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RORB

  • Official Full Name

    RAR-related orphan receptor B

  • Overview

    The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The specific functions of this protein are not known, but it has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation.
  • Synonyms

    RORB; RAR-related orphan receptor B; nuclear receptor ROR-beta; NR1F2; ROR BETA; RZRB; bA133M9.1; Nuclear receptor RZR beta; Nuclear receptor RZR-beta; Nuclear receptor subfamily 1 group F member 2; OTTHUMP00000021486; RAR related orphan receptor B; RAR related orphan receptor beta; Retinoic acid binding receptor beta; Retinoid-related orphan receptor-beta; RORB_HUMAN; RZR BETA; RAR-related orphan receptor beta; retinoic acid-binding receptor beta; retinoid-related orphan receptor beta; nuclear receptor subfamily 1 group F me; ROR-BETA; RZR-BETA;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RORB-30957TH Recombinant Human RORB Wheat Germ N/A 459 amino acids
Human RORB-2359H Recombinant Human RORB, GST-tagged E.coli GST 106-459aa
Human RORB-2360H Recombinant Human RORB protein, MYC/DDK-tagged HEK293 Myc/DDK
Human RORB-2246HCL Recombinant Human RORB 293 Cell Lysate HEK293 N/A
Human RORB-438HF Recombinant Full Length Human RORB Protein In Vitro Cell Free System 459 amino acids
Human RORB-6489H Recombinant Human RORB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RORB-2163HFL Recombinant Full Length Human RORB protein, Flag-tagged Mamanlian cells Flag
Mouse RORB-14380M Recombinant Mouse RORB Protein Mammalian Cell His
Mouse RORB-7707M Recombinant Mouse RORB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Rorb-5575M Recombinant Mouse Rorb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse RORB-7707M-B Recombinant Mouse RORB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RORB-3956R Recombinant Rhesus monkey RORB Protein, His-tagged Mammalian Cell His
Rhesus Macaque RORB-3773R Recombinant Rhesus Macaque RORB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RORB-3773R-B Recombinant Rhesus Macaque RORB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish RORB-5248Z Recombinant Zebrafish RORB Mammalian Cell His
Chicken RORB-6650C Recombinant Chicken RORB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RORB involved in several pathways and played different roles in them. We selected most pathways RORB participated on our site, such as Circadian rhythm, which may be useful for your reference. Also, other proteins which involved in the same pathway with RORB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Circadian rhythmPER3;ARNTL;PRKAA2;PRKAB1;PER1;CSNK1E;CUL1;PRKAA1;NPAS2

RORB has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, protein binding, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RORB itself. We selected most functions RORB had, and list some proteins which have the same functions with RORB. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingPPARG;Ar;STAT3;NR4A1;HNF4A;NR1I2;NR5A5;RORB;PPARA
protein bindingGAN;LRCH4;RNF220;ERAP1;FBXW5;NGFRB;KPNB1;KEAP1;BMPR1A
sequence-specific DNA bindingPPARAA;PHOX2BB;HOXB9;CREB3L3A;SIX4;NR4A1;EDF1;PNX;ARXA
steroid hormone receptor activityRORB;NR1I2;NR0B1;NR2E1;NR0B2;VDRB;PAQR8;RORAA;NR5A1B
transcription factor activity, sequence-specific DNA bindingBSX;STAT1A;Trl;ZFP629;PRDM1A;TSC22D1;NPAS1;MNX2B;ZKSCAN17
zinc ion bindingS100A5;DBF4B;TRIM43B;SEC24A;WBP4;PHF8;MICALL2;TRIM35-19;RARGA

RORB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RORB here. Most of them are supplied by our site. Hope this information will be useful for your research of RORB.

Clock; BHLHE40; RORC; CSNK2B

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