sgpp2
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  • Official Full Name
  • sphingosine-1-phosphate phosphotase 2
  • Synonyms
Cat.#:SGPP2-15044MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SGPP2 Protein
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Involved Pathway

SGPP2 involved in several pathways and played different roles in them. We selected most pathways SGPP2 participated on our site, such as Sphingolipid metabolism, Sphingolipid signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SGPP2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Sphingolipid metabolism
SMPD4; SMPD1; PPM1LA; NEU2; PPM1L; SPTLC2B; B4GALT6; LASS2; GAL3ST1; SPTLC1
Sphingolipid signaling pathway
SGPP1; PPP2R3C; ROCK1; GNA12; RAC3; PIK3R1; LASS5; PDPK1; MAP2K1; HRAS

Protein Function

SGPP2 has several biochemical functions, for example, 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity, IDP phosphatase activity, JUN kinase phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SGPP2 itself. We selected most functions SGPP2 had, and list some proteins which have the same functions with SGPP2. You can find most of the proteins on our site.
Function
Related Protein
Function 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity
Related Protein CTDSPL2A; NT5DC3; SACM1L; CTDSPL2B; SGPP2; SACM1LB; PTPRQ; SACM1LA; TENC1; PXYLP1
Function IDP phosphatase activity
Related Protein SACM1L; CTDSPL2B; PTPRQ; PXYLP1; SACM1LA; NT5DC3; TENC1; SACM1LB; CTDSPL2A; SGPP2
Function JUN kinase phosphatase activity
Related Protein SACM1LA; TENC1; NT5DC3; PTPRQ; DUSP19; CTDSPL2A; CTDSPL2B; SACM1L; PXYLP1; SGPP2
Function MAP kinase tyrosine/serine/threonine phosphatase activity
Related Protein DUSP21; PXYLP1; PTPRQ; DUSP5; DUSP2; DUSP7; NT5DC3; CTDSPL2A; CTDSPL2B; DUSP6
Function NADP phosphatase activity
Related Protein TENC1; PTPRQ; SGPP2; SACM1LB; CTDSPL2A; CTDSPL2B; SACM1LA; SACM1L; NT5DC3; PXYLP1
Function hydrolase activity
Related Protein AADACL4; ABHD17B; KLK13; GZMF; ST14A; PTPRQ; DHX57; PSMB9A; PNPLA1; AGBL4
Function inositol bisphosphate phosphatase activity
Related Protein NT5DC3; SACM1LB; SACM1L; TENC1; CTDSPL2B; SACM1LA; PXYLP1; SGPP2; CTDSPL2A; PTPRQ
Function inositol phosphate phosphatase activity
Related Protein CTDSPL2A; SACM1LA; PXYLP1; SACM1LB; OCRL; TENC1; NT5DC3; CTDSPL2B; PTPRQ; SACM1L
Function inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity
Related Protein SACM1LA; TENC1; SACM1LB; SACM1L; ITPK1; SGPP2; PXYLP1; CTDSPL2B; NT5DC3; PTPRQ
Function inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity
Related Protein PXYLP1; NT5DC3; PTPRQ; CTDSPL2B; CTDSPL2A; TENC1; SACM1L; SACM1LB; SACM1LA; SGPP2
Function inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity
Related Protein SGPP2; SACM1LB; SACM1L; PTPRQ; CTDSPL2A; NT5DC3; PXYLP1; SACM1LA; ITPK1; CTDSPL2B
Function inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity
Related Protein NT5DC3; TENC1; CTDSPL2A; SACM1LB; CTDSPL2B; PXYLP1; SGPP2; PTPRQ; SACM1LA; ITPK1
Function inositol-1,3,4-trisphosphate 1-phosphatase activity
Related Protein PXYLP1; INPP1; TENC1; SACM1LB; PTPRQ; CTDSPL2A; SACM1L; NT5DC3; CTDSPL2B; SGPP2
Function inositol-1,3,4-trisphosphate 4-phosphatase activity
Related Protein TENC1; PTPRQ; SACM1LA; SGPP2; PXYLP1; SACM1L; SACM1LB; CTDSPL2B; NT5DC3; CTDSPL2A
Function inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity
Related Protein NT5DC3; PXYLP1; CTDSPL2B; SACM1L; SACM1LB; CTDSPL2A; SGPP2; TENC1; PTPRQ; SACM1LA
Function inositol-3,4-bisphosphate 4-phosphatase activity
Related Protein TENC1; SGPP2; PXYLP1; SACM1LB; SACM1LA; PTPRQ; SACM1L; NT5DC3; CTDSPL2B; CTDSPL2A
Function inositol-4,5-bisphosphate 5-phosphatase activity
Related Protein CTDSPL2A; PTPRQ; PXYLP1; TENC1; SACM1LB; SGPP2; SACM1LA; NT5DC3; CTDSPL2B; SACM1L
Function phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity
Related Protein PTPRQ; TENC1; CTDSPL2A; SACM1LA; NT5DC3; SACM1L; SGPP2; PXYLP1; SACM1LB; CTDSPL2B
Function phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
Related Protein MTMR1A; NT5DC3; CTDSPL2B; SACM1LB; TENC1; SGPP2; CTDSPL2A; PTPRQ; SACM1LA; MTMR1
Function phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
Related Protein SACM1L; CTDSPL2A; PIKFYVE; SACM1LA; PXYLP1; FIG4; CTDSPL2B; TENC1; PTPRQ; SGPP2
Function phosphatidylinositol-4-phosphate phosphatase activity
Related Protein CTDSPL2A; CTDSPL2B; PTPRQ; TENC1; SACM1LB; NT5DC3; SACM1L; FIG4; PXYLP1; SACM1LA
Function phosphohistidine phosphatase activity
Related Protein SGPP2; PXYLP1; PHPT1; MINPP1; CTDSPL2B; PTPRQ; TENC1; SACM1L; NT5DC3; SACM1LB
Function protein tyrosine/serine/threonine phosphatase activity
Related Protein DUSP2; CDC14AA; DUSP22B; DUSP13; DUSP23; PTENB; SACM1LA; CDC14A; DUSP4; DUSP23B
Function protein tyrosine/threonine phosphatase activity
Related Protein DUSP1; CTDSPL2A; SACM1LB; DUSP2; DUSP4; PTPRQ; TENC1; SACM1L; SGPP2; PXYLP1
Function sphingosine-1-phosphate phosphatase activity
Related Protein SGPP2; PPAP2B; SGPP1
Function transmembrane receptor protein phosphatase activity
Related Protein TENC1; SGPP2; PTPRQ; PXYLP1; SACM1LA; CTDSPL2B; NT5DC3; SACM1L; CTDSPL2A; SACM1LB

SGPP2 Related Articles

Abuhusain, HJ; Matin, A; et al. A Metabolic Shift Favoring Sphingosine 1-Phosphate at the Expense of Ceramide Controls Glioblastoma Angiogenesis. JOURNAL OF BIOLOGICAL CHEMISTRY 288:37355-37364(2013).
Reardon, BJ; Hansen, JG; et al. Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. BMC MEDICAL GENETICS 14:-(2013).