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RFX2

Official Full Name

regulatory factor X, 2 (influences HLA class II expression)
Overview

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Synonyms

RFX2; regulatory factor X, 2 (influences HLA class II expression); DNA-binding protein RFX2; regulatory factor X 2; DNA binding protein RFX2; trans-acting regulatory factor 2; HLA class II regulatory factor RFX2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

C
Myc
DDK
GST
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	RFX2-2264H	Recombinant Human RFX2, GST-tagged	E.coli	GST	C-term-300aa	$319 / 25ug
Human	RFX2-2399HCL	Recombinant Human RFX2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	RFX2-369H	Recombinant Human RFX2 Protein, MYC/DDK-tagged, C13 and N15-labeled	HEK293	C-Myc/DDK		Inquiry
Mouse	RFX2-14113M	Recombinant Mouse RFX2 Protein	Mammalian Cell	His		Inquiry
Mouse	RFX2-7550M-B	Recombinant Mouse RFX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	RFX2-7550M	Recombinant Mouse RFX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Rfx2-5480M	Recombinant Mouse Rfx2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rat	RFX2-5008R	Recombinant Rat RFX2 Protein	Mammalian Cell	His		Inquiry
Rat	RFX2-4667R	Recombinant Rat RFX2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	RFX2-4667R-B	Recombinant Rat RFX2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	RFX2-2085Z	Recombinant Zebrafish RFX2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

RFX2 involved in several pathways and played different roles in them. We selected most pathways RFX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RFX2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX2 itself. We selected most functions RFX2 had, and list some proteins which have the same functions with RFX2. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZNF496;DMRT2;POLDIP2;ZBTB16A;NUSAP1;RORCB;ZFP641;VED;ZNF143
RNA polymerase II core promoter proximal region sequence-specific DNA binding	ZNF664;ELF1;ZNF92;CEBPE;MITFB;E2F8;HHEX;GCFC2;PITX3
transcription factor activity, sequence-specific DNA binding	HSF1;NFE2L1B;ZFP322A;AATF;CREBBP;STAT6;HOXB8A;SIX2;ZNF397

RFX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX2.

RFX6; MDFI