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Ryr2

  • Official Full Name

    ryanodine receptor 2, cardiac

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RYR2-358H Recombinant Human RYR2 Mammalian Cell His
Human RYR2-356H Recombinant Human RYR2 protein (Cardiac), His-tagged E.coli His Met1-Arg606
Human RYR2-4019H-B Recombinant Human RYR2 Protein Pre-coupled Magnetic Beads HEK293
Human RYR2-4019H Recombinant Human RYR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RYR2-14608M Recombinant Mouse RYR2 Protein Mammalian Cell His
Mouse RYR2-7862M Recombinant Mouse RYR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RYR2-7862M-B Recombinant Mouse RYR2 Protein Pre-coupled Magnetic Beads HEK293
Rat RYR2-5209R Recombinant Rat RYR2 Protein Mammalian Cell His
Rat RYR2-4868R Recombinant Rat RYR2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RYR2-4868R-B Recombinant Rat RYR2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Ryr2 Related Articles

Ryr2 involved in several pathways and played different roles in them. We selected most pathways Ryr2 participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Cardiac muscle contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ryr2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayPPIFB;ADRB3;PLCZ1;SPHK1;VDAC2;PTGER1A;CALML3;RYR3;GRM1
cAMP signaling pathwayRAC3;MAPK10;GPR119;MAPK8;GRIN1;DRD1A;MAPK1;ATP1A3;NPR1
Cardiac muscle contractionATP1B2B;MYL4;COX7A3;ATP1B1;CACNG7;UQCR11;UQCRC2A;COX7A2;COX5AA
Adrenergic signaling in cardiomyocytesATP1A2A;GNAI2B;GNAI1;CALM2A;Adcy4;CREB3L3A;CALM1;MAPK13;SCN4BA
Circadian entrainmentPER2;ADCYAP1R1;KCNJ6;GNB4;PLCB2;KCNJ3;CAMK2B;GNB1;GNAQ
Insulin secretionPLCB4;PRKACG;PRKACB;CAMK2B;KCNN4;GNA11;KCNJ11;PRKCG;KCNMB2
Oxytocin signaling pathwayCAMK1;ACTB;CALML3;CAMK2B;CALML5;PLCB2;PIK3CA;MYL9;NFATC2
Pancreatic secretionSCTR;RAB3D;PLCB1;PLA2G3;CELA3A;CELA2A;CLCA1;PRKCG;CTRL
Hypertrophic cardiomyopathy (HCM)PRKAB1;RYR2;TPM4;ITGA8;ACE;TNF;ITGA9;MYBPC3;PRKAB2
Arrhythmogenic right ventricular cardiomyopathy (ARVC)ACTN2;CACNG4;ITGB4;TCF7;CACNB1;CTNNA3;CACNG6;SGCA;ACTN3
Dilated cardiomyopathyGNAS;SGCB;DMD;DAG1;TNNC1;CACNG8;MYL3;ITGA3;MYBPC3

Ryr2 has several biochemical functions, for example, calcium channel activity, calcium ion binding, calcium-induced calcium release activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Ryr2 itself. We selected most functions Ryr2 had, and list some proteins which have the same functions with Ryr2. You can find most of the proteins on our site.

Function Related Protein
calcium channel activitySLC24A2;SLC24A4A;SLC24A1;TRPC5;AKR1C1;CACNG2A;TRPC4A;CACNA1DA;TRPV4
calcium ion bindingFKBP9;PCDH10A;GNPTAB;EPS15;S100A1;PLA2G2D;CASQ1A;PVALB4;CABP2
calcium-induced calcium release activityPKD2;RYR3;RYR2
calcium-release channel activityJPH3;RYR3;RASA3;JPH2;RYR2;TRPV1;RYR1
calmodulin bindingMYO5B;MYO1A;PLCB1;ADD1;CAMKK1;MAPKAPK2B;TRPM4;CNN3B;PHKA2
enzyme bindingAPOA5;SRC;HIST1H2AK;NPM2;HIST1H2AI;SUDS3;MTA1;TH;ATXN10
identical protein bindingGDF5;ENTPD2;CCDC155;DAAM1;CAV1;CLDN7;DYNLT1F;DYNLRB1;DRG1
intracellular ligand-gated calcium channel activityRYR2;TRPA1;ITPR3;ITPR1;AKR1C1
ion channel bindingKCNQ1;RIMS3;SNTA1;PDE4B;RANGRF;FKBP1B;SCN5A;CHERP;AKAP9
protein bindingCAV2;MEMO1;BLOC1S5;CCDC101;ERBB4;RGS2;WDR4;DNAAF2;BCL3
protein kinase A catalytic subunit bindingPRKAR1B;PKIA;RYR2;EZR;PRKAR2A;PJA2;CSK;GSK3B;KCNQ1
protein kinase A regulatory subunit bindingAKAP7;KCNQ1;ACBD3;AKAP6;RYR2;PRKACA;AKAP9;ARFGEF2;PJA2
protein self-associationMDH2;EPB49;ACHE;ABCD3;ZKSCAN17;TRIM32;NKX3-1;CTSB;TMEM190
ryanodine-sensitive calcium-release channel activityRYR2;RYR1;RYR3;RYR1B
suramin binding

Ryr2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ryr2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ryr2.

FKBP1B; MDM2; PRKACA; FKBP1A; vgrG7; q81z75_bacan; SMAD5; ALB; CFTR; AKAP6

Moore, CJ; Shao, CH; et al. Malondialdehyde and 4-hydroxynonenal adducts are not formed on cardiac ryanodine receptor (RyR2) and sarco(endo)plasmic reticulum Ca2+-ATPase (SERCA2) in diabetes. MOLECULAR AND CELLULAR BIOCHEMISTRY 376:121-135(2013).
Qiu, AW; Yang, Q; et al. Interleukin-6 prevents NMDA-induced neuronal death via Gp130 signaling-dependent IP3R inhibition. NEUROENDOCRINOLOGY LETTERS 34:529-538(2013).
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