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SGPL1

  • Official Full Name

    sphingosine phosphate lyase 1

  • Overview

    Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1 gene.
  • Synonyms

    SGPL1; sphingosine phosphate lyase 1; sphingosine-1-phosphate lyase 1; FLJ13811; hSPL; KIAA1252; S1PL; SGPL 1; SGPL1_HUMAN; SP lyase; SP-lyase 1; Sphingosine 1 phosphate aldolase; Sphingosine 1 phosphate lyase 1; Sphingosine-1-phosphate aldolase; SPL 1; SPL; mSPL; OTTMUSP00000042252; OTTMUSP00000042253; OTTMUSP00000042256; AI428538; D10Xrf456;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SGPL1-501H Recombinant Human SGPL1, His-tagged Sf9 Insect Cell His
Human SGPL1-1297H Recombinant Human SGPL1 protein, His-tagged E.coli His Gln239~Arg493
Human SGPL1-1595HCL Recombinant Human SGPL1 cell lysate N/A
Human SGPL1-1997H-B Recombinant Human SGPL1 Protein Pre-coupled Magnetic Beads HEK293
Human SGPL1-3141H Recombinant Human SGPL1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human SGPL1-2874H Recombinant Human SGPL1 protein, His-tagged E.coli His 69 - 281 aa
Human SGPL1-1997H Recombinant Human SGPL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SGPL1-711HFL Recombinant Full Length Human SGPL1 Protein, C-Flag-tagged Mammalian cells Flag
Mouse Sgpl1-1298M Recombinant Mouse Sgpl1 protein, His & T7-tagged E.coli His/T7 Trp382~Arg568 (Accession # Q8R0X7)
Mouse SGPL1-15042M Recombinant Mouse SGPL1 Protein Mammalian Cell His
Mouse SGPL1-8107M Recombinant Mouse SGPL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Sgpl1-5828M Recombinant Mouse Sgpl1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse SGPL1-8107M-B Recombinant Mouse SGPL1 Protein Pre-coupled Magnetic Beads HEK293
Rat SGPL1-5368R Recombinant Rat SGPL1 Protein Mammalian Cell His
Rat SGPL1-5027R Recombinant Rat SGPL1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat SGPL1-5027R-B Recombinant Rat SGPL1 Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL15852HF Recombinant Full Length Human Sphingosine-1-Phosphate Lyase 1(Sgpl1) Protein, His-Tagged E.coli expression system His Full Length (1-568)
Zebrafish SGPL1-5577Z Recombinant Zebrafish SGPL1 Mammalian Cell His
Chicken SGPL1-1805C Recombinant Chicken SGPL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SGPL1 Related Articles
  • SGPL1 Related Research Area

SGPL1 involved in several pathways and played different roles in them. We selected most pathways SGPL1 participated on our site, such as Sphingolipid metabolism, Metabolic pathways, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Sphingolipid metabolismSERINC1;KDSR;NEU3.1;GLTPD1;GLTP;SMPD2;NEU3.3;ARSE;SGPL1
Metabolic pathwaysACSM1;PCYT1AB;CKB;ALAS1;MTMR1;ST6GALNAC4;PIGQ;DHRS4;UQCRQ
Sphingolipid signaling pathwayMAP2K2;BID;GNA12;CERS5;KRAS;SMPD2;PPP2R5B;RAF1;MAPK12

SGPL1 has several biochemical functions, for example, carboxy-lyase activity, protein binding, pyridoxal phosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPL1 itself. We selected most functions SGPL1 had, and list some proteins which have the same functions with SGPL1. You can find most of the proteins on our site.

Function Related Protein
carboxy-lyase activityBCKDHA;PDXDC1;URAD;AMD2;LOC650128;PDXDC2P;ECHDC1;MVDA;BCKDHB
protein bindingFLT4;TAOK3;ABHD16A;CXCL14;ZNF180;SHD;RFC3;DLL1;KCTD6
pyridoxal phosphate bindingAADAT;CBS;MOCOS;ETNPPL;SPTLC1;CTH;AGXT2L1;MARC1;SHMT1
sphinganine-1-phosphate aldolase activity

SGPL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGPL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGPL1.

TMEM173; compound_31; TMBIM4; midostaurin; ssrna_ug; EGFR; ERBB2; vpu; RPL10; IQCB1; PKN2

Bode, C; Sensken, SC; et al. Erythrocytes Serve as a Reservoir for Cellular and Extracellular Sphingosine 1-Phosphate. JOURNAL OF CELLULAR BIOCHEMISTRY 109:1232-1243(2010).
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