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SDS

  • Official Full Name

    serine dehydratase

  • Overview

    This gene encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
  • Synonyms

    SDS; serine dehydratase; L-serine dehydratase/L-threonine deaminase; SDH; L serine deaminase; TDH; L-serine deaminase; OTTHUMP00000241529; L-serine dehydratase; L-serine ammonia-lyase; L-threonine dehydratase;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SDS-2555H Recombinant Human SDS, His-tagged E.coli His 1-218aa
Human SDS-2004HCL Recombinant Human SDS 293 Cell Lysate HEK293 N/A
Human SDS-2621H Recombinant Human SDS Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Mouse Sds-5737M Recombinant Mouse Sds Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat SDS-5295R Recombinant Rat SDS Protein Mammalian Cell His
Rat SDS-4954R-B Recombinant Rat SDS Protein Pre-coupled Magnetic Beads HEK293
Rat SDS-4954R Recombinant Rat SDS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque SDS-4118R Recombinant Rhesus monkey SDS Protein, His-tagged Mammalian Cell His
Rhesus Macaque SDS-3935R-B Recombinant Rhesus Macaque SDS Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque SDS-3935R Recombinant Rhesus Macaque SDS Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SDS Related Articles

SDS involved in several pathways and played different roles in them. We selected most pathways SDS participated on our site, such as Biosynthesis of amino acids, Biosynthesis of antibiotics, Carbon metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with SDS were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Biosynthesis of amino acidsMAT2AL;GLUL;IDH3G;ENO1A;ARG2;ASS1;PYCRL;PFKL;RPIA
Biosynthesis of antibioticspykF;AK8;DLD;EHHADH;GLYCTK;CTH;ACAA2;CYP51A1;AGXT
Carbon metabolismPRPS1;ALDOAB;GOT2A;RPIA;TALDO1;HAO2;ENO1A;ALDOC;PDHA1B
Cysteine and methionine metabolismMPST;MAT1A;DNMT3AB;ADI1;BHMT;MDH2;MRI1;SDS;GOT2B
Glycine, serine and threonine metabolismCBS;ALAS1;GLDC;GRHPR;PSPH;SRR;GATM;GCSHA;SHMT1
L-serine degradationSDSL;SDS
L-threonine degradation VSDSL;SDS;DBT
Metabolic pathwaysDDOST;NT5C1B-RDH14;MGAT1B;ATP5O;PHGDH;AOC1;GALNT18A;POLD1;ABP1

SDS has several biochemical functions, for example, L-serine ammonia-lyase activity, L-threonine ammonia-lyase activity, protein homodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SDS itself. We selected most functions SDS had, and list some proteins which have the same functions with SDS. You can find most of the proteins on our site.

Function Related Protein
L-serine ammonia-lyase activitySRR;SDSL;SDS
L-threonine ammonia-lyase activitySDS;SDSL
protein homodimerization activitySTUB1;UNC13A;SHMT1;NBL1;CPNE1;NAMPT;TIMM10;CRYM;HLA-G
pyridoxal phosphate bindingSPTLC1;AGXT;CCBL2;MARC2;CBSB;ACCSL;SRR;SPTLC2;PYGL

SDS has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDS here. Most of them are supplied by our site. Hope this information will be useful for your research of SDS.

Song, YN; Li, ZX; et al. Effect of malondialdehyde treatment on the IgE binding capacity and conformational structure of shrimp tropomyosin. FOOD CHEMISTRY 175:374-380(2015).
Nipate, SS; Hurali, PB; et al. Evaluation of anti-inflammatory, anti-nociceptive, and anti-arthritic activities of Indian Apis dorsata bee venom in experimental animals: biochemical, histological, and radiological assessment. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY 37:171-184(2015).
  • Q&As
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