SIK1
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Official Full Name
salt-inducible kinase 1
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Overview
Serine/threonine-protein kinase SIK1 is an enzyme that in humans is encoded by the SIK1 gene. -
Synonyms
SIK1; salt-inducible kinase 1; SNF1 like kinase , SNF1LK; serine/threonine-protein kinase SIK1; msk; myocardial SNF1 like kinase; SIK-1; SNF1-like kinase; myocardial SNF1-like kinase; salt-inducible protein kinase 1; serine/threonine protein kinase; serin;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Assay Kits
- Chicken
- Human
- Human
- Mouse
- Rat
- E.coli
- HEK293
- Insect Cell
- Mammalian Cell
- Sf21
- Sf9 Insect Cell
- GST
- His
- HIS
- His (Fc)
- Avi
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
- SIK1 Related Signal Pathway
SIK1 involved in several pathways and played different roles in them. We selected most pathways SIK1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SIK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
SIK1 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SIK1 itself. We selected most functions SIK1 had, and list some proteins which have the same functions with SIK1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|
SIK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIK1.
YWHAZ; CRTC2; SUPT5H; RPL3; NMNAT1; CD247; YWHAE
- Q&As
- Reviews
Q&As (5)
Ask a questionDysregulation of SIK1 has been implicated in cancer. It can influence cell proliferation and survival by affecting the activity of transcription factors involved in cell cycle control and apoptosis.
SIK1 plays a role in adipose tissue metabolism by modulating the activity of transcription factors involved in lipogenesis and lipolysis. Dysregulation may contribute to metabolic disorders like obesity and insulin resistance.
SIK1, or Salt-Inducible Kinase 1, is involved in the regulation of cellular responses to various stimuli, including stress, metabolism, and inflammation.
SIK1 regulates energy homeostasis by phosphorylating and modulating the activity of key metabolic regulators, such as cAMP response element-binding protein (CREB) and class IIa histone deacetylases.
SIK1 is activated in response to environmental stressors, such as osmotic stress. It regulates stress signaling pathways through the phosphorylation of downstream effectors, modulating cellular stress responses.
Customer Reviews (3)
Write a reviewOur lab swears by this product! It's a versatile and reliable tool for our experiments.
The quality control is evident in the data precision we achieve.
As a researcher, I can't live without this product. Makes my experiments more accurate and efficient.
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