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RTN3

  • Official Full Name

    reticulon 3

  • Overview

    This gene belongs to the reticulon family of highly conserved genes that are preferentially expressed in neuroendocrine tissues. This family of proteins interact with, and modulate the activity of beta-amyloid converting enzyme 1 (BACE1), and the production of amyloid-beta. An increase in the expression of any reticulon protein substantially reduces the production of amyloid-beta, suggesting that reticulon proteins are negative modulators of BACE1 in cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    RTN3; reticulon 3; reticulon-3; ASY interacting protein; ASYIP; HAP; homolog of ASY protein; isoforme III; neuroendocrine specific protein like 2; NSP like protein II; NSPL2; NSPLII; RTN3 A1; Reticulon3; NSP-like protein 2; OTTHUMP00000237754; OTTHUMP00000237755; OTTHUMP00000237756; OTTHUMP00000237757; OTTHUMP00000237759; NSP-like protein II; neuroendocrine-specific protein-like 2; neuroendocrine-specific; RTN3-A1;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Rat
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • Zebrafish
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RTN3-2122HCL Recombinant Human RTN3 293 Cell Lysate HEK293 N/A
Rat RTN3-5194R Recombinant Rat RTN3 Protein Mammalian Cell His
Rat RTN3-4853R Recombinant Rat RTN3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RTN3-4853R-B Recombinant Rat RTN3 Protein Pre-coupled Magnetic Beads HEK293
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL7004XF Recombinant Full Length Xenopus Tropicalis Reticulon-3(Rtn3) Protein, His-Tagged E.coli expression system His Full Length (1-213)
Zebrafish RTN3-11298Z Recombinant Zebrafish RTN3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RTN3 involved in several pathways and played different roles in them. We selected most pathways RTN3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RTN3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

RTN3 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RTN3 itself. We selected most functions RTN3 had, and list some proteins which have the same functions with RTN3. You can find most of the proteins on our site.

Function Related Protein
protein bindingSIRT6;COMMD10;KIAA1217;HMGB4;TIFA;IKBKB;CNTF;PIM1;SIRT1

RTN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RTN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RTN3.

PTPN9; 346157; CDIPT; SNX1; PTPN9; PPP2R3C

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