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SRI

  • Official Full Name

    sorcin

  • Overview

    Sorcin, also known as SRI, is a 22-kDa calcium-binding protein initially identified in multidrug-resistant cells. SRI modulates excitation-contraction coupling in the heart and contributes to calcium homeostasis in the heart sarcoplasmic reticulum.
  • Synonyms

    SRI; sorcin; 22 kDa protein; Calcium binding protein amplified in mutlidrug resistant cells; CP 22; CP-22; CP22; SCN; Sorcin (class 4 gene); SORCN_HUMAN; V19; H_RG167B05.1; OTTHUMP00000161663; OTTHUMP00000205590; OTTHUMP00000206386; OTTHUMP00000213080; OTTHUMP00000225575; calcium binding protein amplified in mutlidrug-resistant cells;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Insect Cells
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • MYC
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SRI-8653H Recombinant Human SRI protein(Met1-Val198), His&GST-tagged Insect Cells N-His&GST Met1-Val198
Human SRI-492H Recombinant Human SRI, None tagged Insect Cell His
Human SRI-2953H Recombinant Human SRI, His-tagged E.coli His 1-198aa
Human SRI-3478H Recombinant Human SRI, His-tagged E.coli His
Human SRI-001HCL Recombinant Human SRI cell lysate Insect Cell N/A
Human SRI-1986H Recombinant Human SRI protein Insect Cells N/A Met1-Val198
Human SRI-1882H Recombinant Human SRI Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SRI-3527H Recombinant Human SRI protein, GST-tagged E.coli GST 1-198aa
Mouse SRI-15983M Recombinant Mouse SRI Protein Mammalian Cell His
Mouse SRI-8717M Recombinant Mouse SRI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse SRI-8717M-B Recombinant Mouse SRI Protein Pre-coupled Magnetic Beads HEK293
Mouse Sri-420M Recombinant Mouse Sri Protein, MYC/DDK-tagged HEK293T MYC/DDK
Cynomolgus Monkey SRI-975C Recombinant Cynomolgus SRI Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey SRI-718C Recombinant Cynomolgus Monkey SRI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey SRI-718C-B Recombinant Cynomolgus Monkey SRI Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SRI-4465R Recombinant Rhesus monkey SRI Protein, His-tagged Mammalian Cell His
Rhesus Macaque SRI-4281R Recombinant Rhesus Macaque SRI Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SRI-4281R-B Recombinant Rhesus Macaque SRI Protein Pre-coupled Magnetic Beads HEK293
Zebrafish SRI-10691Z Recombinant Zebrafish SRI Mammalian Cell His
Chicken SRI-3622C Recombinant Chicken SRI Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

SRI involved in several pathways and played different roles in them. We selected most pathways SRI participated on our site, such as Ion channel transport, Stimuli-sensing channels, Transmembrane transport of small molecules, which may be useful for your reference. Also, other proteins which involved in the same pathway with SRI were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ion channel transportAno3;TRPC5;FXYD6;TRPM6;ASIC1A;TTYH3;CLCN4-2;SCNN1D;GABRR2A
Stimuli-sensing channelsANO9;TRPM1;SLC17A3;CLCNK;ASIC1A;Ano3;TRPM4C;ANO6;CLCN4-2
Transmembrane transport of small moleculesCLCA1;SLC20A1B;SLC1A3A;ATP8B1;SLC5A6A;TRPA1B;GSDMA2;SLC35B3;SLC13A3

SRI has several biochemical functions, for example, calcium channel regulator activity, calcium ion binding, calcium-dependent cysteine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SRI itself. We selected most functions SRI had, and list some proteins which have the same functions with SRI. You can find most of the proteins on our site.

Function Related Protein
calcium channel regulator activitySGK2A;TSPAN13;CRISP1;PRKCB;CACNA2D2;GRM7;Crisp4;GRM6A;CACNB2
calcium ion bindingNKD2A;PCDHA4;EFHC2;ATP2C1;PCDH2G13;DSG2.1;PVALB6;LOC100686744;PGS1
calcium-dependent cysteine-type endopeptidase activityCAPN3A;CAPN12;CAPN2B;CAPNS1B;CAPN11;SOLH;CAPN1;CAPNS1A;CAPN13
identical protein bindingRUNX1T1;ALK;FUS;HOOK2;ZNF3;CST3;PHC2;YWHAZ;SIAH1A
ion channel bindingPHPT1;KCNQ3;KCNQ1;GPD1L;RIMS3;KCNIP2;RANGRF;FAM115C;FYN
protease bindingADAMTSL4;CNTNAP2;BCL2;DPP4;TP53;TIMP3;MBL1;UBC;FN1
protein bindingMETTL15;ZNHIT6;ADSS;MRPS23;MRPL15;AHNAK;LAMTOR3;CDCA7L;TUT1
protein heterodimerization activityHMG20B;CD3G;TPD52L1;SNX5;TCF4;H2AFX;HYPM;Fzd4;HIST1H2BF
receptor bindingKNG1;PTK2;FGF18B;CCL2;PLAT;CD58;SNX17;CADM2A;CX3CL1
repressing transcription factor bindingHDAC5;SRI;MYC;RELA;CTBP1;MAGEA2B;RUNX2;SKI;DDX20

SRI has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SRI here. Most of them are supplied by our site. Hope this information will be useful for your research of SRI.

CALCOCO2; PDE4C; TCF12; PRR13; PSEN2; VCAM1; STAT3

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