rpia
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  • Official Full Name
  • ribose 5-phosphate isomerase A
  • Background
  • The protein encoded by this gene is an enzyme, which catalyzes the reversible conversion between ribose-5-phosphate and ribulose-5-phosphate in the pentose-phosphate pathway. This gene is highly conserved in most organisms. The enzyme plays an essential role in the carbohydrate metabolism. Mutations in this gene cause ribose 5-phosphate isomerase deficiency. A pseudogene is found on chromosome 18.
  • Synonyms
  • RPIA; ribose 5-phosphate isomerase A; ribose-5-phosphate isomerase; ribose 5 phosphate epimerase; EC 5.3.1.6; MGC103524; Phosphoriboisomerase; Ribose 5 phosphate isomerase; ribose 5-phosphate epimerase; RPI; RPIA_HUMAN; zgc:103524
Cat.#:RPIA-1571HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Ribose 5-Phosphate Isomerase A, His-tagged
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Cat.#:RPIA-2373HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPIA, His-tagged
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Cat.#:RPIA-31147THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPIA, His-tagged
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Cat.#:RPIA-31148THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPIA, His-tagged
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Cat.#:RPIA-14402MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RPIA Protein
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Cat.#:RPIA-3968RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RPIA Protein, His-tagged
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Cat.#:RPIA-2838CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RPIA
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Cat.#:RPIA-1684ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RPIA
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Cat.#:RPIA-2231HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RPIA 293 Cell Lysate
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Involved Pathway

RPIA involved in several pathways and played different roles in them. We selected most pathways RPIA participated on our site, such as Pentose phosphate pathway, Metabolic pathways, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPIA were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pentose phosphate pathway
PRPS2; FBP2; GPIA; PGM1; PFKP; PGM2; FBP1B; TALDO1; PFKMB; PGLS
Metabolic pathways
DGUOK; PAFAH1B1; DNMT1; ITPKB; UGT1A4; CYP2A4; AGK; NADK2; UGT1A6A; UQCRC2
Carbon metabolism
TKTB; SDHC; DLST; HK3; MDH1; FBP1; PKMA; SHMT2; SUCLG2; PC
Biosynthesis of amino acids
PFKMB; IDH2; GLULC; ALDOAB; IDH3A; ENO3; GM5506; OTC; RPIA; ENO1

Protein Function

RPIA has several biochemical functions, for example, monosaccharide binding, protein binding, ribose-5-phosphate isomerase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPIA itself. We selected most functions RPIA had, and list some proteins which have the same functions with RPIA. You can find most of the proteins on our site.
Function
Related Protein
Function monosaccharide binding
Related Protein GPI1; RPIA; PGLS; TALDO1; UPK1A; GPI; GPR19; Siglece; FBP1
Function protein binding
Related Protein ALOX5AP; MEAF6; ADRM1; ZC3H15; ADCK3; C1orf35; APAF1; MZF1; LRRC20; THAP10
Function ribose-5-phosphate isomerase activity
Related Protein RPIA

Interacting Protein

RPIA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPIA here. Most of them are supplied by our site. Hope this information will be useful for your research of RPIA.
STK16; PTPN11; WDYHV1; GORASP2; PCMT1; CENPP

RPIA Related Articles

Kaur, PK; Dinesh, N; et al. Identification and characterization of a novel Ribose 5-phosphate isomerase B from Leishmania donovani. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 421:51-56(2012).