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Ric8

Official Full Name

resistance to inhibitors of cholinesterase 8 homolog (C. elegans)
Synonyms

RIC-8; Ric8a; AI114950;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	RIC8-14218M	Recombinant Mouse RIC8 Protein	Mammalian Cell	His	Inquiry
Mouse	RIC8-7600M-B	Recombinant Mouse RIC8 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Mouse	RIC8-7600M	Recombinant Mouse RIC8 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein
Ric8 Related Articles

Ric8 involved in several pathways and played different roles in them. We selected most pathways Ric8 participated on our site, such as cyclic AMP biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ric8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
cyclic AMP biosynthesis	ARHGAP33;DOCK8;RIC8;RALGAPA1;PDC;RAP1GAP2;GARNL3

Ric8 has several biochemical functions, for example, G-protein alpha-subunit binding, GTPase activator activity, guanyl-nucleotide exchange factor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ric8 itself. We selected most functions Ric8 had, and list some proteins which have the same functions with Ric8. You can find most of the proteins on our site.

Function	Related Protein
G-protein alpha-subunit binding	LPAR1;CRHR1;AGTR1A;LPAR3;F2RL1;NUCB1;IGF1R;PPP5C;F2R
GTPase activator activity	RABGAP1;RAP1GAP2A;ARHGAP19;ARAP2;TBC1D3B;STXBP5A;ARHGAP12;AGAP2;RIN3
guanyl-nucleotide exchange factor activity	RAPGEF6;ARHGEF1B;GCGR;RALGPS2;ARHGEF3L;GAPVD1;TRIOA;FGD4;RAPGEF1B
protein binding	KRTAP10-7;CALB1;WHRN;FARS2;SNAPC5;CC10;CHD2;SRM;IFT122

Ric8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ric8 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ric8.

Iqcb1

Gong, JJ; Grodsky, JD; et al. A Ric8/Synembryn Homolog Promotes Gpa1 and Gpa2 Activation To Respectively Regulate Cyclic AMP and Pheromone Signaling in Cryptococcus neoformans. EUKARYOTIC CELL 13:1290-1299(2014).

de Mendoza, A; Sebe-Pedros, A; et al. The Evolution of the GPCR Signaling System in Eukaryotes: Modularity, Conservation, and the Transition to Metazoan Multicellularity. GENOME BIOLOGY AND EVOLUTION 6:606-619(2014).