serping1
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  • Official Full Name
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
  • Background
  • This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
  • Synonyms
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; SERPING1; C1IN; C1NH; HAE1; HAE2; C1INH; C1 INH; C1 inhibitor; esterase inhibitor; Serine (or cysteine) proteinase inhibitor clade G member 1; OTTHUMP00000197004; Serpin G1; C1-inhibiting factor; C1-INH
Cat.#:Serping1-534RTag:His
Source (Host):HEK293Species:Rat
Product nameRecombinant Rat Serping1 Protein, His-tagged
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Cat.#:SERPING1-999HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SERPING1 Protein, MYC/DDK-tagged
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Cat.#:SERPING1-108HTag:
Source (Host):CHOSpecies:Human
Product nameRecombinant Human SERPING1 protein
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Cat.#:SERPING1-2344HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SERPING1, His tagged
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Cat.#:SERPING1-280HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SERPING1 Protein, His-tagged
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Cat.#:SERPING1-7570HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SERPING1, His-tagged
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Cat.#:SERPING1-924HTag:His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human SERPING1 Protein, His-tagged
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Cat.#:SERPING1-14963MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SERPING1 Protein
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Cat.#:Serping1-281MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Serping1 Protein, His-tagged
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Cat.#:Serping1-282MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Serping1 Protein, His-tagged
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Cat.#:Serping1-283MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Serping1 Protein, His-tagged
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Cat.#:Serping1-284MTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat TRIM21 Protein, His-tagged
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Cat.#:Serping1-285RTag:His
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Serping1 Protein, His-tagged
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Cat.#:SERPING1-5345RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SERPING1 Protein
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Cat.#:SERPING1-6673ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SERPING1
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Cat.#:SERPING1-73HTag:
Source (Host):Species:Human
Product nameNative Human C1 Esterase inhibitor
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Cat.#:SERPING1-97HTag:
Source (Host):Species:Human
Product nameNative Human C1 Esterase Inhibitor (C1-INH)
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Cat.#:SERPING1-2615HCLTag:
Source (Host):HEK293Species:Human
Product nameRecombinant Human SERPING1 cell lysate
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Cat.#:SERPING1-181HTag:
Source (Host):Species:Human
Product nameHuman C1 Inhibitor (Plasma) Reference standard
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Cat.#:SERPING1-27HTag:
Source (Host):Species:Human
Product nameHuman C1-Inhibitor Reference standard
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Involved Pathway

SERPING1 involved in several pathways and played different roles in them. We selected most pathways SERPING1 participated on our site, such as Complement and coagulation cascades, Pertussis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SERPING1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Complement and coagulation cascades
SERPINC1; C1QA; GM5077; PROC; C5AR1; THBD; PLAU; C8G; CR1L; PLAT
Pertussis
GNAI1; C4BPB; NFKB1; IL1A; RHOA; TRAF6; GNAI2; C1RA; CALM2; TICAM2

Protein Function

SERPING1 has several biochemical functions, for example, protein binding, serine-type endopeptidase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SERPING1 itself. We selected most functions SERPING1 had, and list some proteins which have the same functions with SERPING1. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein Pilrb1; LAIR1; AIP; NRIP2; SRGAP2; CLEC7A; ZNF177; TRPC5; NIP7; CDK16
Function serine-type endopeptidase inhibitor activity
Related Protein PAPLNB; SERPINA3; PI3; SERPINA3K; SERPINA6; RECK; PCSK1NL; SERPINA10; HRG; SERPINB12

Interacting Protein

SERPING1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SERPING1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SERPING1.
p27958-pro_0000037573; f_hcvh; NR4A1; BAG6; purL; smc3; ALB