Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

Siah1a

Official Full Name

seven in absentia 1A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Mouse	SIAH1A-15120M	Recombinant Mouse SIAH1A Protein	Mammalian Cell	His	Inquiry
Mouse	SIAH1A-8168M	Recombinant Mouse SIAH1A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	SIAH1A-8168M-B	Recombinant Mouse SIAH1A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein

Siah1a involved in several pathways and played different roles in them. We selected most pathways Siah1a participated on our site, such as p signaling pathway, Ubiquitin mediated proteolysis, Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Siah1a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
p signaling pathway	SESN2;STEAP3;MDM2;CCNB3;CCNE1;PTENA;RRM2B;TP53;CD82A
Ubiquitin mediated proteolysis	UBE2E3;UBE3C;TCEB1B;UBE2D1;NEDD4L;ANAPC4;MDM2;PIAS2;CDC20
Wnt signaling pathway	PRICKLE2B;MAPK8A;CER1;FZD7;PRKACAB;DKK2;NFATC1;TCF7L2;PRKCBA

Siah1a has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Siah1a itself. We selected most functions Siah1a had, and list some proteins which have the same functions with Siah1a. You can find most of the proteins on our site.

Function	Related Protein
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	UBE2IA;RFWD2;G2E3;MARCH6;NEURL3;MYLIPB;RNF144AB;RNF187;TRIM50
coenzyme F420-0 gamma-glutamyl ligase activity	DTX1;G2E3;MYLIPA;MUL1A;MARCH4;ZNRF2B;MGRN1A;TRIM50;HERC2
coenzyme F420-2 alpha-glutamyl ligase activity	MGRN1A;UBR1;RNF187;ZNRF2B;SHRPRBCK1R;RNF144AB;RNF180;UBE2IA;ITCHA
identical protein binding	MAPK1IP1;ADIPOQ;EPHA4;BRAP;NME1;PYCARD;G6PD;MSANTD3;SERPINB1A
ligase activity	UBE4B;RNF111;TRIM39;UBE3B;NAPRT1;SH3RF1;FPGS;TTLL9;BIRC3
metal ion binding	CYP2P9;ZDHHC3B;ADSSL;ZNF529;ZNF202;ZNF521;ZFP2;CYP4A14;NR4A2B
protein C-terminus binding	PDZD3;ERBB2;TOP2A;ERCC6;SHANK3;MIF4GD;HAND2;IFT52;PROP1
protein binding	TBRG4;FKBP3;NOG;RABAC1;ERG;DNMT3A;ANGPTL4;GPR3;C19orf25
protein homodimerization activity	COMMD1;GHR;CLIC6;MBL1;PRDX4;MCL1B;CER1;USF2;NADKD1
protein-glutamic acid ligase activity	UBE2IB;RNF169;RFWD2;MARCH9;TRIM41;SIAH2L;MUL1A;MYLIPA;RNF187
protein-glycine ligase activity	UBR1;MGRN1A;ARIH1L;MUL1A;MYLIPB;RNF169;RNF149;G2E3;MARCH9
protein-glycine ligase activity, elongating	RNF144AA;NEURL1B;RAG1;RNF180;SIAH2L;G2E3;RNF149;ZNRF3;UBE2IA
protein-glycine ligase activity, initiating	RNF169;G2E3;MGRN1A;MUL1A;HERC2;MARCH5L;RNF144AB;SIAH2L;DTX1
ribosomal S6-glutamic acid ligase activity	MUL1A;MARCH9;NEURL3;RNF149;TRIM71;RNF187;NEURL1B;RNF169;ITCHA
tubulin-glutamic acid ligase activity	HECW2;UBR1;RC3H2;RNF180;MARCH9;G2E3;HERC2;ITCHA;RNF169
tubulin-glycine ligase activity	ZNRF3;TRIM71;MARCH9;RNF169;MARCH4;MUL1A;TRIM50;NEURL1B;MYLIPB
ubiquitin protein ligase activity	TRIM63;UBE2KA;MGRN1;HECTD1;MED20;PDZRN4;TRIM3;ARIH1;TRIP12
ubiquitin-protein transferase activity	RNF144AB;TRIM36;UBE2E2;TRIM13;FBXL21;RNF6;MUL1B;TRIM21;TRAF5
zinc ion binding	ADAM10A;ZFAND6;MT2;MARCH2;PAPPA2;BTR06;FANCL;PARP1;BMI1A

Siah1a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Siah1a here. Most of them are supplied by our site. Hope this information will be useful for your research of Siah1a.

Dab1; Sh3rf1; AGAP2