sgpp2
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  • Official Full Name
  • sphingosine-1-phosphate phosphotase 2
  • Synonyms
Cat.#:SGPP2-15044MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SGPP2 Protein
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Involved Pathway

SGPP2 involved in several pathways and played different roles in them. We selected most pathways SGPP2 participated on our site, such as Sphingolipid metabolism, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid metabolism
SPTLC2B; ARSJ; UGCG; SMPD2A; NEU3.1; VAPB; DEGS1; SMPD5; CERS2; CERS1
Sphingolipid signaling pathway
PLD1; AKT1; S1PR4; SGPL1; PIK3R3; PPP2R5C; PPP2CB; PLCB4; TRADD; OPRD1

Protein Function

SGPP2 has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity, IDP phosphatase activity, JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPP2 itself. We selected most functions SGPP2 had, and list some proteins which have the same functions with SGPP2. You can find most of the proteins on our site.
Function
Related Protein
Function 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
Related Protein CTDSPL2A; SACM1L; SACM1LA; TENC1; SGPP2; PXYLP1; CTDSPL2B; SACM1LB; NT5DC3; PTPRQ
Function IDP phosphatase activity
Related Protein SACM1L; PXYLP1; SACM1LA; TENC1; NT5DC3; CTDSPL2B; PTPRQ; SGPP2; CTDSPL2A; SACM1LB
Function JUN kinase phosphatase activity
Related Protein PXYLP1; PTPRQ; SACM1L; SGPP2; SACM1LB; DUSP19; TENC1; CTDSPL2B; SACM1LA; CTDSPL2A
Function MAP kinase tyrosine/serine/threonine phosphatase activity
Related Protein DUSP14; DUSP7; DUSP16; DUSP21; DUSP18; SGPP2; TENC1; SACM1LB; DUSP8A; DUSP1
Function NADP phosphatase activity
Related Protein SGPP2; CTDSPL2A; TENC1; CTDSPL2B; NT5DC3; SACM1LA; SACM1LB; SACM1L; PTPRQ; PXYLP1
Function hydrolase activity
Related Protein DNASE2A; EHD2; GALCA; DUSP8A; THSD4; CAPN2A; TMPRSS4B; MBLAC2; ANG3; FURINA
Function inositol bisphosphate phosphatase activity
Related Protein SGPP2; TENC1; PTPRQ; PXYLP1; NT5DC3; CTDSPL2B; INPP5K; SACM1LB; SACM1L; SACM1LA
Function inositol phosphate phosphatase activity
Related Protein CTDSPL2A; SACM1LA; NT5DC3; SACM1LB; SACM1L; OCRL; PTPRQ; TENC1; PXYLP1; CTDSPL2B
Function inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
Related Protein SGPP2; CTDSPL2B; TENC1; PTPRQ; CTDSPL2A; PXYLP1; SACM1LB; SACM1L; ITPK1; SACM1LA
Function inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
Related Protein SACM1L; CTDSPL2A; PTPRQ; SACM1LB; NT5DC3; SGPP2; PXYLP1; CTDSPL2B; SACM1LA; TENC1
Function inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
Related Protein NT5DC3; SACM1LA; TENC1; PXYLP1; SGPP2; SACM1L; CTDSPL2A; SACM1LB; PTPRQ; CTDSPL2B
Function inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
Related Protein ITPK1; SACM1LB; PXYLP1; TENC1; SGPP2; CTDSPL2B; NT5DC3; CTDSPL2A; PTPRQ; SACM1L
Function inositol-1,3,4-trisphosphate 1-phosphatase activity
Related Protein CTDSPL2A; TENC1; PTPRQ; NT5DC3; PXYLP1; SACM1L; INPP1; SACM1LB; SACM1LA; CTDSPL2B
Function inositol-1,3,4-trisphosphate 4-phosphatase activity
Related Protein CTDSPL2B; PTPRQ; SGPP2; PXYLP1; SACM1L; CTDSPL2A; TENC1; SACM1LB; NT5DC3; SACM1LA
Function inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
Related Protein PXYLP1; SACM1L; NT5DC3; SGPP2; CTDSPL2B; TENC1; SACM1LB; PTPRQ; CTDSPL2A; SACM1LA
Function inositol-3,4-bisphosphate 4-phosphatase activity
Related Protein CTDSPL2A; SACM1L; TENC1; SGPP2; SACM1LA; NT5DC3; PTPRQ; SACM1LB; PXYLP1; CTDSPL2B
Function inositol-4,5-bisphosphate 5-phosphatase activity
Related Protein NT5DC3; PXYLP1; SACM1LB; SACM1LA; TENC1; SACM1L; CTDSPL2A; PTPRQ; CTDSPL2B; SGPP2
Function phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
Related Protein CTDSPL2B; PTPRQ; SACM1LB; TENC1; CTDSPL2A; SGPP2; PXYLP1; NT5DC3; SACM1LA; SACM1L
Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Related Protein MTMR8; SACM1LA; MTMR3; SGPP2; PTPRQ; MTM1; TENC1; SACM1L; SACM1LB; MTMR1A
Function phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
Related Protein NT5DC3; PIKFYVE; PTPRQ; FIG4; SACM1LA; CTDSPL2A; TENC1; SGPP2; SACM1L; CTDSPL2B
Function phosphatidylinositol-4-phosphate phosphatase activity
Related Protein NT5DC3; PTPRQ; SACM1L; SGPP2; SACM1LA; CTDSPL2A; TENC1; PXYLP1; SACM1LB; FIG4
Function phosphohistidine phosphatase activity
Related Protein NT5DC3; SACM1LA; MINPP1; TENC1; CTDSPL2A; PXYLP1; PTPRQ; SGPP2; LHPP; CTDSPL2B
Function protein tyrosine/serine/threonine phosphatase activity
Related Protein DUSP2; EPM2A; DUSP12; DUSP22A; DUSP18; DUPD1; DUSP4; PTP4A2A; PTP4A2B; NT5DC3
Function protein tyrosine/threonine phosphatase activity
Related Protein NT5DC3; SACM1LA; SACM1L; PTPRQ; SACM1LB; DUSP4; PXYLP1; CTDSPL2B; DUSP2; CTDSPL2A
Function sphingosine-1-phosphate phosphatase activity
Related Protein SGPP2; SGPP1; PPAP2B
Function transmembrane receptor protein phosphatase activity
Related Protein TENC1; NT5DC3; SACM1LA; PTPRQ; SACM1LB; SACM1L; CTDSPL2A; CTDSPL2B; SGPP2; PXYLP1

SGPP2 Related Articles

Abuhusain, HJ; Matin, A; et al. A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 288:37355-37364(2013).
Reardon, BJ; Hansen, JG; et al. Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. BMC MEDICAL GENETICS 14:-(2013).