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Rab27a

  • Official Full Name

    RAB27A, member RAS oncogene family

  • Overview

    The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified.
  • Synonyms

    RAB27A; RAB27A, member RAS oncogene family; ras-related protein Rab-27A; GS2; HsT18676; RAB27; RAM; rab-27; GTP-binding protein Ram; MGC117246;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E. coli
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RAB27A-2479H Recombinant Human RAB27A, His-tagged E.coli His
Human RAB27A-2613HCL Recombinant Human RAB27A 293 Cell Lysate HEK293 N/A
Human RAB27A-334H Recombinant Human RAB27A protein, GST-tagged E. coli GST 1-221 aa
Human RAB27A-592H Recombinant Human RAB27A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RAB27A-3364H Recombinant Human RAB27A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RAB27A-4119H Recombinant Human RAB27A Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Rab27a-658M Recombinant Mouse Rab27a Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Rab27a-1106R Active Recombinant Rat RAB27A, Member RAS Oncogene Family E.coli N/A
Rat Rab27a-1107R Active Recombinant Rat RAB27A, Member RAS Oncogene Family, GST-tagged E.coli GST
Rat Rab27a-714R Active Recombinant Rat Rab27a Protein E.coli N/A
Rat RAB27A-4882R Recombinant Rat RAB27A Protein Mammalian Cell His
Rat RAB27A-4541R-B Recombinant Rat RAB27A Protein Pre-coupled Magnetic Beads HEK293
Rat RAB27A-4541R Recombinant Rat RAB27A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RAB27A-3740R Recombinant Rhesus monkey RAB27A Protein, His-tagged Mammalian Cell His
Rhesus Macaque RAB27A-3557R-B Recombinant Rhesus Macaque RAB27A Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RAB27A-3557R Recombinant Rhesus Macaque RAB27A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish RAB27A-3338Z Recombinant Zebrafish RAB27A Mammalian Cell His
Chicken RAB27A-4044C Recombinant Chicken RAB27A Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Rab27a Related Articles
  • Rab27a Related Research Area

Rab27a involved in several pathways and played different roles in them. We selected most pathways Rab27a participated on our site, such as Deregulation of Rab and Rab Effector Genes in Bladder Cancer, Insulin processing, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with Rab27a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Deregulation of Rab and Rab Effector Genes in Bladder CancerSYTL3;SYTL2;EXPH5;MYRIP;MLPH;UNC13D;RAB27A;RPH3AL;TBC1D10A
Insulin processingPCSK1;EXOC6;EXOC5;CPE;PCSK2;EXOC3;RAB27A;SLC30A8;SLC30A6
Metabolism of proteinsGALNT5;THSD7A;CCT6A;PCSK2;CHCHD4;FBXW4;TOMM40;ADAMTS20;TIMM9
Peptide hormone metabolismSPCS3;SLC30A8;MBOAT4;EXOC8;GRP;GPR119;CGB5;GZMH;DPP4

Rab27a has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Rab27a itself. We selected most functions Rab27a had, and list some proteins which have the same functions with Rab27a. You can find most of the proteins on our site.

Function Related Protein
GDP bindingRAB9A;ARL3;RAB27B;SEPT12;RAB7;RRAS;RAB10;RAB18;RAP2C
GTP bindingTHG1L;RAB3DB;RAC3;ARL11;SEPT7B;RRAGD;RHOQ;RAB40B;MFHAS1
GTPase activityGSPT1L;TUBA4A;RAB18A;GIMAP7;MFN1B;RAB1B;RAB3B;TUFM;RAB35
myosin V bindingRAB3B;RAB8A;FUS;RAB3C;RAB39B;RAB27B;RAB11B;RAB3D;RAB25
protein bindingSLC3A1;GCH1;SLBP;RUVBL1;GEMIN7;OS9;RHOB;CRK;PEX14
protein domain specific bindingRCC2;NFASC;HIST2H4A;WNT1;IST1;ATP1A1;YWHABB;PICK1;NF2

Rab27a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Rab27a here. Most of them are supplied by our site. Hope this information will be useful for your research of Rab27a.

MLPH; ACTA1; GDF9; EEF1A1; ZBTB16; RBM48; RIF1; COPS6; cpsG; CEP126; C14orf1

Nagashima, S; Jirintai, S; et al. Hepatitis E virus egress depends on the exosomal pathway, with secretory exosomes derived from multivesicular bodies. JOURNAL OF GENERAL VIROLOGY 95:2166-2175(2014).
Bustos, MA; Lucchesi, O; et al. Rab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosis. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:E2057-E2066(2012).
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