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SHROOM2

Official Full Name

shroom family member 2
Overview

The protein encoded by this gene shares significant similarities with the apical protein from Xenopus laevis which is implicated in amiloride-sensitive sodium channel activity. This gene is a strong candidate gene for ocular albinism type 1 syndrome.
Synonyms

SHROOM2; shroom family member 2; apical protein, Xenopus laevis like , apical protein like (Xenopus laevis) , APXL; protein Shroom2; 4832440C16; Ab2-404; Apical like protein; Apical like protein APXL protein; apical protein of Xenopus-like; Apical protein Xenopus laevis like; apical protein, Xenopus laevis-like; apical protein-like; apical protein-like (Xenopus laevis); Apical-like protein; APX homolog of Xenopus; C630003H05Rik; DKFZp781J074; FLJ39277; HSAPXL; Liver regeneration-related protein LRRG167; OTTHUMP00000022887; Protein Apxl; Shrm2; SHRM2_HUMAN; SHROOM 2; APXL;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SHROOM2-15116M	Recombinant Mouse SHROOM2 Protein	Mammalian Cell	His	Inquiry
Mouse	SHROOM2-8164M	Recombinant Mouse SHROOM2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SHROOM2-8164M-B	Recombinant Mouse SHROOM2 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

SHROOM2 involved in several pathways and played different roles in them. We selected most pathways SHROOM2 participated on our site, such as Tight junction, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHROOM2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Tight junction	CLDN16;CLDN17;CLDN9;PPP2R2CA;MYH1B;VAPA;CLDN11;ASH1L;AKT3A

SHROOM2 has several biochemical functions, for example, actin binding, actin filament binding, beta-catenin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHROOM2 itself. We selected most functions SHROOM2 had, and list some proteins which have the same functions with SHROOM2. You can find most of the proteins on our site.

Function	Related Protein
actin binding	PXK;MYH9;SPIRE1;HPCA;ABRA;FER;EPS8;ENC1;PALLD
actin filament binding	TLN1;ANTXR1;LCP1;TAGLN3B;TLN2A;WIPF3;TRIOBPB;AIF1L;MYO1A
beta-catenin binding	AXIN1;CDH24;DACT1;SLC9A3R2;CD2AP;GRIP1;CTNNA3;CARM1;PTBP3
protein binding	FAM83A;NXF3;DEF6;PRICKLE1A;SOX1;MYO7B;LARP1;HSPB9;UBA5
protein domain specific binding	CBX3;HIST2H4;TJP1;VRK2;MTOR;HIST1H4I;YWHAE2;MLF1;NLRP1

SHROOM2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHROOM2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHROOM2.