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RDH5

  • Official Full Name

    retinol dehydrogenase 5 (11-cis/9-cis)

  • Overview

    This gene encodes an enzyme belonging to the short-chain dehydrogenases/reductases (SDR) family. This retinol dehydrogenase functions to catalyze the final step in the biosynthesis of 11-cis retinaldehyde, which is the universal chromophore of visual pigments. Mutations in this gene cause autosomal recessive fundus albipunctatus, a rare form of night blindness that is characterized by a delay in the regeneration of cone and rod photopigments. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S1 (biogenesis of lysosomal organelles complex-1, subunit 1) gene.
  • Synonyms

    RDH5; retinol dehydrogenase 5 (11-cis/9-cis); RDH1, retinol dehydrogenase 5 (11 cis and 9 cis); 11-cis retinol dehydrogenase; HSD17B9; SDR9C5; short chain dehydrogenase/reductase family 9C; member 5; 11 cis RDH; 11 cis retinol dehydrogenase; 9 cis retinol specific dehydrogenase; FLJ39337; FLJ97089; RDH 5; RDH1; Retinol dehydrogenase 1; Retinol dehydrogenase 5 (11 cis/9 cis); Retinol dehydrogenase 5; Short chain dehydrogenase/reductase family 9C member 5; 11-cis RDH; OTTHUMP00000242975; OTTHUMP00000242976; OTTHUMP00000242988; 9-cis-retinol specific dehydrogenase; retinol dehydrogenase 5 (11-cis and 9-cis); short chain dehydrogenase/reductase family 9C, member 5;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RDH5-2240H Recombinant Human RDH5, GST-tagged E.coli GST 19-290aa
Human RDH5-2435HCL Recombinant Human RDH5 293 Cell Lysate HEK293 N/A
Zebrafish RDH5-3231Z Recombinant Zebrafish RDH5 Mammalian Cell His
Chicken RDH5-6278C Recombinant Chicken RDH5 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RDH5 involved in several pathways and played different roles in them. We selected most pathways RDH5 participated on our site, such as Retinol metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with RDH5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Retinol metabolismUGT1A9;CYP26B1;CYP3A41A;ALDH1A1;UGT1A2;UGT1A7;ALDH1A2;RETSAT;CYP3A25

RDH5 has several biochemical functions, for example, retinol dehydrogenase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RDH5 itself. We selected most functions RDH5 had, and list some proteins which have the same functions with RDH5. You can find most of the proteins on our site.

Function Related Protein
retinol dehydrogenase activityRDH11;SDR9C7;AKR1C3;RDH12;RDH1;HSD17B6;RDH10;DHRS9;RDH7

RDH5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RDH5 here. Most of them are supplied by our site. Hope this information will be useful for your research of RDH5.

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