reg1a
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  • Official Full Name
  • regenerating islet-derived 1 alpha
  • Background
  • This gene is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV, based on the primary structures of the encoded proteins. This gene encodes a protein that is secreted by the exocrine pancreas. It is associated with islet cell regeneration and diabetogenesis and may be involved in pancreatic lithogenesis. Reg family members REG1B, REGL, PAP and this gene are tandemly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
  • Synonyms
  • REG1A; regenerating islet-derived 1 alpha; REG, regenerating islet derived 1 alpha (pancreatic stone protein, pancreatic thread protein); lithostathine-1-alpha; pancreatic stone protein; pancreatic thread protein; PSP; PSPS; PSPS1; PTP; ICRF; Islet cells regeneration factor; Islet of Langerhans regenerating protein; Lithostathine 1 alpha; Lithostathine 1 alpha precursor; MGC12447; P19; Pancreatic stone protein secretory; Protein X; REG; Regenerating islet derived 1 alpha; Regenerating islet derived 1 alpha pancreatic stone protein pancreatic thread protein; Regenerating protein I alpha; protein-X; REG-1-alpha; OTTHUMP00000160485; pancreatic stone protein, secretory; regene
Cat.#:REG1A-807HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human REG1A Protein, MYC/DDK-tagged
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Cat.#:REG1A-192HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Regenerating Islet-derived 1 Alpha, His-tagged
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Cat.#:REG1A-2336HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human REG1A, His tagged
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Cat.#:REG1A-3707HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human REG1A, His-tagged
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Cat.#:Reg1a-1758RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Reg1a protein, His & T7-tagged
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Cat.#:REG1A-4987RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat REG1A Protein
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Cat.#:Reg1a-8766RTag:Fc
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Reg1a, Fc tagged
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Cat.#:REG1A-88CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus REG1A, Fc tagged
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Cat.#:REG1A-89CTag:His
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus REG1A, His tagged
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Cat.#:REG1A-3844RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey REG1A Protein, His-tagged
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Cat.#:REG1A-2497HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human REG1A cell lysate
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Cat.#:REG1A-1364RCLTag:
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat REG1A cell lysate
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Cat.#:REG1A-988CCLTag:
Source (Host):HEK293Species:Cynomolgus Monkey
Product nameRecombinant Cynomolgus REG1A cell lysate
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Involved Pathway

REG1A involved in several pathways and played different roles in them. We selected most pathways REG1A participated on our site, such as Insulin Signaling, Type II interferon signaling (IFNG), which may be useful for your reference. Also, other proteins which involved in the same pathway with REG1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Insulin Signaling
MYO1C; GSK3AB; GRB14; MAPK6; MAP4K1; MAP3K2; MAPK4; RHOJ; MINK1; STXBP1A
Type II interferon signaling (IFNG)
IFIT2; REG1A; Ifna; IFI6; GBP1

Protein Function

REG1A has several biochemical functions, for example, carbohydrate binding, growth factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by REG1A itself. We selected most functions REG1A had, and list some proteins which have the same functions with REG1A. You can find most of the proteins on our site.
Function
Related Protein
Function carbohydrate binding
Related Protein SIGLEC6; CD34; ASGR1; CALR; CNTN2; LY75; PRPS1; KLRB1; CLEC5A; FBXO2
Function growth factor activity
Related Protein PRL2C3; ENDOU; GDF10; GPR19; LFT1; FGF18B; GDNFA; MANF; NDR2; GMFG