rhob
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  • Official Full Name
  • ras homolog family member B
  • Background
  • Rho family small GTPases, including Rho, Rac and cdc42, act as molecular switches, regulating processes such as cell migration, adhesion, proliferation and differentiation. They are activated by guanine nucleotide exchange factors (GEFs), which catalyze t
  • Synonyms
  • RHOB; ras homolog family member B; ARH6, ARHB, ras homolog gene family, member B; rho-related GTP-binding protein RhoB; MST081; oncogene RHO H6; RHOH6; h6; rho cDNA clone 6; Aplysia RAS-related homolog 6; ras homolog gene family, member B; ARH6; AR
Cat.#:RHOB-2291HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB, GST-tagged
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Cat.#:RHOB-27380THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB, His-tagged
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Cat.#:RHOB-30284THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RHOB
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Cat.#:RHOB-3529HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ras Homolog Gene Family, Member B, His-tagged
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Cat.#:RHOB-14168MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RHOB Protein
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Cat.#:RHOB-5036RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RHOB Protein
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Cat.#:RHOB-858CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus RHOB Protein, His-tagged
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Cat.#:RHOB-3885RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RHOB Protein, His-tagged
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Cat.#:RHOB-6471CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RHOB
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Cat.#:RHOB-2356HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RHOB 293 Cell Lysate
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Involved Pathway

RHOB involved in several pathways and played different roles in them. We selected most pathways RHOB participated on our site, such as Androgen receptor signaling pathway, Axon guidance, Developmental Biology, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Androgen receptor signaling pathway
RANBP9; PARK7; CMTM2A; RNF4; PIAS3; HMGB2A; TGFB1I1; GNB2L1; EGFR; CTNNB1
Axon guidance
CNTN1; ABL1; FGF8B; NRG4; L1CAM; ITGB3A; CSF2RA; DNM1; DPYSL3; EPHB3A
Developmental Biology
FGF10B; HIF3A; MED15; RASGEF1A; MYL9; DCC; SEMA4D; CNKSR1; SCN2B; AP2A1
Focal Adhesion
PARVAA; COL1A1; FLNB; BADB; PAK1; PIK3R5; CAPN2; PTK6; CDC42L; VEGFA
G alpha (12/13) signalling events
GNA13B; ADRA1B; RHOGA; TRIO; ABR; FGD4; OBSCN; KALRNB; ARHGAP4; FGD4A
GPCR downstream signaling
S1PR1; UTS2D; RGS10; PROKR1A; ADRA2A; OPN4; RGS7; RHOB; ECT2; AGTR2
GPVI-mediated activation cascade
PIK3R6; PDPN; RHOB; LCP2A; RHOGA; C6orf25; FCER1GL; G6b; CLEC1B
Hemostasis
F3B; MYB; APOA1B; ATP2B1B; KIF3B; IRF2; FCER1GL; DOCK7; DOCK10; STXBP3A

Protein Function

RHOB has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOB itself. We selected most functions RHOB had, and list some proteins which have the same functions with RHOB. You can find most of the proteins on our site.
Function
Related Protein
Function GDP binding
Related Protein RAB7L1; PIGC; RAB9B; RAB7; RAB35; ARL2; RAB31; RAB2A; RAB8B; RAB4A
Function GTP binding
Related Protein EEF2; RAB20; TRIM23; OLA1; PCK1; IRGQ; LGALS6; C9orf86; RAB18A; EHD2B
Function GTPase activity
Related Protein DNM1B; RRAGC; RAB34A; DIRAS1; GSPT2; CDC42; EEF2; RAB39BB; RAB9A; GNAL
Function protein binding
Related Protein ARHGEF12; TRAF7; USP9X; HECTD3; GOLPH3; Akap3; RYK; MINOS1; NSG1; ARMCX5

Interacting Protein

RHOB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOB here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOB.
SMURF1; TNFAIP1; DIAPH1; DAAM1; Fnta; PHGDH; EIF1B; PRAF2; NQO2; NME2; DUT; FBN1; NEK2; ARHGDIA

RHOB Related Articles

Chinestra, P; Olichon, A; et al. Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation. PLOS ONE 9:-(2014).
Tiburcio, MGS; Pinheiro, NM; et al. GTPases Rho distribution in intraepithelial and invasive neoplasias of the uterine cervix. EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY 35:284-288(2014).