Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

SFPI1

Official Full Name

SFFV proviral integration 1
Synonyms

SFPI1; SFFV proviral integration 1; transcription factor PU.1; 31 kDa Transforming Protein; 31 kDa-transforming protein; Hematopoietic transcription factor PU.1; OF; PU.1; SPI 1 proto oncogene; SPI A; Spi1; SPI1_HUMAN; Spleen focus forming virus (SFFV) proviral integration oncogene spi1; Spleen Focus Forming Virus Proviral Integration Oncogene; SFFV proviral integration 1 protein; Dis1; Dis-1; Spi-1; Sfpi-1; Tcfpu1; Tfpu.1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SFPI1-15006M	Recombinant Mouse SFPI1 Protein	Mammalian Cell	His	Inquiry
Mouse	SFPI1-8082M	Recombinant Mouse SFPI1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SFPI1-8082M-B	Recombinant Mouse SFPI1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SFPI1 involved in several pathways and played different roles in them. We selected most pathways SFPI1 participated on our site, such as Osteoclast differentiation, HTLV-I infection, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SFPI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Osteoclast differentiation	IFNG;TYK2;SOCS1;LILRA4;FOSB;GRB2;TGFBR2;TGFB2;FCGR3B
HTLV-I infection	CCND3;H2-AA;ITGB2;EGR1;WNT3;H2-AB1;ANAPC11;HRAS;ANAPC2
Epstein-Barr virus infection	TRAF2;HLA-DQB1;MAPK13;RAN;PSMC6;POLR2J2;HSPA6;SFPI1;SYK
Pathways in cancer	PGF;MLH1;PIAS2;NOS2;FADD;BAD;IL-8;MAPK9;WNT11
Transcriptional misregulation in cancer	TRP53;IL2RB;FUS;HIST1H3F;H3F3A;MEF2C;LRP2BP;RUNX2;PAX3
Acute myeloid leukemia	GRB2;RARA;RPS6KB1;CEBPA;IKBKG;LEF1;RAF1;PIK3R3;FLT3

SFPI1 has several biochemical functions, for example, DNA binding, NFAT protein binding, RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SFPI1 itself. We selected most functions SFPI1 had, and list some proteins which have the same functions with SFPI1. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ORC6L;CHD4A;MYPOP;HER4.2;LBX1;ZFP146;IRF3;ZNF526;POLR2J3
NFAT protein binding	GATA4;FOXP3;PPARA;SFPI1;SPI1;MAPK14
RNA binding	Akap17b;IFIT5;FXR1;APOBEC3G;IGF2BP3;HNRNPAB;AKAP1B;CRNKL1;HNRNPM
RNA polymerase II core promoter proximal region sequence-specific DNA binding	HHEX;NKX3-2;ATF3;NFATC2;KLF5;TCF3A;MAFB;ELF4;HOXA7
RNA polymerase II core promoter sequence-specific DNA binding	TFAP2A;H2AFY;SP1;IRF7;TBR1;SFPI1;RREB1;TRP53;SP3
RNA polymerase II distal enhancer sequence-specific DNA binding	ARX;POU4F1;NR1H4;GZF1;SPI1;NFKB1;SFPQ;FLI1;NR2F6
RNA polymerase II transcription factor binding	GATA4;GATA1;TRPS1;KDM1A;GATA2B;WWP2;MEF2A;GATA5;Ar
core promoter binding	IFI203;HDAC1;PSPC1;FOXP3;E2F2;MTA1;DHX36;NPAS2;MYBBP1A
protein binding	CSK;INCENP;PPIG;NCKIPSD;TIMM50;PPP1R2P9;C4BPB;NRP1B;RPS25
sequence-specific DNA binding	NR4A2A;HOXB6;ZSCAN4;Trl;CDX1B;CUX2;HOXA9B;MAFF;HOXC4
transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	ATF3;FOSL2;CREB3;JDP2;RBPJB;SNAI3;FOSL1A;BATF2;FOS
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	PAX3;ATF1;SFPI1;HNF4A;AHR;USF1;FOXP3;GTF2IRD1;T
transcription factor activity, sequence-specific DNA binding	EOMES;DMRT2;POU4F3;EFCAB11;ZNF668;ZFP551;MNX1;SIM1B;CSDA
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	NR2E1;EBF4;NKX2;ZFP292;MYB;MYC;TLX1;FOSL1;SOX2
transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	MEOX2;TARDBP;ZEB2;NFE2L1;FUBP1;NFATC1;PROP1;ARID3B;FOXH1
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	NFATC2;KLF16;GATA3;ZKSCAN3;NFIL3-4;EN1;GZF1;CREBBP;MYPOP

SFPI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SFPI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SFPI1.

Nono; Cd1d1; Hoxa10; Gfi1; GFI1; id3_mouse_gene; ari3a_mouse_gene; cd1d1_mouse_gene; vpre2_mouse_gene; Smad3