sik3
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  • Official Full Name
  • SIK family kinase 3
  • Background
  • KIAA0999 protein is a protein that in humans is encoded by the SIK3 gene.
  • Synonyms
  • SIK3; SIK family kinase 3; serine/threonine-protein kinase SIK3; FLJ12240; KIAA0999; L19; QSK; Salt inducible kinase 3; serine/threonine-protein kinase QSK; SIK 3; salt-inducible kinase 3; SIK-3
Cat.#:SIK3-1482HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human SIK3 (Active), GST-tagged
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Involved Pathway

SIK3 involved in several pathways and played different roles in them. We selected most pathways SIK3 participated on our site, such as LKB1 signaling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with SIK3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
LKB1 signaling events
MARK4; CDC37; MAP2; CTSD; SIK3; MARK2; STK11IP

Protein Function

SIK3 has several biochemical functions, for example, ATP binding, magnesium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SIK3 itself. We selected most functions SIK3 had, and list some proteins which have the same functions with SIK3. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein MET; MUSK; GSK3AB; GKUP; ATP13A3; PL10; ATP2A2A; PDK4; ATP8B1; VMHCL
Function magnesium ion binding
Related Protein CLYBL; TSSK6; TSSK1; STK36; ATP4A; ENO2; CDC42BPA; SIK2; TDP2B; PKLR
Function protein binding
Related Protein GKAP1; MCEE; PTPRN; LGR4; SPINK2; PRKX; PHF19; PDIA6; SEMA7A; ATRX
Function protein serine/threonine kinase activity
Related Protein PAK2; GM7168; PRKY; TESK2; NEK11; BCR; OBSCN; PAK1; TAOK2; PKN1B

Interacting Protein

SIK3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SIK3 here. Most of them are supplied by our site. Hope this information will be useful for your research of SIK3.
YWHAZ; CRTC2; PRKACA; TRIP6; czc8004; bosutinib; imatinib; midostaurin; YWHAE