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SC5DL

Official Full Name

sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
Overview

This gene encodes an enzyme of cholesterol biosynthesis. The encoded protein catalyzes the conversion of lathosterol into 7-dehydrocholesterol. Mutations in this gene have been associated with lathosterolosis. Alternatively spliced transcript variants encoding the same protein have been described.
Synonyms

SC5DL; sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like; sterol C5 desaturase (ERG3 delta 5 desaturase homolog, fungal) like , sterol C5 desaturase (fungal ERG3, delta 5 desaturase) like; lathosterol oxidase; S5DES; 3beta hydroxysteroid delta5 desaturase; C 5 sterol desaturase; Delta 5 desaturase like; Delta(7) sterol 5 desaturase; ERG3; Fungal ERG3; Lathosterol 5 desaturase; MGC93101; SC5D; Sterol C5 desaturase (ERG3 delta 5 desaturase homolog, S. cerevisiae) like; Sterol C5 desaturase; C-5 sterol desaturase; lathosterol 5-desaturase; lathosterol dehydrogenase; delta(7)-sterol 5-desaturase; fungal ERG3, delta-5-desaturase-like; 3beta-hydroxysteroid-delta5-desaturase;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	SC5DL-2051HCL	Recombinant Human SC5DL 293 Cell Lysate	HEK293	N/A	Inquiry
Rhesus Macaque	SC5DL-4084R	Recombinant Rhesus monkey SC5DL Protein, His-tagged	Mammalian Cell	His	Inquiry
Rhesus Macaque	SC5DL-3901R-B	Recombinant Rhesus Macaque SC5DL Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rhesus Macaque	SC5DL-3901R	Recombinant Rhesus Macaque SC5DL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry

Involved Pathway
Protein Function
Interacting Protein

SC5DL involved in several pathways and played different roles in them. We selected most pathways SC5DL participated on our site, such as Steroid biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with SC5DL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Steroid biosynthesis	SC4MOL;CELL;LIPA;DHCR7;CPN1;FAXDC2;MSMO1;Cel;CYP51
Metabolic pathways	ALAS2;CYP7A1;NMRK2;HIBADHB;CYP27B1;MGAT1;CAD;ATP6V0E2;PNP6

SC5DL has several biochemical functions, for example, C-5 sterol desaturase activity, iron ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SC5DL itself. We selected most functions SC5DL had, and list some proteins which have the same functions with SC5DL. You can find most of the proteins on our site.

Function	Related Protein
C-5 sterol desaturase activity	FADS1;SC5DL
iron ion binding	CYP2C54;CYP2D10;LCN2;CYP4A10;PLOD3;OGFOD1;HBAE1;CYP4Z1;CYP2C8

SC5DL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SC5DL here. Most of them are supplied by our site. Hope this information will be useful for your research of SC5DL.