rhob
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  • Official Full Name
  • ras homolog family member B
  • Background
  • Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze t
  • Synonyms
  • RHOB; ras homolog family member B; ARH6, ARHB, ras homolog gene family, member B; rho-related GTP-binding protein RhoB; MST081; oncogene RHO H6; RHOH6; h6; rho cDNA clone 6; Aplysia RAS-related homolog 6; ras homolog gene family, member B; ARH6; AR
Cat.#:RHOB-2291HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB, GST-tagged
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Cat.#:RHOB-27380THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB, His-tagged
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Cat.#:RHOB-30284THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB
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Cat.#:RHOB-3529HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ras Homolog Gene Family, Member B, His-tagged
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Cat.#:RHOB-14168MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RHOB Protein
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Cat.#:RHOB-5036RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RHOB Protein
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Cat.#:RHOB-858CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus RHOB Protein, His-tagged
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Cat.#:RHOB-3885RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RHOB Protein, His-tagged
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Cat.#:RHOB-6471CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RHOB
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Cat.#:RHOB-2356HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RHOB 293 Cell Lysate
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Involved Pathway

RHOB involved in several pathways and played different roles in them. We selected most pathways RHOB participated on our site, such as Androgen receptor signaling pathway, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Androgen receptor signaling pathway
CDKN1A; CREBBP; SVILA; NR2C2; CTNNB2; PIAS3; EFCAB6; KDM1A; AES; KAT5
Axon guidance
SEMA4D; SCN4A; RASGRP1; ARPC1B; GSK3B; PTPRA; PLXNC1; GDNF; JAK1; RAC2
Developmental Biology
MED18; DUSP7; NADL1.1; MYOD1; ITGB3A; KIF4A; PSPN; CAP2; PEBP1; TCF3B
Focal Adhesion
PDPK1; IGF1RB; PXN; ITGB1A; CAV3; ITGB7; PIK3R5; PPP1R12B; COL4A6; VEGFAA
G alpha (12/13) signalling events
ARHGEF1A; ARHGAP4; ARHGEF16; ECT2; ARHGAP4A; FGD4; KALRN; RHOB; TIAM2; ABR
GPCR downstream signaling
ADRB3; RLN3A; EDNRAB; RGS14; NMS; ADORA1; AMCF-II; PENKB; HRH3; LPAR2B
GPVI-mediated activation cascade
RHOGA; PDPN; C6orf25; CLEC1B; G6b; PIK3R6; LCP2A; FCER1GL; RHOB
Hemostasis
KIF4A; PIK3R6; S100A10A; MERTK; PDE10A; DOCK6; SLC3A2B; CXADR; CABLES1; BSG

Protein Function

RHOB has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOB itself. We selected most functions RHOB had, and list some proteins which have the same functions with RHOB. You can find most of the proteins on our site.
Function
Related Protein
Function GDP binding
Related Protein RALB; RAB8A; RAB7; RAP1B; RAB28; RHOA; RAB7L1; GEM; MIEF1; SEPT12
Function GTP binding
Related Protein EEFSEC; DNM3; RAB26; DNAJC27; RRAGD; RSG1; ARFIP2; ARL5C; RAB14; MRAS
Function GTPase activity
Related Protein GNB3; DNAJC27; TUBB2B; TUBA3D; TUBD1; GPN1; RAB42B; RAB40AL; RAB3D; IRGE4
Function protein binding
Related Protein ZNF365; CCL7; Kitl; MTOR; PDCD2; PPP4R2; DUSP21; IGF2BP3; ORAI2; DTNA

Interacting Protein

RHOB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOB here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOB.
SMURF1; TNFAIP1; DIAPH1; DAAM1; Fnta; PHGDH; EIF1B; PRAF2; NQO2; NME2; DUT; FBN1; NEK2; ARHGDIA

RHOB Related Articles

Chinestra, P; Olichon, A; et al. Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation. PLOS ONE 9:-(2014).
Tiburcio, MGS; Pinheiro, NM; et al. GTPases Rho distribution in intraepithelial and invasive neoplasias of the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 35:284-288(2014).