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RHOQ

Official Full Name

ras homolog gene family, member Q
Overview

This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The encoded protein is an important signalling protein for sarcomere assembly and has been shown to play a significant role in the exocytosis of the solute carrier family 2, facilitated glucose transporter member 4 and other proteins, possibly acting as the signal that turns on the membrane fusion machinery. Three related pseudogene have been identified on chromosomes 2 and 14.
Synonyms

RHOQ; ras homolog gene family, member Q; ARHQ, RAS like, family 7, member A , RASL7A; rho-related GTP-binding protein RhoQ; TC10; ARHQ; Ras homolog gene family member Q; RAS like family 7 member A; Ras like protein family member 7A; Ras like protein TC10; Ras related GTP binding protein TC10; Ras-like protein family member 7A; Ras-like protein TC10; RASL7A; Rho related GTP binding protein RhoQ; RHOQ_HUMAN; TC10A; RAS-like, family 7, member A;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
His|GST
N/A
N
GST

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RHOQ-566H	Recombinant Human ras homolog family member Q, His-tagged	E.coli	His		Inquiry
Human	RHOQ-1192H	Recombinant Human RHOQ protein, His & GST-tagged	E.coli	His/GST	Met1~Cys202 (Accession # P17081)	Inquiry
Human	RHOQ-2296H	Recombinant Human RHOQ, His-tagged	E.coli	His	1-205aa	$319 / 25ug
Human	RHOQ-2347HCL	Recombinant Human RHOQ 293 Cell Lysate	HEK293	N/A		Inquiry
Human	RHOQ-5774H	Recombinant Human RHOQ Protein (Met1-Cys202), N-GST tagged	E.coli	N-GST	Met1-Cys202	Inquiry
Rat	RHOQ-5037R	Recombinant Rat RHOQ Protein	Mammalian Cell	His		Inquiry
Rat	RHOQ-4696R	Recombinant Rat RHOQ Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	RHOQ-4696R-B	Recombinant Rat RHOQ Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	RHOQ-10198Z	Recombinant Zebrafish RHOQ	Mammalian Cell	His		Inquiry
Chicken	RHOQ-6031C	Recombinant Chicken RHOQ	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
RHOQ Related Signal Pathway

RHOQ involved in several pathways and played different roles in them. We selected most pathways RHOQ participated on our site, such as Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Insulin signaling pathway	PRKAA1;PPP1CAB;PHKA2;RAPGEF1;CBLB;MAPK8B;PPP1CAA;MKNK1;PTPRF

RHOQ has several biochemical functions, for example, GBD domain binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOQ itself. We selected most functions RHOQ had, and list some proteins which have the same functions with RHOQ. You can find most of the proteins on our site.

Function	Related Protein
GBD domain binding
GTP binding	RAB33B;RHOC;GIMAP6;GNAO1B;RAB42;DNM1L;RRAGB;GUF1;RAB33A
GTPase activity	TUBA1C;RAB2A;ARHGDIB;RAB27B;DNM2A;RHOT1B;RALBB;RAB34;GEM
profilin binding	RHOQ;CTTN;DIAPH1;EVL;FMNL1;DIAP1;CYFIP1;VASP;HTT

RHOQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOQ here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOQ.

WAS; PAK1; CDC42BPA; CDC42BPG