rps6ka6
Share
  • Official Full Name
  • ribosomal protein S6 kinase, 90kDa, polypeptide 6
  • Background
  • This gene encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways. [provided by RefSeq, Jan 2010]
  • Synonyms
  • RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; RSK4; PP90RSK4; ribosomal protein S6 kinase alpha-6; RSK-4; p90RSK6; p90-RSK 6; S6K-alpha 6; S6K-alpha-6; ribosomal S6 kinase 4; 90 kDa ribosomal protein S6 kinase 6;
Cat.#:RPS6KA6-427HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human RPS6KA6, GST-tagged, Active
+Inquiry
Cat.#:RPS6KA6-2436HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RPS6KA6, His-tagged
+Inquiry
Cat.#:RPS6KA6-30418THTag:
Source (Host):Species:Human
Product nameRecombinant Human RPS6KA6
+Inquiry
Cat.#:RPS6KA6-3329HTag:GST
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human RPS6KA6, GST tagged
+Inquiry
Cat.#:RPS6KA6-674HCLTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human RPS6KA6 cell lysate
+Inquiry

Involved Pathway

RPS6KA6 involved in several pathways and played different roles in them. We selected most pathways RPS6KA6 participated on our site, such as MAPK signaling pathway, Oocyte meiosis, mTOR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPS6KA6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
Pdgfa&Pdgfb; NGF; LRRK2; FGF13B; AKT2L; RAP1AA; MAPK11; TRP53; MOS; MAPKAPK5
Oocyte meiosis
CDC23; ITPR3; PTTG1; ANAPC5; CPEB3; PRKACB; PPP2R5EA; ANAPC1; PPP2CA; PPP3R1B
mTOR signaling pathway
EIF4E1B; INS1; EIF4E1C; PRKAA2; TSC1; PIK3CG; RICTOR; HIF1AB; EIF4EA; CAB39L
Long-term potentiation
ITPR3; CAMK4; MAPK3; MAPK1; PPP3CA; RAF1; MAP2K2; GRIN2D; PRKACA; PPP1CB
Neurotrophin signaling pathway
MAP2K7; BRAF; CAMK2A; CAMK2G; BAD; ARHGDIG; CALML5; TRP53; RPS6KA2; SH2B3
Progesterone-mediated oocyte maturation
CCNA1; BUB1; CPEB1B; GNAI2B; RAF1; ANAPC5; ANAPC11; SPDYB; PPP1R2P9; HSP90AA1.2
Insulin resistance
PCK1; AKT3A; PPARGC1A; PIK3CB; PIK3CD; SLC2A2; TNFRSF1A; NR1H2; GFPT1; MTOR

Protein Function

RPS6KA6 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RPS6KA6 itself. We selected most functions RPS6KA6 had, and list some proteins which have the same functions with RPS6KA6. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ATAD2; NDUFA13; NEK12; IRAK3; TTLL4; CDK8; MAP3K6; MET; PFTK1; MARK2
Function magnesium ion binding
Related Protein ATP4A; RRAGC; RPS6KA3B; PKM; DXO; PKM2; TSSK4; ATP8B1; HPGDS; ITPK1
Function protein kinase activity
Related Protein CSF1RA; FYNB; MAPK8A; PHKG1B; PANK1A; STK17B; DAPK1; NEK1; CAMKK1A; CDK5
Function ribosomal protein S6 kinase activity
Related Protein RPS6KA3A; RPS6KA4; RPS6KA6; RPS6KA3; RPS6KA3B; RPS6KA2; RPS6KB1; RPS6KB2; RPS6KA1; RPS6KB1B

Interacting Protein

RPS6KA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPS6KA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPS6KA6.
HSP90AB1; DNAJC13; MED24; RPLP1; CLEC3B; CENPB; RXRA; NR4A1; DNMT1; MAPK3; MASP1; UFM1; LMO4; MPP1; CEBPZ; RBPJ; FZD5; DHX34; ADIRF; ZNF746