SHARPIN
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Official Full Name
SHANK-associated RH domain interactor
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Synonyms
SHARPIN; SHANK-associated RH domain interactor; DKFZP434N1923; SIPL1; hSIPL1; Shank associated RH domain interacting protein; SHANK associated RH domain interactor; Shank interacting protein like 1; Shank-associated RH domain-interacting protein; Shank-interacting protein-like 1; SHRPN_HUMAN;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- MYC
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | SHARPIN-2653H | Recombinant Human SHARPIN, GST-tagged | E.coli | GST | 1-326aa | |
Human | SHARPIN-1601HCL | Recombinant Human SHARPIN cell lysate | N/A | |||
Human | SHARPIN-3420H | Recombinant Human SHARPIN protein, His-tagged | E.coli | His | 1-326 aa | |
Human | SHARPIN-1033H | Recombinant Human SHARPIN Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Mouse | SHARPIN-15087M | Recombinant Mouse SHARPIN Protein | Mammalian Cell | His | ||
Mouse | SHARPIN-8138M-B | Recombinant Mouse SHARPIN Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Sharpin-288M | Recombinant Mouse Sharpin Protein, MYC/DDK-tagged | HEK293T | MYC/DDK | ||
Mouse | SHARPIN-8138M | Recombinant Mouse SHARPIN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SHARPIN-5388R | Recombinant Rat SHARPIN Protein | Mammalian Cell | His | ||
Rat | SHARPIN-5047R | Recombinant Rat SHARPIN Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | SHARPIN-5047R-B | Recombinant Rat SHARPIN Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
- SHARPIN Related Articles
- SHARPIN Related Research Area
SHARPIN involved in several pathways and played different roles in them. We selected most pathways SHARPIN participated on our site, such as Death Receptor Signalling, Regulation of TNFR1 signaling, Signal Transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHARPIN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Death Receptor Signalling | TAB1;TAX1BP1;OTULIN;TAX1BP1B;OTUD7B;SHRPRBCK1R;CLIP3;USP2;RBCK1 |
Regulation of TNFR1 signaling | OTUD7B;SHRPRBCK1R;FAM105B;TAX1BP1;TAX1BP1B;RNF31;RBCK1;OTULIN;USP4 |
Signal Transduction | NEDD8L;MKS1;LPAR5A;NPSR1;METAP2B;RHOUA;CLIP3;FSTL3;ARHGAP4A |
TNF signaling | CLIP3;OTUD7B;TAX1BP1;OTULIN;SHRPRBCK1R;FAM105B;USP4;SHARPIN;TAX1BP1B |
TNFR1-induced NFkappaB signaling pathway | SHARPIN;SHRPRBCK1R;RNF31;OTUD7B;USP4;USP2 |
SHARPIN has several biochemical functions, for example, identical protein binding, polyubiquitin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHARPIN itself. We selected most functions SHARPIN had, and list some proteins which have the same functions with SHARPIN. You can find most of the proteins on our site.
Function | Related Protein |
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identical protein binding | SUN2;CSK;PCM1;CLDND;RIPK3;PCNA;TTC32;TOPBP1;GRIN3A |
polyubiquitin binding | EPS15;PSMD4A;FAM175A;FAM175B;BRE;RAD23A;SHARPIN;UBQLN4;RAD18 |
protein binding | APBB1;NUDC;PRF1;GJA1;MC2R;EPN3;MIF;TMEM149;LRRIQ3 |
protein complex binding | EP300;TUB;LEPRE1;EPHB1;PTPRF;PPFIA2;CDK5RAP2;NCKAP1L;NRAS |
zinc ion binding | PRKCBB;ZMYND11;MDM2;LIMCH1A;TEX13A;SHANK3;ZBBX;DTNA;USP13 |
SHARPIN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHARPIN here. Most of them are supplied by our site. Hope this information will be useful for your research of SHARPIN.
ITGA2; ITGA5; RNF31; TNF; IKBKG; TNFAIP3; IL1A
- Q&As
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