Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

RPTOR

  • Official Full Name

    regulatory associated protein of MTOR, complex 1

  • Overview

    This gene encodes a component of a signaling pathway that regulates cell growth in response to nutrient and insulin levels. The encoded protein forms a stoichiometric complex with the mTOR kinase, and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase. The protein positively regulates the downstream effector ribosomal protein S6 kinase, and negatively regulates the mTOR kinase. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    KOG1; Mip1; KIAA1303; regulatory-associated protein of mTOR; raptor; p150 target of rapamycin (TOR)-scaffold protein containing WD-repeats; RPTOR; regulatory associated protein of MTOR, complex 1;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RPTOR-30506TH Recombinant Human RPTOR Wheat Germ N/A 379 amino acids
Human RPTOR-1543HCL Recombinant Human RPTOR cell lysate N/A
Human RPTOR-2666H Recombinant Human RPTOR Protein, His-tagged E.coli N-His Asn1020-Arg1335
Human RPTOR-448HF Recombinant Full Length Human RPTOR Protein In Vitro Cell Free System 379 amino acids
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RPTOR Related Articles
  • RPTOR Related Research Area
  • RPTOR Related Signal Pathway

RPTOR involved in several pathways and played different roles in them. We selected most pathways RPTOR participated on our site, such as mTOR signaling pathway, PIK-Akt signaling pathway, AMPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPTOR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mTOR signaling pathwayMAPK1;IGF1;DDIT4;TSC1;TSC1B;PIK3CB;PDPK1B;RPS6KA3A;ULK3
PIK-Akt signaling pathwayITGB7;LPAR2;ITGA9;GNB4;GNGT1;PPP2R2D;ITGB6;PIK3R2;KITLG
AMPK signaling pathwayRPS6KB1;Scd2;SCD;IRS4;ELAVL1;LEPR;IGF1;EEF2;Scd1
Insulin signaling pathwayPYGMA;PIK3CG;RPS6KB1B;RAPGEF1;HRAS;PRKAG2A;EIF4E1B;SOCS3;SHC2
MicroRNAs in cancerCasp3;ITGA5;SIRT1;ABCB1A;HOXD10;CDCA5;CCND1;RPTOR;TNN

RPTOR has several biochemical functions, for example, 14-3-3 protein binding, RNA polymerase III type 1 promoter DNA binding, RNA polymerase III type 2 promoter DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPTOR itself. We selected most functions RPTOR had, and list some proteins which have the same functions with RPTOR. You can find most of the proteins on our site.

Function Related Protein
14-3-3 protein bindingPRKCZ;SRPK2;HDAC7;HDAC7A;AKT1;IRS2;PRKCE;DDIT4;AANAT
RNA polymerase III type 1 promoter DNA bindingMAF1;MTOR;RPTOR
RNA polymerase III type 2 promoter DNA bindingMAF1;RPTOR;MTOR
RNA polymerase III type 3 promoter DNA bindingMTOR;RPTOR;MAF1
TFIIIC-class transcription factor bindingMTOR;RPTOR
protein bindingRPLP0;FAM110A;TSG101;GTF2IRD2;WFIKKN1;HNRNPF;NF1;PRDM7;COL1A2
protein complex bindingLRP2;IGBP1;TUB;CRIPT;KCTD5;LCA5;STRN;UFD1L;PFKP
protein kinase bindingDLG1;AP1B1;NEK9;PPP1CB;GCSAM;CCND1;RPTOR;STX1B;TTN

RPTOR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPTOR here. Most of them are supplied by our site. Hope this information will be useful for your research of RPTOR.

MTOR

Szymanska, P; Martin, KR; et al. Computational Analysis of an Autophagy/Translation Switch Based on Mutual Inhibition of MTORC1 and ULK1. PLOS ONE 10:-(2015).
Rajkumar, AP; Christensen, JH; et al. Analysis of t(9;17)(q33.2; q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder. BIPOLAR DISORDERS 17:205-211(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All RPTOR Products

Required fields are marked with *

My Review for All RPTOR Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends