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RNPC3

Official Full Name

RNA-binding region (RNP1, RRM) containing 3
Overview

Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Synonyms

RNPC3; RNA-binding region (RNP1, RRM) containing 3; RNA-binding protein 40; FLJ20008; KIAA1839; RBM40; U11/U12 snRNP 65K; AI447568; MGC188204; RNA binding protein 40; 2810441O16Rik; C030014B17Rik; FLJ25070; KIAA183; RNA binding motif protein 40; RNA binding region (RNP1 RRM) containing 3; RNA binding region containing protein 3; RNP; U11/U12 65K; U11/U12 small nuclear ribonucleoprotein 65 KDa protein; U11/U12 snRNP 65 KDa protein; U11/U12-65K; RNA recognition protein; RNA-binding motif protein 40; RNA-binding region-containing protein 3;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	RNPC3-2261HCL	Recombinant Human RNPC3 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	RNPC3-14362M	Recombinant Mouse RNPC3 Protein	Mammalian Cell	His	Inquiry
Mouse	RNPC3-7698M	Recombinant Mouse RNPC3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	RNPC3-7698M-B	Recombinant Mouse RNPC3 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	RNPC3-3686Z	Recombinant Zebrafish RNPC3	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

RNPC3 involved in several pathways and played different roles in them. We selected most pathways RNPC3 participated on our site, such as Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, mRNA Splicing, which may be useful for your reference. Also, other proteins which involved in the same pathway with RNPC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	DNMT3B;MED13B;CSTF1;CLP1;ZNF205;CCNT2A;ZNF556;TBX5A;SKIB
Processing of Capped Intron-Containing Pre-mRNA	NXF1;HNRNPR;HNRNPA2B1;HNRNPH1L;THOC4;CLP1;CD2BP2;HNRNPA0;SNRNP35
mRNA Splicing	PTBP1;HNRNPH1;HNRNPD;HNRNPF;SF3A3;HNRNPH1L;CD2BP2;SFRS3A;HNRNPR
mRNA Splicing - Minor Pathway	ZMAT5;SF3B4;ZCRB1;YBX1;PDCD7;PRPF8;SNRNP48;SNRNP25;SNRNP35

RNPC3 has several biochemical functions, for example, U12 snRNA binding, nucleotide binding, pre-mRNA intronic binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RNPC3 itself. We selected most functions RNPC3 had, and list some proteins which have the same functions with RNPC3. You can find most of the proteins on our site.

Function	Related Protein
U12 snRNA binding	RNPC3;RBM41
nucleotide binding	NLRP9B;CLCN3;DAZ4;PFKMA;HDGF;CELF3A;RAP1AA;UCKL1A;EWSR1B
pre-mRNA intronic binding	RNPC3;RBM4;EP300;SOX9;RBM41;PRPF8;HNRNPA2B1

RNPC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RNPC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RNPC3.

PRNP; pepB; SMAD2; Srp72; PTBP3