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REG1A

  • Official Full Name

    regenerating islet-derived 1 alpha

  • Overview

    This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
  • Synonyms

    REG1A; regenerating islet-derived 1 alpha; REG, regenerating islet derived 1 alpha (pancreatic stone protein, pancreatic thread protein); lithostathine-1-alpha; pancreatic stone protein; pancreatic thread protein; PSP; PSPS; PSPS1; PTP; ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 alpha; Lithostathine 1 alpha precursor; MGC12447; P19; Pancreatic stone protein secretory; Protein X; REG; Regenerating islet derived 1 alpha; Regenerating islet derived 1 alpha pancreatic stone protein pancreatic thread protein; Regenerating protein I alpha; protein-X; REG-1-alpha; OTTHUMP00000160485; pancreatic stone protein, secretory; regene;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Cynomolgus Monkey
  • Human
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • hFc
  • His (Fc)
  • Avi
  • His|T7
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human REG1A-2336H Recombinant Human REG1A protein, His-tagged HEK293 His Met1-Asn166
Human REG1A-192H Recombinant Human Regenerating Islet-derived 1 Alpha, His-tagged E.coli His
Human REG1A-3707H Recombinant Human REG1A, His-tagged E.coli His
Human REG1A-2497HCL Recombinant Human REG1A cell lysate Human Cell N/A
Human REG1A-807H Recombinant Human REG1A Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human REG1A-2336HB Recombinant Human REG1A protein, His-tagged, Biotinylated HEK293 His
Human REG1A-6163H Recombinant Human REG1A Protein (Gln23-Asn166), C-His tagged Mammalian cells C-His Gln23-Asn166
Rat Reg1a-8766R Recombinant Rat Reg1a protein, hFc-tagged HEK293 hFc Met1-Asn100
Rat Reg1a-1758R Recombinant Rat Reg1a protein, His & T7-tagged E.coli His/T7 Gln22~Ala165 (Accession # P10758)
Rat REG1A-4987R Recombinant Rat REG1A Protein Mammalian Cell His
Rat REG1A-1364RCL Recombinant Rat REG1A cell lysate Human Cell N/A
Rat REG1A-4646R Recombinant Rat REG1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat REG1A-4646R-B Recombinant Rat REG1A Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus REG1A-89C Recombinant Cynomolgus REG1A protein(Met1-Asn166), His-tagged HEK293 C-His Met1-Asn166
Cynomolgus REG1A-88C Recombinant Cynomolgus REG1A protein, hFc-tagged HEK293 hFc Met1-Asn166
Cynomolgus Monkey REG1A-988CCL Recombinant Cynomolgus REG1A cell lysate Human Cell N/A
Rhesus Macaque REG1A-3844R Recombinant Rhesus monkey REG1A Protein, His-tagged Mammalian Cell His
Rhesus Macaque REG1A-3661R Recombinant Rhesus Macaque REG1A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque REG1A-3661R-B Recombinant Rhesus Macaque REG1A Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • REG1A Related Research Area

REG1A involved in several pathways and played different roles in them. We selected most pathways REG1A participated on our site, such as Insulin Signaling, Type II interferon signaling (IFNG), which may be useful for your reference. Also, other proteins which involved in the same pathway with REG1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Insulin SignalingARHGAP33;INPP4AA;MAP4K5;REG1A;MAP3K10;STXBP3A;MAP4K1;STXBP3;GRB14
Type II interferon signaling (IFNG)Ifna;IFI6;IFIT2;GBP1;REG1A

REG1A has several biochemical functions, for example, carbohydrate binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by REG1A itself. We selected most functions REG1A had, and list some proteins which have the same functions with REG1A. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingCD55;LGALS13;GALNTL4;GRIFIN;SIGLEC12;CD209B;LGALS9L1;Il2;ATRN
growth factor activityGMFB;CSF1A;IL4;FGF1A;OGN;FGF6A;BMP6;GDNFA;FGF12B

REG1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with REG1A here. Most of them are supplied by our site. Hope this information will be useful for your research of REG1A.

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