rbm5
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  • Official Full Name
  • RNA binding motif protein 5
  • Background
  • This gene is a candidate tumor suppressor gene which encodes a nuclear RNA binding protein that is a component of the spliceosome A complex. The encoded protein plays a role in the induction of cell cycle arrest and apoptosis through pre-mRNA splicing of multiple target genes including the tumor suppressor protein p53. This gene is located within the tumor suppressor region 3p21.3, and may play a role in the inhibition of tumor transformation and progression of several malignancies including lung cancer.
  • Synonyms
  • RBM5; RNA binding motif protein 5; RNA-binding protein 5; H37; LUCA15; putative tumor suppressor LUCA15; renal carcinoma antigen NY-REN-9; G15; RMB5; FLJ39876
Cat.#:RBM5-2217HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RBM5, GST-tagged
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Cat.#:RBM5-31232THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RBM5, His-tagged
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Cat.#:RBM5-14014MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RBM5 Protein
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Cat.#:RBM5-4964RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RBM5 Protein
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Cat.#:RBM5-3822RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RBM5 Protein, His-tagged
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Cat.#:RBM5-2009CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RBM5
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Cat.#:RBM5-5879ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RBM5
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Cat.#:RBM5-2466HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RBM5 293 Cell Lysate
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Involved Pathway

RBM5 involved in several pathways and played different roles in them. We selected most pathways RBM5 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with RBM5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
PUS1; SMG9; CDK8; ZNF710; TDRD1; LAMTOR1; SAP30BP; SKI; EIF1AX; ELAVL1
Processing of Capped Intron-Containing Pre-mRNA
METTL3; WTAP; PTBP1; CLP1; THOC4; TTC6; PTBP1B; SUGP1; HNRNPL; CCAR1
mRNA Splicing
BCAS2; HNRPL; PRPF8; CD2BP2; TTC6; HNRNPH1; SF3A1; TXNL4A; HNRNPA0A; HNRNPL2
mRNA Splicing - Major Pathway
HNRNPA0A; TXNL4A; HNRNPD; PTBP1; HNRNPH1; YBX1; HNRNPA0L; HNRNPH1L; HNRNPA2B1; HNRNPR
mRNA processing
SNURF; Ankar; OASL2; DHX15; DDX39; LOC100862398; SF3B2; RBMS3; WBP4; CELF4

Protein Function

RBM5 has several biochemical functions, for example, DNA binding, RNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RBM5 itself. We selected most functions RBM5 had, and list some proteins which have the same functions with RBM5. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ASXL3; HIST1H4L; ZNF324; ANG3; ENG1A; ZFP28; PLAGL1; KDM5B; TDP2B; HIST1H2BJ
Function RNA binding
Related Protein PRAC; FUS; EIF2S2; RPL21; SF1; SNRPF; FAU; DDX3Y; RPL3; IFIT1
Function mRNA binding
Related Protein FMR1; SRRM4; IGF2BP2A; SNRNP70; FXR2; ZFP36; DHFR; RBFOX3; NUDT16; XPO5
Function nucleotide binding
Related Protein HINT1; PSMC1A; CKMB; SNRNP70; SLKA; ARL3L1; IFT22; RBM14B; RBM4; MCM6L
Function poly(A) RNA binding
Related Protein TMEM38A; SRSF1; AKAP8L; HMGB3; MRPS5; ZCCHC7; HSPE1; CPSF4; TPR; RBM12B2
Function protein binding
Related Protein TRIM21; ANKS1A; NDFIP1; POGZ; TXN; FGFRL1B; RANBP6; DDX42; TTK; VSIG4
Function zinc ion binding
Related Protein TIMM13; ADAM25; BAZ2B; MLL5; PCGF5A; PGGT1B; PHF21A; USP44; MARCH9; ZCCHC16

Interacting Protein

RBM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RBM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of RBM5.
DHX15; PRPF19