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RLBP1

  • Official Full Name

    retinaldehyde binding protein 1

  • Overview

    The protein encoded by this gene is a 36-kD water-soluble protein which carries 11-cis-retinaldehyde or 11-cis-retinal as physiologic ligands. It may be a functional component of the visual cycle. Mutations of this gene have been associated with severe rod-cone dystrophy, Bothnia dystrophy (nonsyndromic autosomal recessive retinitis pigmentosa) and retinitis punctata albescens. [provided by RefSeq, Jul 2008]
  • Synonyms

    RLBP1; retinaldehyde binding protein 1; CRALBP; retinaldehyde-binding protein 1; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Chicken
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • His
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RLBP1-26519TH Recombinant Human RLBP1 Wheat Germ N/A 317 amino acids
Human RLBP1-425H Recombinant Human retinaldehyde binding protein 1, His-tagged E.coli His
Human RLBP1-5026H Recombinant Human RLBP1, His-tagged E.coli His
Human RLBP1-2315H Recombinant Human RLBP1, His-tagged E.coli His 1-317aa
Human RLBP1-18H Recombinant Human RLBP1, MYC/DDK-tagged HEK293 Myc/DDK
Human RLBP1-2328HCL Recombinant Human RLBP1 293 Cell Lysate HEK293 N/A
Human RLBP1-436HF Recombinant Full Length Human RLBP1 Protein In Vitro Cell Free System 317 amino acids
Human RLBP1-6612HFL Recombinant Full Length Human RLBP1, Flag-tagged Mamanlian cells Flag
Human RLBP1-3129H Recombinant Human RLBP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Rlbp1-5528M Recombinant Mouse Rlbp1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Chicken RLBP1-2194C Recombinant Chicken RLBP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RLBP1 Related Articles

RLBP1 involved in several pathways and played different roles in them. We selected most pathways RLBP1 participated on our site, such as Disease, Diseases associated with visual transduction, Diseases of signal transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with RLBP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
DiseaseKPNA4;TLR6;AP2S1;MYO18A;SFTPC;KPNA3;TAF1L;TCEA1;RDBP
Diseases associated with visual transductionRBP1;OPN1SW;RLBP1;STRA6;OPN1LW;OPN1MW;OPN1MW2;RBP4;TTR
Diseases of signal transductionOS9;STRA6;HEYL;KREMEN2;HDAC5;KREMEN1;OPN1MW2;CDC37;FGFR1OP
Retinoid cycle disease eventsRBP4;STRA6;RLBP1;RBP1
Signal TransductionAATF;CDC42EP1B;OXGR1A.1;LRIG1;KLHL12;EVC2;RGS7;TAAR1;ABR
The canonical retinoid cycle in rods (twilight vision)RBP4;RPE65A;RDH10;IRBP;ABCA4A;DHRS9;RPE65B;RDH12;MYO7A
The retinoid cycle in cones (daylight vision)OPN1LW1;RLBP1A;OPN1SW1;DHRS3A;DHRS3;OPN1LW2;RLBP1B;IRBP;RLBP1
Visual phototransductionMETAP2;RLN1;LRP10;BCO2L;RPE65B;RPE65A;SDR9C7;CNGA1;DHRS3A

RLBP1 has several biochemical functions, for example, 11-cis retinal binding, retinol binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RLBP1 itself. We selected most functions RLBP1 had, and list some proteins which have the same functions with RLBP1. You can find most of the proteins on our site.

Function Related Protein
11-cis retinal bindingOPN5;RLBP1;OPN4
retinol bindingCRABP2;C8G;CRABP1;RBP3;RBP1;RBP7;RBP2;ADH4;RBP5
transporter activityFABP12;SLC4A1B;CDH17;VPS9D1;SLC2A11L;AP1S2;RLBP1;FABP9;AP3D1

RLBP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RLBP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RLBP1.

Powner, MB; Gillies, MC; et al. Perifoveal Muller Cell Depletion in a Case of Macular Telangiectasia Type 2. OPHTHALMOLOGY 117:2407-2416(2010).
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