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SGPP2

Official Full Name

sphingosine-1-phosphate phosphotase 2

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SGPP2-15044M	Recombinant Mouse SGPP2 Protein	Mammalian Cell	His	Inquiry
Mouse	SGPP2-8108M	Recombinant Mouse SGPP2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SGPP2-8108M-B	Recombinant Mouse SGPP2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SGPP2 Related Articles

SGPP2 involved in several pathways and played different roles in them. We selected most pathways SGPP2 participated on our site, such as Sphingolipid metabolism, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Sphingolipid metabolism	CERS2;GLA;UGCG;NEU3.4;DEGS2;UGT8;GBA;PPAP2A;ASAH1
Sphingolipid signaling pathway	PPP2R5B;LOC100328615;PLD2;MAPK1;PRKCA;DEGS1;RHOA;MAPK10;GAB2

SGPP2 has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity, IDP phosphatase activity, JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPP2 itself. We selected most functions SGPP2 had, and list some proteins which have the same functions with SGPP2. You can find most of the proteins on our site.

Function	Related Protein
5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	SACM1L;SACM1LB;SGPP2;PXYLP1;NT5DC3;SACM1LA;CTDSPL2B;PTPRQ;TENC1
IDP phosphatase activity	SACM1L;PTPRQ;SGPP2;TENC1;SACM1LA;PXYLP1;CTDSPL2A;NT5DC3;SACM1LB
JUN kinase phosphatase activity	PXYLP1;CTDSPL2B;SACM1LB;SACM1L;SGPP2;NT5DC3;SACM1LA;PTPRQ;DUSP19
MAP kinase tyrosine/serine/threonine phosphatase activity	DUSP1;DUSP7;DUSP4;CTDSPL2A;SACM1LA;SACM1L;DUSP18;TENC1;SGPP2
NADP phosphatase activity	CTDSPL2B;PXYLP1;TENC1;SACM1LA;SGPP2;SACM1L;NT5DC3;CTDSPL2A;SACM1LB
hydrolase activity	CPSF5;KLK1B9;HDAC9B;ATP2B3B;IDI1;PLCD3A;DDX39AA;RHOT1A;KLK13
inositol bisphosphate phosphatase activity	NT5DC3;SACM1LA;SACM1LB;TENC1;SGPP2;CTDSPL2B;PTPRQ;PXYLP1;INPP5K
inositol phosphate phosphatase activity	TENC1;SACM1LB;PXYLP1;PTPRQ;CTDSPL2A;OCRL;NT5DC3;CTDSPL2B;SACM1LA
inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	SGPP2;PTPRQ;SACM1LA;NT5DC3;CTDSPL2A;CTDSPL2B;SACM1LB;TENC1;ITPK1
inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	PXYLP1;TENC1;SACM1L;SACM1LA;CTDSPL2A;SGPP2;NT5DC3;PTPRQ;CTDSPL2B
inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	NT5DC3;PXYLP1;SACM1LB;ITPK1;PTPRQ;CTDSPL2A;SGPP2;SACM1L;SACM1LA
inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	CTDSPL2B;CTDSPL2A;PTPRQ;SACM1LB;SACM1L;NT5DC3;PXYLP1;SGPP2;ITPK1
inositol-1,3,4-trisphosphate 1-phosphatase activity	CTDSPL2A;PXYLP1;PTPRQ;SACM1LA;NT5DC3;SGPP2;CTDSPL2B;SACM1L;INPP1
inositol-1,3,4-trisphosphate 4-phosphatase activity	CTDSPL2A;SACM1LA;SACM1L;PTPRQ;NT5DC3;CTDSPL2B;SACM1LB;TENC1;PXYLP1
inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	NT5DC3;PXYLP1;PTPRQ;CTDSPL2A;SACM1LB;TENC1;SGPP2;SACM1L;SACM1LA
inositol-3,4-bisphosphate 4-phosphatase activity	PXYLP1;SACM1L;SGPP2;CTDSPL2A;NT5DC3;TENC1;SACM1LB;CTDSPL2B;PTPRQ
inositol-4,5-bisphosphate 5-phosphatase activity	NT5DC3;TENC1;PXYLP1;SACM1LB;SACM1L;CTDSPL2B;SACM1LA;SGPP2;CTDSPL2A
phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	CTDSPL2A;SACM1L;PTPRQ;TENC1;SACM1LB;CTDSPL2B;SGPP2;NT5DC3;SACM1LA
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	PXYLP1;MTMR8;SACM1LB;SACM1L;SACM1LA;PTPRQ;SGPP2;MTMR2;MTMR1A
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	SGPP2;PXYLP1;SACM1L;FIG4;SACM1LA;TENC1;CTDSPL2B;SACM1LB;NT5DC3
phosphatidylinositol-4-phosphate phosphatase activity	NT5DC3;PTPRQ;PXYLP1;CTDSPL2B;SGPP2;SACM1LA;TENC1;FIG4;CTDSPL2A
phosphohistidine phosphatase activity	PTPRQ;SACM1LA;NT5DC3;CTDSPL2A;TENC1;LHPP;SACM1L;SGPP2;PXYLP1
protein tyrosine/serine/threonine phosphatase activity	DUSP16;PTP4A2B;SACM1LB;PTP4A2A;CDKN3;EYA3;SGPP2;CTDSPL2A;DUSP13A
protein tyrosine/threonine phosphatase activity	NT5DC3;DUSP4;DUSP19;CTDSPL2B;PXYLP1;TENC1;SACM1L;PTPRQ;SACM1LA
sphingosine-1-phosphate phosphatase activity	SGPP2;SGPP1;PPAP2B
transmembrane receptor protein phosphatase activity	SACM1L;CTDSPL2A;SACM1LA;TENC1;SACM1LB;NT5DC3;SGPP2;PXYLP1;CTDSPL2B

SGPP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SGPP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SGPP2.

Abuhusain, HJ; Matin, A; et al. A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 288:37355-37364(2013).

Reardon, BJ; Hansen, JG; et al. Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. BMC MEDICAL GENETICS 14:-(2013).