RHOB
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Official Full Name
ras homolog family member B
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Overview
Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze t -
Synonyms
RHOB; ras homolog family member B; ARH6, ARHB, ras homolog gene family, member B; rho-related GTP-binding protein RhoB; MST081; oncogene RHO H6; RHOH6; h6; rho cDNA clone 6; Aplysia RAS-related homolog 6; ras homolog gene family, member B; ARH6; AR;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- RHOB Related Articles
- RHOB Related Research Area
- RHOB Related Signal Pathway
RHOB involved in several pathways and played different roles in them. We selected most pathways RHOB participated on our site, such as Androgen receptor signaling pathway, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Androgen receptor signaling pathway | RANBP9;SVILA;CARM1;EGFR;SMAD3B;RHOB;PNRC1;KAT7B;DSTN |
| Axon guidance | ACTR2;RASGEF1A;EZRA;FGF10B;UNC5A;L1CAM;MYL9;EPHB6;TRIO |
| Developmental Biology | EFNB2A;WDR83;DUSP10;TRPC4;MED25;DPYSL3;SPRED3;INSM1B;CLTB |
| Focal Adhesion | SHC3;SOS1;TNC;MAPK1;VAV1;PDPK1B;SHC4;TNK1;TNW |
| G alpha (12/13) signalling events | ECT2;TIAM2;DCLRE1B;AKAP13;NET1;ARHGAP4;ABR;ARHGEF1A;MCF2L |
| GPCR downstream signaling | ADORA2B;PYYA;OPN1MW;RGS10;OXTRL;ABR;OR52B4;UTS2D;PROKR2 |
| GPVI-mediated activation cascade | CLEC1B;G6b;PIK3R6;FCER1GL;RHOGA;C6orf25;RHOB;PDPN;LCP2A |
| Hemostasis | EHD1;ATP2B3A;MAFGB;SERPINF2B;KIF15;OSTN;CEACAM6;ITGB3A;GNA13B |
RHOB has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOB itself. We selected most functions RHOB had, and list some proteins which have the same functions with RHOB. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| GDP binding | RALB;PRPS2;RAB4A;EIF2B1;SRP54B;RAB5C;RAB7A;RAB17;PCK1 |
| GTP binding | EEF1A1;DRG1;ARL4C;RAB5B;GNAIA;SEPT7;RASL11A;RHOV;GNA14 |
| GTPase activity | TUBA4A;GNAT1;ADSSL1;RAB38;TUBB2;RRAGD;RAB3AA;TUBB4B;RHOD |
| protein binding | ARRB1;SPRY4;MYLK2;REL;UNC13A;VHLL;USF2;ASPSCR1;RD3 |
RHOB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOB here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOB.
SMURF1; TNFAIP1; DIAPH1; DAAM1; Fnta; PHGDH; EIF1B; PRAF2; NQO2; NME2; DUT; FBN1; NEK2; ARHGDIA
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