rpa1
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  • Official Full Name
  • replication protein A1, 70kDa
  • Background
  • RPA70 (HSSB, REPA1, RF-A, RP-A, p70) is a component of a heterotrimeric complex, composed of 70, 32/30 and 14 kDa subunits, collectively known as RPA. RPA is a single stranded DNA binding protein, whose DNA binding activity is believed to reside entirely
  • Synonyms
  • RPA1; replication protein A1, 70kDa; replication protein A1 (70kD); replication protein A 70 kDa DNA-binding subunit; HSSB; REPA1; RF A; RP A; RPA70; MSTP075; RP-A p70; RF-A protein 1; replication factor A protein 1; single-stranded DNA-binding protein; R
Cat.#:RPA1-2366HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPA1, GST-tagged
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Cat.#:RPA1-31145THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPA1, His-tagged
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Cat.#:RPA1-31146HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human RPA1, MYC/DDK-tagged
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Cat.#:RPA1-31147HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPA1, GST-tagged
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Cat.#:RPA1-1369CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RPA1
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Cat.#:RPA1-10194ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RPA1
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Cat.#:RPA1-2243HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RPA1 293 Cell Lysate
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Involved Pathway

RPA1 involved in several pathways and played different roles in them. We selected most pathways RPA1 participated on our site, such as DNA replication, Nucleotide excision repair, Mismatch repair, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPA1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
DNA replication
RNASEH2C; MCM6L; GMNN; RPA1; DBF4; POLA1; POLA2; RFC3; POLD1; LIG1
Nucleotide excision repair
ERCC4; COPS2; GTF2H1; RBX1; RPA1; PCNA; ZFP830; MCRS1; XPA; YY1
Mismatch repair
MSH2; POLD1; POLD4; RPA2; MSH3; SSBP1; PCNA; EXO1; MLH3; MSH6
Homologous recombination
EME1; RAD51B; RPA4; RAD54B; BRCA2; RPA1; FUZ; RAD54L; POLD2; BLM
Fanconi anemia pathway
FUZ; REV3L; RPA1; POLH; POLN; BRCA2; RPA2; RPA4; BRIP1; EME1

Protein Function

RPA1 has several biochemical functions, for example, G-protein coupled receptor activity, photoreceptor activity, receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPA1 itself. We selected most functions RPA1 had, and list some proteins which have the same functions with RPA1. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled receptor activity
Related Protein OLFCG1; OLFCS2; VMN1R49; TACR1A; MRGPRA8; MRGPRA7; MC5RA; GPR173; TACR3A; OR4D6
Function photoreceptor activity
Related Protein OPN3; PARAPINOPSINB; OPN4B; GRK7A; OPN4A; RHO; CRY4; VALOPA; TMTOPS2A; OPN5
Function receptor activity
Related Protein GRIA4A; ADIPOR2; TNFRSF10A; TNFRSF25; NLGN2A; KIR2DL1; TREML2; Siglece; ITGB1B; LILRB3

Interacting Protein

RPA1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPA1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPA1.
RPA2; RPA3; WRN

RPA1 Related Articles

Takaya, J; Kusunoki, S; et al. Protein interaction and cellular localization of human CDC45. JOURNAL OF BIOCHEMISTRY 153:381-388(2013).
Shen, GP; Pan, QH; et al. Human genetic variants of homologous recombination repair genes first found to be associated with Epstein-Barr virus antibody titers in healthy Cantonese. INTERNATIONAL JOURNAL OF CANCER 129:1459-1466(2011).