue specific exons and differentially spliced exons during erythropoiesis. Its alternative name, Ataxin-2-binding protein, is a result of its association with the C terminus of ataxin 2 which may contribute to the pathology of the neurogenerative disease spinocerebellar ataxia type 2 (SCA2).
  • Synonyms

    RBFOX1; RNA binding protein, fox-1 homolog (C. elegans) 1; RNA binding protein fox-1 homolog 1; fox-1 homolog A; ataxin 2 binding protein 1; ataxin-2-binding protein 1; hexaribonucleotide binding protein 1; A2bp; A2bp1; fox-1; Hrnbp1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RBFOX1-9164HCL Recombinant Human A2BP1 293 Cell Lysate HEK293 N/A
Human RBFOX1-853H Recombinant Human RBFOX1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RBFOX1-657H Recombinant Human RBFOX1 Protein, His-tagged E.coli His
Mouse RBFOX1-13983M Recombinant Mouse RBFOX1 Protein Mammalian Cell His
Mouse Rbfox1-5406M Recombinant Mouse Rbfox1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse RBFOX1-7462M-B Recombinant Mouse RBFOX1 Protein Pre-coupled Magnetic Beads HEK293
Mouse RBFOX1-7462M Recombinant Mouse RBFOX1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Rbfox1-7118R Recombinant Rat Rbfox1 protein, His & T7-tagged E.coli His/T7 Asp149~Ser399 (Accession # D3ZSL1)
Zebrafish RBFOX1-1437Z Recombinant Zebrafish RBFOX1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RBFOX1 Related Articles

RBFOX1 involved in several pathways and played different roles in them. We selected most pathways RBFOX1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RBFOX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

RBFOX1 has several biochemical functions, for example, RNA binding, mRNA binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBFOX1 itself. We selected most functions RBFOX1 had, and list some proteins which have the same functions with RBFOX1. You can find most of the proteins on our site.

Function Related Protein
RNA bindingRPS3;IFIT5;NUFIP2;U2AF1L4;TUT1;ENDOU;PRAC;ZNF385B;MRPL3
mRNA bindingRPL13A;KHSRP;KIAA0020;FXR1;RPS13;PARK7;RPS26;RBFOX1;RBMY1A1
nucleotide bindingEK1;ATP1A1A.1;RAB1;LMTK2;MYO5A;CTPS1A;BSK146;GRK1B;FYNB
protein C-terminus bindingMED12;NEFL;SIAH1A;XRCC6;AP2A1;ERCC3;FOXN3;KPNA3;CLIC6
protein bindingCAPN1;TRPC4AP;YAF2;CBFA2T3;ZNF69;CC2D2A;RHPN1;PRAM1;SDCBP

RBFOX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBFOX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBFOX1.

C1orf94; RBPMS; RBFOX2; ATXN1; ATN1; PSMF1; QKI; PLEKHA5; NUMBL

Utami, KH; Hillmer, AM; et al. Detection of Chromosomal Breakpoints in Patients with Developmental Delay and Speech Disorders. PLOS ONE 9:-(2014).
Ding, D; Lou, XY; et al. Recurrent Targeted Genes of Hepatitis B Virus in the Liver Cancer Genomes Identified by a Next-Generation Sequencing-Based Approach. PLOS GENETICS 8:-(2012).
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