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RCBTB2

Official Full Name

regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
Overview

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.
Synonyms

RCBTB2; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2; CHC1L, chromosome condensation 1 like; RCC1 and BTB domain-containing protein 2; CHC1 L; CHC1L; Chromosome condensation 1 like; RCBT2; RCC1 and BTB domain containing protein 2; RCC1 like G exchanging factor; RCC1 like G exchanging factor RLG; Regulator of chromosome condensation (RCC1) and BTB domain containing protein 2; Regulator of chromosome condensation and BTB domain containing protein 2; RLG; CHC1-L; RCC1-like G exchanging factor RLG; regulator of chromosome condensation and BTB domain-containing protein 2;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
His|T7
Myc
DDK
MYC
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RCBTB2-2446HCL	Recombinant Human RCBTB2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	RCBTB2-4005H	Recombinant Human RCBTB2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	RCBTB2-1936H	Recombinant Human RCBTB2 protein, His & T7-tagged	E.coli	His/T7	Ala394~Leu519 (Accession # O95199)	Inquiry
Mouse	Rcbtb2-283M	Recombinant Mouse Rcbtb2 Protein, MYC/DDK-tagged	HEK293T	MYC/DDK		Inquiry
Rat	RCBTB2-4974R	Recombinant Rat RCBTB2 Protein	Mammalian Cell	His		Inquiry
Rat	RCBTB2-4633R	Recombinant Rat RCBTB2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	RCBTB2-4633R-B	Recombinant Rat RCBTB2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry

Involved Pathway
Protein Function
Interacting Protein
RCBTB2 Related Articles

RCBTB2 involved in several pathways and played different roles in them. We selected most pathways RCBTB2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RCBTB2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RCBTB2 has several biochemical functions, for example, Ran guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RCBTB2 itself. We selected most functions RCBTB2 had, and list some proteins which have the same functions with RCBTB2. You can find most of the proteins on our site.

Function	Related Protein
Ran guanyl-nucleotide exchange factor activity	RANBP10;RCC1;RCBTB2;RANGRF;SERGEF;ALS2
protein binding	AAAS;ASAP2;DUSP12;SPRR2A;PPP1R3C;TSC1;GGACT;TTN;TCTEX1D1

RCBTB2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCBTB2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RCBTB2.

FARS2; UBE2I; HSP90AB1; NUDCD2; COPS4

Creytens, D; van Gorp, J; et al. Atypical spindle cell lipoma: a clinicopathologic, immunohistochemical, and molecular study emphasizing its relationship to classical spindle cell lipoma. VIRCHOWS ARCHIV 465:97-108(2014).

Kang, M; Cho, JW; et al. Fine localization of a new cataract locus, Kec, on mouse chromosome 14 and exclusion of candidate genes as the gene that causes cataract in the Kec mouse. BMB REPORTS 41:651-656(2008).

Armellini, A; Sarasquete, ME; et al. Low expression of ZHX2, but not RCBTB2 or RAN, is associated with poor outcome in multiple myeloma. BRITISH JOURNAL OF HAEMATOLOGY 141:212-215(2008).